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All Journal Indian Journal of Forensic Medicine & Toxicology
Tabarek Mundher Noaman
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Public Health

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The Impact of OCA2 (rs1800407) and HERC2 (rs12913832) Gene Polymorphisms on Iris Color in a Sample of Iraqi People Tabarek Mundher Noaman; Abdul Kareem A. Alkazaz
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15698

Abstract

The study was directed in order to determine Single Nucleotide Polymorphisms (SNPs) (rs1800407 G>A)of OCA2 and (rs12913832 A>G) HERC2 genes and their association as a DNA marker with eye color in 60samples of Iraqi people. Samples were collected from College of Science / University of Baghdad and alsopeople from different areas of Baghdad, Iraq; during the two months period from September to November2020. These SNPs determination was carried out by using quantitative real-time polymerase chain reaction(qPCR) of blood samples. The results of rs12913832 genotype showed significantly differences (p<0.05) inthe green eye color group. A Survey of HERC2 gene SNP genotypes and allele frequencies in the black andgreen iris groups showed that there was a significant variation in the wild type (AA) and homozygous mutant(GG) genotype frequencies in (rs 12913832), while the SNP (rs1800407) of OCA2 concluded that gene mayhave a non-significant effect among a sample of this study comparing with green eye to black eye color.
Co-Authors Abdul Kareem A. Alkazaz