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All Journal Althea Medical Journal Indonesian Journal of Rheumatology
Santi Andayani
Department of Psychiatry, Faculty of Medicine, Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital
Medicine & Pharmacology

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Daily Living Performance in Schizophrenic Patients in Correlation with Positive and Negative Symptoms Nurul Amelia Rahayu Putri; Tuti Kurnianingsih; Santi Andayani
Althea Medical Journal Vol 7, No 2 (2020)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v7n2.1870

Abstract

Background: Schizophrenia is a global mental health problem. Patients experience problems in their daily-living performance. Positive and negative symptoms have been part of characteristics of schizophrenia that are absent in normal individuals, which include a distinctive fundamental distortion of thoughts and perception (positive symptoms) and loss of normal function and behavior (negative symptoms). This study aimed to explore the correlation between positive and negative symptoms and daily-living performance in schizophrenia. Methods: A correlative analytical study with a cross-sectional approach was conducted using secondary data from the Outpatient Clinic of the Mental Hospital of West Java Province. Data on socio-demographic characteristics were collected and positive and negative symptoms as assessed by Positive and Negative Syndrome Scale or Subscales (PANSS) were correlated with the activities of daily living (ADLs) and instrumental activities of daily living (IADLs), which were further analyzed by Spearman’s correlation test.Results: In total, 31 male schizophrenic patients aged between 24-45 years old. There was no significant correlation between ADLs dependency levels and both positive and negative symptoms. However, there was a significant correlation between IADLs function and positive symptoms and not with negative symptoms.Conclusions: Even though no correlation was identified between ADLs dependency levels with positive and negative symptoms, the ADLs and IADLs assessments should be considered as important tools for schizophrenic patients for rehabilitation to improve daily-living functioning.
Lupus Low Disease Activity State Associated with Lower Fatigue : Preeliminary Study Ryan Ardian Saputro; Santi Andayani; Stefanie Yuliana Usman; Laniyati Hamijoyo
Indonesian Journal of Rheumatology Vol. 11 No. 2 (2019): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ijr.v11i2.134

Abstract

Background: Systemic Lupus Erythematosus (SLE) is an autoimmune disease with heterogeneous clinical manifestations including fatigue. Previous studies aimed at proving the relationship between fatigue and SLE disease activity showed conflicting results. In 2015, Asia Pacific Lupus Collaboration (APLC) developed low disease activity criteria, named Lupus Low Disease Activity State (LLDAS). Patients who spend more time in LLDAS have significantly lower morbidity. This study aimed to evaluate the association between disease activity based on LLDAS and fatigue. Methods: This is a analytical cross-sectional study. Subjects were SLE patients at rheumatology clinic in Dr. Hasan Sadikin Hospital, Bandung during June-January 2018. Subjects were evaluated based on LLDAS criteria and divided into 2 groups: LLDAS and non-LLDAS. Fatigue status of the subjects was assessed with Fatigue Severity Scale (FSS). Results: A hundred and thirty-three subjects were included in this study, divided into 63 subjects in LLDAS group and 60 subjects in non-LLDAS group. Nineteen subjects (30.2%) in LLDAS group had fatigue and 39 subjects (65%) in non-LLDAS had fatigue. There was a significant association between LLDAS and fatigue (p< 0.001). Nonetheless, fatigue level in LLDAS group was still high since disease activity was not the only factor related to fatigue. Fatigue may be a distinct clinical manifestation of neuropsychiatric lupus and may be independent of lupus disease activity Conclusions: There was a significant association between LLDAS and fatigue showed by lower fatigue level was found in the LLDAS group than in the non-LLDAS group. Keywords: Systemic lupus erythematosus, disease activity, Lupus Low Disease Activity State, fatigue
Co-Authors Laniyati Hamijoyo, Laniyati Nurul Amelia Rahayu Putri Ryan Ardian Saputro Stefanie Yuliana Usman Tuti Kurnianingsih