Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal Indian Journal of Forensic Medicine & Toxicology Journal of Medical Genetics and Clinical Biology (JMGCB)
Muna Salah Rasheed
Unknown Affiliation
Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Reducing of Hydrogen Peroxide Effects by Pomegranate Peel Extract in Vivo, in Female Wistar Rats Dhuha Salah Noori; Agharid. A.Al-Rasheed; Muna Salah Rasheed; Bashiru Garba
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.15028

Abstract

In this study, the effect of pomegranate peel aqueous extract (PPEA) in reducing toxicities associated withhydrogen peroxide consumption was investigated using rats. This was achieved by assessing the serumbiochemical parameters as well as histopathological analysis of the liver and stomach sections. Forty,6-week-old female Wistar albino rats weighing 11.6± 4.4 g were divided equally into six groups. The ratswere administered the pomegranate extract and challenged with H2O2 via the oral route for 28 days. Toachieve this, positive control rats ingested H2O2 at 5 mg/ 100g body weight (b.w), while the negative controlgroups were given saline solution. Rats in the other three experimental groups were given H2O2 and treatedwith PPEA at 20, 40 mg and Vitamin at 25mg per 100g body weight respectively.H2O2 at 5 mg/100 g b.winduced injury to the liver and stomach tissues, while increasing levels of malondialdehyde (MDA), theAspartate Transaminase (AST) besides Alanine Transaminase (ALT) and, reduced of Glutathione GSH)were observed in comparison with the control groups. Treatment with PPEA demonstrated protective effectsby reducing the MDA, ALT and AST values and increase of GSH level as well as, improving the liver andstomach tissues to recover. Our results indicate that the administration of treatments against H2O2 usingPPEA decrease the harmful effect orally administered H2O2 at 5 mg/100g b.w.
EVALUATE THE EFFECT OF ORLISTAT, LIRAGLUTIDE, AND THE HERBAL SUPPLEMENT ON THE MOTHERS OF EXPERIMENTALLY FATTENED WHITE RATS Zainab Hasan Majeed; Ektifa Abdul Hamid Muhammad; Muna Salah Rasheed
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 6 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i6.583

Abstract

The current study aimed to evaluate the effect of orlistat, liraglutide, and the herbal supplement on the mothers of experimentally fattened white rats. The female rats were divided into two main groups, the first fed a standard ration, in which two groups were the first pregnant and the second non-pregnant, while the second main group was fed a special diet containing 35%. Fat for the purpose of fattening as a first stage and for a period of 6 weeks, then the second stage began, which is the pregnancy and treatment stage and included eight secondary groups. The first group was not treated with any drug, the second group was orlistat at a therapeutic dose, the third group was liraglutide at a therapeutic dose, the fourth group was an herbal supplement, and the fifth group was a supplement with a therapeutic dose. Of Orlistat, the sixth group is supplemented with a therapeutic dose of liraglutide, the seventh group is a high dose of orlistat, and the eighth group is a high dose of liraglutide. The current study showed that the obesity leads to changes in lipid profiles compared to control groups, as the effect of fattening is represented by an increase in the concentration of total cholesterol, triglycerides, low-density lipoproteins, very low-density lipoproteins, and a decrease in high-density lipoproteins, histological examinations. Pathological changes appeared in each of the liver tissues, represented by a large proliferation of fat droplets, steatosis, Müller bodies, collapse of the central vein wall, and lymphocytic infiltration. The two best groups were when the herbal supplement was used with both drugs, and the herbal supplement had a synergistic role. With the two drugs, it reduces the accumulation of fat in the cells.
Co-Authors Agharid. A.Al-Rasheed Bashiru Garba Dhuha Salah Noori Ektifa Abdul Hamid Muhammad Zainab Hasan Majeed