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All Journal Jurnal Anestesiologi Indonesia The Indonesian Journal of Occupational Safety and Health The Indonesian Biomedical Journal
Budiono Budiono
Departemen Ilmu Kesehatan Masyarakat-Kedokteran Pencegahan, Fakultas Kedokteran, Universitas Airlangga, Surabaya
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Public Health

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Analisis Faktor Risiko terhadap Lama Perawatan Pasien Sepsis yang Meninggal di Ruang Perawatan Intensif RSUD Dr. Soetomo Surabaya Fajra Arif Hatman; Bambang Pujo Semedi; Budiono Budiono
JAI (Jurnal Anestesiologi Indonesia) Vol 13, No 2 (2021): Jurnal Anestesiologi Indonesia
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jai.v13i2.32441

Abstract

Latar Belakang: Sepsis disebabkan oleh ketidakseimbangan respons tubuh terhadap infeksi dan dapat mengakibatkan komplikasi yang berbahaya. Komplikasi yang ditimbulkan bervariasi, salah satu yang paling sering adalah disfungsi organ yang dapat dinilai melalui skor sequential organ failure assessment (SOFA). Sepsis masih menjadi masalah kesehatan karena sulitnya pengobatan dan lama perawatan yang lama sehingga menyebabkan mortalitas yang tinggi. Sepsis memiliki berbagai penyebab di antaranya pneumonia yang diketahui menjadi salah satu penyebab infeksi terbanyak pada sepsis. Selain itu, mikroorganisme juga menjadi salah satu penyebab infeksi terbanyak di ruang perawatan intensif. Pemeriksaan laboratorium memiliki hasil yang buruk pada banyak pasien sepsis seperti anemia dan leukositosis.Tujuan: Tujuan penelitian ini untuk menganalisis faktor risiko meliputi riwayat penyakit, riwayat konsumsi obat, diagnosis masuk, dan jumlah alat medis invasif terhadap lama perawatan dan mengetahui karakteristik pasien sepsis yang meninggal.Metode: Penelitian ini merupakan penelitian observasional analitik dengan menggunakan data rekam medis 42 pasien sepsis yang meninggal di ruang perawatan intensif RSUD Dr. Soetomo Surabaya. Data dideskripsikan dan dianalisis menggunakan software SPSS 26.Hasil: Terdapat 18 (42,86%) laki-laki dan 24 (57,14%) perempuan dengan rata-rata usia 55,98 + 15,411. Didapatkan median skor SOFA 7,5 (3–15) dengan sistem respirasi menjadi tempat infeksi terbanyak (50%). Pemeriksaan laboratorium menunjukkan banyak pasien sepsis mengalami anemia (66,67%) dan leukositosis (59,52%). Acinetobacter baumannii (26,08%) sebagai mikroorganisme yang paling banyak ditemukan. Hasil penelitian ditemukan hanya diagnosis masuk yang memiliki hubungan dengan lama perawatan (P = 0,05). Di sisi lain tidak ditemukan faktor risiko yang berpengaruh terhadap lama perawatan >5 hari (P > 0,05).Kesimpulan: Diagnosis masuk memperpanjang lama perawatan.  Tidak ada faktor risiko yang berpengaruh terhadap durasi perawatan >5 hari. Karakteristik pasien secara umum memiliki kondisi medis yang buruk. 
Literature Review: Occupational Safety and Health Risk Factors of Healthcare Workers during COVID-19 Pandemic Prima Ardiansah Surya; Marsheila Harvy Mustikaningtyas; Sacharissa Zerlina Tsarwah Thirafi; Afika Danedea Pramitha; Laksita Taffara Mahdy; Gery Morales Munthe; Adivia Cheries Dwiantoro; Budiono Budiono
The Indonesian Journal of Occupational Safety and Health Vol. 10 No. 1 (2021): The Indonesian Journal of Occupational Safety and Health
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (789.391 KB) | DOI: 10.20473/ijosh.v10i1.2021.144-152

