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All Journal Indian Journal of Forensic Medicine & Toxicology Journal of Global Pharma Technology
Fadhel Omran Essa
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Medicine & Pharmacology Public Health

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Clinical Environment to Improve Operations, Medical and Surgical Applications: Study of Alternative Model of Carbon Connection of Diamond Alaa N. Hadi; Abbas H. Mugheer; Fadhel Omran Essa; Abdulameer K. Arat; Qasim S . Kadhim
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.16195

Abstract

Carbon Materials, especially interesting for practical application in the different areas of science andtechnique, by virtue of the numerous unique physical and chemical properties. The popular object ofresearches presently is allotropic modification of carbon – diamond that is examined as a classic modelcrystal. One of the most effective going near research of physical and chemical properties of diamondis his study by means of preliminary computer design of the studied dielectric descriptions. The authorsof the article examine the traditional and alternative mathematical models of the electronic configurationof nonpolar valency chemical connection of diamond. Results over of design of dielectric descriptionsof resilient electronic polarization of the examined material are brought on the basis of an offer physicalinterpretation of electronic structure.
Synthesis and Characterization of New4, 5-dihydrooxazole and 1H-imidazole-5(4H)-one Derivative and Study its Effects on some Antibacterial Fadhel Omran Essa
Journal of Global Pharma Technology Volume 11 Issue 01.
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (813.614 KB)

Abstract

New1H-imidazole-5(4H)-one derivatives have been prepared to start from the reaction of 2-phenyl-4H-1, 3-benzoxazine-4-one with tyrosine. The reaction of compound 1 with thionyl chloride produced 3-(4-hydroxyphenyl)-2-(4-oxo-2-phenylquinazolin-3(4H)-yl)propanoyl chloride2. Condensation of compound 2 with glycine afforded 2-(3-(4-hydroxyphenyl)-2-(4-oxo-2-phenylquinazolin-3(4H)-yl)propanamido)acetic acid3.The reaction of compound 3with acetic acid, acetic anhydride, and benzaldehyde derivatives yielded 3-(1-(4-benzylidene-4,5-dihydrooxazol-2-yl)-2-(4-hydroxyphenyl)ethyl)-2-phenyl-quinazolin-4(3H)-one derivatives 4a-e.Treatment of compound 4a-d with hydrazine hydrategave3-(1-(1-amino-4-benzylidene-4,5-dihydro-1H-imidazol-2-yl)-2-(4-hydroxyphenyl)-ethyl)-2-phenylquinazolin-4 (3H)- one derivatives 5a-d. The reaction of compound 5a-d with benzaldehyde derivatives resulted in the formation of 3-(1-(-4-benzylidene-1-(benzylidene amino)-4, 5-dihydro-1H-imidazol-2-yl)-2-(4 hydroxyphenyl) ethyl)-2-phenyl-quinazolin-4(3H)-one6a-6b.The structure of novel synthesized compounds were assured from IR, 1HNMR, and13CNMR spectra.Keywords: Phenylquinazolines, Imidazole, Benzylideneamino, Dihydrooxazole.
Co-Authors Abbas H. Mugheer Abdulameer K. Arat Alaa N. Hadi Qasim S . Kadhim