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All Journal Indian Journal of Forensic Medicine & Toxicology
Bushra Abbas alzubaidi
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Public Health

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Effect of Oxymetholone on The Sperm Quality and Sex Hormone Profile in Male Rats Zahraa Lateef Abd; Bushra Abbas alzubaidi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14926

Abstract

The objective of present study was to evaluated the effect of Oxymetholone drug on sperm parametersand sex hormone in adult male rats. Twenty male rats sexually mature were randomly divided into twogroups; Each group has 10 rats. The treated group administered orally with Oxymethololne drug 5 mg/gbody weight/ day of for 60 days while the control group administered orally normal saline per day. SPSSanalysis of data generated with P< 0.05 considered statistically significant. The results showed a significantdecrease (p <0.05) in the mean sperm count, the motility and viability in treated group compared to control.Also, LH (luteinizing hormone) FSH (follicle stimulating hormone) and T (testosterone) of the treated groupwere significantly lowered compared to the control. The administration of Oxymethylene induces low spermquality with reduction in sex hormone.
Co-Authors Zahraa Lateef Abd