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Mauro Bonanini
Department of Biomedical, Biotechnological and Translational Sciences–Center of Oral Pathology and Laser Surgery, University of Parma, Via Gramsci, Parma 14-43100
Dentistry

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An Auto-fluorescence Guided Surgical Approach Performed with Er:YAG Laser and Nd:YAG Low Level Laser Therapy for Medication-related Osteonecrosis of the Jaw Giovannacci,, Ilaria; Meleti, Marco; Bonanini, Mauro; Vescovi, Paolo
Journal of Dentistry Indonesia Vol. 22, No. 2
Publisher : UI Scholars Hub

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Medication-Related Osteonecrosis of the Jaw (MRONJ) therapy remains an unresolved problem. The proposed conservative and surgical treatment regimens are associated to contradictory success rates. Surgical approach with Er:YAG laser is associated to significant better results compared to medical treatment and traditional surgical approaches. Objective: To describe a new surgical approach that couples the advantages of the Er:YAG laser and the usefulness of the AF in highlighting surgical margins. One of the difficulties encountered during surgical removal of a MRONJ is the precise individuation of necrotic bone margins. Case Report: A case of Stage III mandibular osteonecrosis treated with a new surgical approach is presented. The aim is to describe an auto-fluorescence (AF) guided surgical approach performed with Er:YAG laser and Nd:YAG Low Level Laser Therapy (LLLT). After one month of follow-up, the complete mucosal healing was evident and symptoms was unobserved. Such a technique allowed a highly accurate and minimally invasive approach through the selective ablation of the non-/hypofluorescent areas. Conclusion: Taking into account the advantages of laser therapy and the possible effectiveness of the AF in highlighting surgical margins, this approach would probably achieve excellent outcomes.
Pain and Health-Related Quality of Life After Oral Soft Tissue Surgical Intervention: The Advantages of the Nd:YAG Laser Giovannacci, Ilaria; Vescovi, Paolo; Mergoni, Giovanni; Fornaini, Carlo; Bonanini, Mauro; Meleti, Marco
Journal of Dentistry Indonesia Vol. 21, No. 2
Publisher : UI Scholars Hub

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The new technology such as the neodymium-doped yttrium aluminum garnet (Nd:YAG) laser has been used for oral soft tissue surgery. Previous study shown that laser surgery resulted in lower morbidity and complication rates. Objective: This study aims to evaluate the differences in the post-operative course associated to the use of Nd:YAG laser and to cold blade after oral soft tissue surgery. Methods: One-hundred and eighteen comparable surgical interventions were evaluated. Group 1 (G1) included 77 interventions performed with Nd:YAG laser; group 2 (G2) 41 with cold blade. Acute post-operative pain was evaluated with visual analogue scale (VAS), numeric rating scale (NRS) and verbal rating scale-6 (VRS-6) on the same day of surgery, and at 1, 3 and 7 days after surgery.The HRQoL was evaluated on day 7 using a 0-45 score range questionnaire. Data were analyzed using the software STATA 12 (StataCorp LP, College Station, Texas, USA). Results: No statistically significant differences could be highlighted in VAS and NRS scores. The VRS-6 scores resulted statistically significant at days 1 and 3. At day 1, 47.14% of patients in G1 and 13.16% in G2 had no pain; at day 3, 62.86% in G1 and 21.05% in G2 had no pain. The HRQoL in G1 was statistically higher than G2. Conclusion: The better HRQoL and the lower post-operative pain observed in laser-treated patients may be associated to the possible bio-modulating effect of the laser.
Co-Authors Carlo Fornaini Giovannacci,, Ilaria Giovanni Mergoni Ilaria Giovannacci Marco Meleti Paolo Vescovi