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All Journal Indian Journal of Forensic Medicine & Toxicology
Khalid O Mohammed Ali
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Public Health

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Estimation of IL-6 and IL-8 in the Urine and Serum of Children with Urinary Tract Infection Haneen A abed; Khalid O Mohammed Ali; Sinan B. Alrifai
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15773

Abstract

Urinary tract infection (UTI) is defined as the presence of bacteria in urine along with symptoms of infection.UTIs occurs in 1.1% of girls and 1.4% of boys in the first year of life. The aim of the study was to assessthe usefulness of measurement of pro-inflammatory interleukin (IL)-6 and IL -8 concentrations in the urineand serum of children with UTI. A total of Eighty serum sample and seventy tow urine sample have beencollected from children with urinary tract infection, Their age ranged between 33days- 12 years old, fifty sixchildren of the same age collected as controls .Urine and serum IL-6 and IL-8 concentrations of both groupswere measured and compared. Urine and serum concentrations of IL -8 were significantly higher in childrenwith UTI compared with controls group (P = 0.0001, P = 0.0002) respectively, while there was no significantdifferent in urine and serum concentration of IL-6 of children with UTI and controls group(P = 0.1199 , P=0.572) respectively. The results demonstrate that IL-8 is a good biomarker for urinary tract infection, whileIL-6 is not.
Co-Authors Haneen A abed Sinan B. Alrifai