Garuda - Garba Rujukan Digital

A simulation study of excitation coil design in single-sided mpi scanner for human body application Nurmiza Othman; Muhamad Fikri Shahkhirin Birahim; Wan Nurshazwani Wan Zakaria; Mohd Razali Md Tomari; Md Nor Ramdon Baharom; Luqman Hakim
Bulletin of Electrical Engineering and Informatics Vol 8, No 4: December 2019
Publisher : Institute of Advanced Engineering and Science

Magnetic particle imaging (MPI), a tomographic imaging method has been introduced for 3D imaging of human body with some potential applications such as magnetic hyperthermia and cancer imaging. It involves three important elements: tracer development using magnetic nanoparticles (MNPs), hardware realization (scanner using excitation and pickup coils), and image reconstruction optimization. Their combination will produce a high quality of image taken from any biological tissue in the human body based on the secondary magnetic field signal from the magnetized MNPs that are injected into human body. A homogeneous and adequate magnetic field strength from an excitation coil is needed to enhance the quality of the secondary signal. However, the complex surface topography of human body and physical properties of an excitation coil influence the strength and the homogeneity of the magnetic field generation at the MNPs. Therefore, this work focused on finding alternative design of excitation coil used in single sided MPI to produce up to 2 mT with high homogeneity of field distribution in the MNPs at the varied depth of 10 to 30 mm under the excitation coil. We proposed several designs with variation in physical properties and coil arrangement based on simulation study carried out by using Ansys Maxwell.

A simulation study of excitation coil design in single-sided mpi scanner for human body application Nurmiza Othman; Muhamad Fikri Shahkhirin Birahim; Wan Nurshazwani Wan Zakaria; Mohd Razali Md Tomari; Md Nor Ramdon Baharom; Luqman Hakim
Bulletin of Electrical Engineering and Informatics Vol 8, No 4: December 2019
Publisher : Institute of Advanced Engineering and Science

Magnetic particle imaging (MPI), a tomographic imaging method has been introduced for 3D imaging of human body with some potential applications such as magnetic hyperthermia and cancer imaging. It involves three important elements: tracer development using magnetic nanoparticles (MNPs), hardware realization (scanner using excitation and pickup coils), and image reconstruction optimization. Their combination will produce a high quality of image taken from any biological tissue in the human body based on the secondary magnetic field signal from the magnetized MNPs that are injected into human body. A homogeneous and adequate magnetic field strength from an excitation coil is needed to enhance the quality of the secondary signal. However, the complex surface topography of human body and physical properties of an excitation coil influence the strength and the homogeneity of the magnetic field generation at the MNPs. Therefore, this work focused on finding alternative design of excitation coil used in single sided MPI to produce up to 2 mT with high homogeneity of field distribution in the MNPs at the varied depth of 10 to 30 mm under the excitation coil. We proposed several designs with variation in physical properties and coil arrangement based on simulation study carried out by using Ansys Maxwell.

A simulation study of excitation coil design in single-sided mpi scanner for human body application Nurmiza Othman; Muhamad Fikri Shahkhirin Birahim; Wan Nurshazwani Wan Zakaria; Mohd Razali Md Tomari; Md Nor Ramdon Baharom; Luqman Hakim
Bulletin of Electrical Engineering and Informatics Vol 8, No 4: December 2019
Publisher : Institute of Advanced Engineering and Science

Magnetic particle imaging (MPI), a tomographic imaging method has been introduced for 3D imaging of human body with some potential applications such as magnetic hyperthermia and cancer imaging. It involves three important elements: tracer development using magnetic nanoparticles (MNPs), hardware realization (scanner using excitation and pickup coils), and image reconstruction optimization. Their combination will produce a high quality of image taken from any biological tissue in the human body based on the secondary magnetic field signal from the magnetized MNPs that are injected into human body. A homogeneous and adequate magnetic field strength from an excitation coil is needed to enhance the quality of the secondary signal. However, the complex surface topography of human body and physical properties of an excitation coil influence the strength and the homogeneity of the magnetic field generation at the MNPs. Therefore, this work focused on finding alternative design of excitation coil used in single sided MPI to produce up to 2 mT with high homogeneity of field distribution in the MNPs at the varied depth of 10 to 30 mm under the excitation coil. We proposed several designs with variation in physical properties and coil arrangement based on simulation study carried out by using Ansys Maxwell.

Magnetic particle imaging signal acquisition using second harmonic detection of magnetic nanoparticles Muhammad Mahadi Abdul Jamil; Abdulkadir Abubakar Sadiq; Muhammad Shukri Ahmad; Noordin Asimi Mohd Noor; Nur Adilah Abd Rahman; Nurmiza Othman
Indonesian Journal of Electrical Engineering and Computer Science Vol 15, No 1: July 2019
Publisher : Institute of Advanced Engineering and Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijeecs.v15.i1.pp221-229

This paper presents an approach for acquiring a magnetic particle imaging (MPI) signal, by utilizing the second harmonic detection of the magnetic nanoparticles tracers. An MPI signal with high signal-to-noise ratio (SNR) is crucial for high spatial resolution images that reveals the distribution of the tracers in a target area. Samples of Resovist and Perimag nanoparticles tracers were prepared in liquid and immobilised form, which were placed at some distances under the receiver coil of the single-sided MPI scanner. The samples were exposed to the excitation magnetic field generated at 22.8 kHz and a static gradient field generated with a direct current of 2 A. The non-linear magnetization response of the tracers for each spatial position is recorded in the form of voltage signal by a gradiometer pickup coil, with the second harmonic signal being extracted by a resonance circuit. The results obtained revealed that a sufficient signal from the tracers is recorded at up to 25 mm under the pickup coil, with Perimag samples inducing higher signals as compared to Resovist. The dependence of the DC gradient field on the second harmonic signal shows that the peak signal amplitude for Resovist and Perimag particles as ±5 mT and ±6 mT respectively. Additionally, the second harmonic signal amplitude increases exponentially with an increase in the excitation magnetic field. Thus, the results obtained shows the potential of this approach in acquiring high SNR MPI signals at low excitation frequency, which could be vital in reconstructing the contour images of the tracers, particularly in sentinel lymph node biopsy (SLNB) for breast cancer diagnosis.

Title

Found 4 Documents
Search

Abstract

Abstract

Abstract

Abstract

Title Search

Found 4 Documents Search

Abstract

Abstract

Abstract

Abstract

Title

Found 4 Documents
Search