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All Journal Althea Medical Journal Paediatrica Indonesiana
Armijn Firman
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Health Professions Medicine & Pharmacology

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Journal : paediatrica indonesiana

 1 
Role of multidetector spiral CT scanning for pulmonary embolism confirmation in a child with pulmonary hypertension: a case report Heda Melinda Nataprawira; Sri Endah Rahayuningsih; Nono Sumarna Afandi; Armijn Firman; Tan Siauw Koan
Paediatrica Indonesiana Vol 49 No 1 (2009): January 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (191.806 KB) | DOI: 10.14238/pi49.1.2009.54-8

Abstract

Pulmonary embolism (PE)  is  associated withconsiderable morbidity and mortality. Earlydiagnosis and prompt treatment  is  essential,  1 • 2however PE  is  rarely clinically diagnosed ortreated in children. Most clinically significant  PE  is  notrecognized antemortem. 3  While its diagnosis remainsa challenge  as  the signs and symptoms  can  often benon-specific,  an  accurate diagnosis  is  essential for themanagement  of  this disease. It  is  known  that  a numberof  non-invasive diagnostic tools are available for itsdetection nowadays. 1 • 2 .4  Even though multi-detectorspiral, also called helical,  CT  scanning  is  promisingand has  been  proven to be useful  in  diagnosing thiscondition with high sensitivity  and  specificity, 5  it  isunavailable even  in  referral hospitals  in  Indonesia.The  gold  standard,  pulmonary  angiography,  isconsidered  as  the procedure of choice to diagnose PE,but  unfortunately it  is  invasive. Failure to diagnose PEaccurately and promptly  can  result in excess morbidityand  death  due to pulmonary hypertension (PH) andrecurrent venous thromboembolic events. Conversely,unnecessary  anticoagulation  therapy poses a riskwithout any benefit.2
The occurrence of pulmonary hypertension in patients with thalassemia major Hasan Basri; Armijn Firman; Kusnandi Rusmil; Eddy Fadlyana
Paediatrica Indonesiana Vol 43 No 5 (2003): September 2003
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (240.461 KB) | DOI: 10.14238/pi43.5.2003.162-4

Abstract

Background The life of patients with thalassemia major dependson blood transfusions, while repeated blood transfusions may causeadverse effects such as iron deposition in various organs, includ-ing heart and lungs, which eventually increases the pulmonaryarterial pressure.Objective This study was proposed to know the occurrence ofpulmonary hypertension in patients with thalassemia major, mea-sured by echocardiography in the Thalassemia Clinic, Departmentof Child Health, Medical School, Padjadjaran University/HasanSadikin Hospital, Bandung.Methods A descriptive cross-sectional study was carried outon 30 patients with thalassemia major, aged 10-14 year-old whoreceived repeated blood transfusions. The study was conductedfrom April to May 2002. Subjects were examined right after ablood transfusion completed and the pulmonary arterial pres-sure was assessed using Doppler–echocardiography and 2-Dechocardiography.Results Twenty two out of 30 subjects showed pulmonary hyper-tension, with pulmonary arterial pressure ranged between 32.3 to46.2 mmHg. According to the age group, pulmonary hypertensionwas found in 12 out of 17 subjects aged 10-12 years old and 10out of 13 subjects aged 13-14 years old.Conclusion The occurrence of pulmonary hypertension in patientswith thalassemia major at Hasan Sadikin Hospital was 22/30 andseemed to increase with the age of the patients
Co-Authors Arifin Soenggono Eddy Fadlyana Farhatul Inayah Adiputri Gabriella Cafrina Gaga Irawan Nugraha Hasan Basri Heda Melinda Nataprawira Kusnandi Rusmil Nono Sumarna Afandi Sri Endah Rahayuningsih Tan Siauw Koan