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KUALITAS BELANJA DAERAH DAN HUBUNGANNYA DENGAN KINERJA PEMBANGUNAN DI PROVINSI BANTEN Sri Wahyuni; Bambang Juanda; Idqan Fahmi
JURNAL EKONOMI DAN KEBIJAKAN PEMBANGUNAN Vol 6 No 2 (2017): Jurnal Ekonomi dan Kebijakan Pembangunan
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (921.093 KB) | DOI: 10.29244/jekp.6.2.2017.16-31

Abstract

This study aims to analyze the relevant indicators of spending quality in measuring the quality of regional spending as well as the relationship between the quality of regional spending and the development performance of the regencies/cities of Banten Province. This study uses secondary data from the governance, financial and performance development of the districts/cities of Banten Province between 2009 – 2013. The Data are analyzed using Partial Least Squares Structural Equation Model (PLS–SEM) using SmartPLS software version 2.0 & SmartPLS version 3.0. The Results show that there are 21 indicators out of 40 indicators that are relevant in measuring the quality of the districts/cities spending in Banten Province. The change of the spending quality map from 2009 to 2013 shows that the quality of North Banten (Tangerang Regency, Tangerang City, Tangerang Selatan, Serang Regency, Serang City and Cilegon City) is better than South Banten (Pandeglang and Lebak). In addition, the estimation results from the model used indicate that the quality of the region spending of Banten Provinve has a positive relationship with the performance of development with the value of the indicator 0,678. Keywords : Development Performance, PLS-SEM, Spending Quality
Essential Oil and Ethanolic Extract of Curcuma Inhibits Mammae Tumors in Rats Induction by DMBA Akhmad Endang Zainal Hasan; Ekowati Handharyani; Sri Wahyuni
Jurnal Pharmascience Vol 9, No 1 (2022): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v9i1.13215

Abstract

Curcuminoids and xanthorizol are active components that may act as anticancer in the rhizome of Curcuma xanthorrhiza. The purpose of this study was to determine the content of the class of compounds in curcuma extract and essential oil using the phytochemical screening test method, the Folin-Ciocalteu method to determine the total phenolic content and the AlCl3 method for the total fentuconoid content. In addition, the activity of curcuma in inhibiting the influence of DMBA on the growth of breast cancer in rats was determined. Curcuma extract used is the result of extraction using 70% ethanol on an industrial scale. Total phenolic content and flavonoid extract of curcuma were determined by spectrophotometer. Inhibition testing of tumors formed due to DMBA induction was carried out by administering temulawak extract at doses of 35, 70, 140, 210 and 280 mg/kg body weight. Based on the phytochemical analysis, the ethanol extract of curcuma contained terpenoids, alkaloids, phenolic compounds and flavonoids. The results of the analysis of the ethanol extract of curcuma contained total phenols and flavonoids with concentrations of 42.96 mg GAE/g and 3.96 mg QE/g, respectively. The group that was given curcuma extract as the control group (p<0.05) had a significant difference. Based on the Mann-Whitney analysis, the third group with a dose of 140 mg/kg BW had the highest effect on tumor inhibition. The hope is that the development of curcuma extract into a standardized herbal medicine so that it can be used for the treatment of breast cancer can use the results of this research.