Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal Indian Journal of Forensic Medicine & Toxicology Journal of Global Pharma Technology
Zainab J. Malik
Unknown Affiliation
Medicine & Pharmacology Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Effect of Castration on Bone Healing in Male Rabbit Model; Clinical, Histopathological and Radiological Study Ahlam J. AL-Khamas; Zainab J. Malik
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15593

Abstract

Twenty male rabbits were used in the current study. The rabbits were classified into two groups (castrated and un-castrated). Injected by solution consists from Ketamine HCL (40 mg /Kg/B.W/IM) and xylazine HCl (20mg /Kg B.W/IM). The first group was uncastrated while the second group was castrated and waiting one month. For both groups, at the middle of lateral aspect of the femoral region, a 5mm in diameter bore in the femoral bone was made by a medical drill device. The clinical signs showed some manifested such as pain, edema and fever in the castrated group more than the un-castrated group. The last clinical signs disappeared during two to three days in the un-castrated group and (5-7) days in the control group. Examination of radiological of both groups revealed reaction of the periosteal was begin at 2nd week in the second group while in the castrated group which started at the ending of 3rd week in the first group. The fracture was disappeared at 4th week in the second group. The bony mass was redesigned into the lamellar bone in 4th week in the second group, that characterized by adhesion of the bone with the external callus. Our study showed that the fracture healing morebest quantity and quality in the second group than in the first group. The histopathological examination showed osteoclast, osteoblast and the periosteal reaction started at (15-30) days after operation more in the second group than the first group. Moreover, the osteocytes is a presence in more in the uncastrated group than the first group.
Acceleration the Liver Regeneration by Hyperbaric Oxygen Therapy in Model Rabbit Zainab J. Malik
Journal of Global Pharma Technology Volume 10 Issue 07: (2018) July 2018
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

In this study, we were investigating the importance of therapy of the hyperbaric oxygenon the regeneration of liver. Sixteen mature rabbits of Iraqi breed were used. The animals divided equally into two groups (control and treated). The anesthetizing of animals was done byatropine sulphate (1mg /Kg B.W) intramuscularly; as premedication and 15 minutes later a mixture of xylazine hydrochloride (20mg /Kg B.W) and Ketamine hydrochloride (40 mg /Kg B.W) are giving intramuscularly. In control group the rabbits were anesthetized and preparation the site of operation was done in the upper part of abdomen.  Surgical incision made and exposure of fourth lobe of the live. The liver handling by thump forceps and the stitches was done on the lobe. Three knots were tied and we used dissecting scissors in order to cut the tied lobe just distal to the suture. After that the wall of abdomen was re approximated with a running 3-0 Polyglactinsuture, then the skin closed with a running 2-0 polyamide suture. While in treated group the same procedure that mentioned above with hyperbaric oxygen therapy was done. The clinical parameters included temperature, respiratory, and heart rates, were within acceptable limits post operatively in all animals in two groups. The intra-abdominal adhesions in different degrees of evaluations and occurred among liver, different organs and abdominal wall that more frequency in control group when compared with treated group. Histopathological Examinations was done by taken the liver biopsies on 15rd, and 30th, day postoperatively. The histopathological results of this study revealed that the liver regeneration more maturity in treated group than in control group.Keywords: Hyperbaric oxygen therapy, Liver, Rabbit, Regeneration.
Co-Authors Ahlam J. AL-Khamas