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All Journal Indian Journal of Forensic Medicine & Toxicology
Afnan I. Abdulwahab
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Public Health

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Preparation and Characterization of Silver Nanoparticle by Cordia myxa Extract and their Study Anticancer, Antioxidant, Antibacterial Activity Butheina A. Hasoon; Afnan I. Abdulwahab; Raghad Khwater Maeh; Khalida F. Al-azawi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.16625

Abstract

The ethanolic extract leaves of the Cordia myxa plant were used to prepare the biosynthesis of silvernanoparticles (Ag-NPs). The detection of Ag-NPs was done using UV, FTIR, and SEM. We evaluated theanti-bacterial property of ethanolic and nano extract against the growth of two types of pathogenic microbes:Gram –ve bacteria (E. coli) and Gram +ve bacteria (S. aureus). The antibacterial activity of the nano extractwas high. In vitro, extracts demonstrated strong antioxidant activity against DPPH at a concentration of0.8mg/ml. The MTT test was utilized to detect the cytotoxicity of nano extract against lung tumor, and theresults indicated that nano extract treatment significantly inhibited the growth of cells (A594 cell line) ina concentration dependent manner. The results indicate, nano extract is a particularly valuable source ofantiproliferative and cytotoxic agents.
Co-Authors Butheina A. Hasoon Khalida F. Al-azawi Raghad Khwater Maeh