Abstract

Introduction: The pandemic of COVID-19 has major effects, particularly on hospitals and health workers. At the beginning of March, more than 3,300 health workers have beencontracted with COVID-19 as reported by China's National Health Commission. Twenty percent of healthcare workers in Italy have also also infected and some died. To minimize the risk of transmission to health workers, knowledge of the risk factors that influence the transmission is needed. Thus, this study aims to determine risk factors related to occupational safety and health for healthcare workers during the COVID-19 pandemic. Methods: The literature was searched on Pubmed, Google Scholar, WHO, and the Ministry of Health instruments were implemented. 8 relevant studies were reviewed. Results: According to the analysis results of several studies, the use of PPE that is less consistent and not suitable with the risk of exposure will increase the risk of infection. The risk of infection is also increased by poor hand hygiene. According to the Kaplan-Meier curve, the working duration of ≥ 15 hours will increase the risk of infection. The risk of infection also exists for health workers who carry out risky procedures that generate airborne particles such as resuscitation, as well as environmental factors such as negative pressure rooms and traffic control bundling. Conclusion: Risk factors related to occupational health and safety during this COVID-19 pandemic for healthcare staff are: compliance with the use of PPE, hand hygiene, working hours duration, risky procedures, and environmental factors.Keywords: healthcare workers, occupational safety, COVID-19, personal protective equipment
Comparison of Angiotensin-Converting Enzyme Inhibitor (ACEI) and Angiotensin Receptor Blocker (ARB) for Heart Failure Treatment in Congenital Heart Diseases with Left-to-Right Shunt Alit Utamayasa; Mahrus Ahmad Rahman; Teddy Ontoseno; Budiono budiono
The Indonesian Biomedical Journal Vol 12, No 1 (2020)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v12i1.997

Abstract

BACKGROUND: The angiotensin-converting enzyme inhibitors (ACEIs) have become the forefront of heart failure treatment for more than a decade. Currently, angiotensin receptor blockers (ARBs) are thought to have similar effectiveness. This study aimed to compare the impact of captopril, one of ACEI, and valsartan, one of ARB, on clinical presentation and echocardiographic, electrocardiographic, and chest x-ray improvement in patients with left-to-right shunt congenitalheart diseases.METHODS: This study used a double-blind randomized controlled trial of captopril and valsatran to children with left-to-right shunt congenital heart diseases who suffer from heart failure in the Dr. Soetomo General Hospital, Surabaya, Indonesia. Pediatric heart failure scores, echocardiography, electrocardiography (ECG), and chest photographs were examined at the beginning of the study and after 30 days of treatment.RESULTS: A decrease in pediatric heart failure scores were showed after the administration of ACEI (7.06±2.04 vs. 4.75±2.43; p<0.0001; 95% CI: −2.98 - 1.65); ARB (6.81±2.25 vs. 3.94±1.98; p<0.0001; 95% CI: −3.76 to 1.98). The echocardiography examination, an increase in left ventricular end-diastolic volume (LVEDV), left ventricular ejection fraction (LVEF), % fractional shortening (FS), and left ventricular (LV) dimension occurred after the administration of ACEI and ARB. The values also didn’t significantly differrent between the two groups. The ECG evaluation showed a decrease in heart rate frequency after the administration of ACEI (117.75±14.67 vs. 109.63±17.59; p=0.039; 95% CI: −15.78 to −0.46) and ARB (117.10±21.86 vs.108.6±20.66; p=0.006; 95% CI: −14.17 to −2.83).CONCLUSION: ARB showed better outcome in clinical condition, echocardiography, ECG, and chest radiographs.KEYWORDS: captopril, valsartan, heart failure, congenital heart disease, left to right shunt 
Co-Authors Adivia Cheries Dwiantoro Afika Danedea Pramitha Alit Utamayasa Fajra Arif Hatman Gery Morales Munthe Laksita Taffara Mahdy Mahrus A Rahman, Mahrus A Marsheila Harvy Mustikaningtyas Prima Ardiansah Surya Sacharissa Zerlina Tsarwah Thirafi Semedi, Bambang Pujo Teddy Ontoseno