hilda suherman
universitas harapan bangsa

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PENGARUH PENGGUNAAN VARIASI KONSENTRASI AVICEL PH-101 PADA FORMULA TABLET PREDNISOLONE hilda suherman
Viva Medika Vol 11 No 1 (2017)
Publisher : Universitas Harapan Bangsa Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (675.574 KB) | DOI: 10.35960/vm.v10i3.446

Abstract

Abstract Prednisolone is a steroid class drug that is used to treat certain types of allergies, inflammatory conditions, autoimmune disorders and cancer. Solubility of prednisolone is very difficult to dissolve in water causing problems in the absorption process so that the optimum formula is needed to form Prednisolone tablets that meet the requirements of the physical properties of tablets. The purpose of this study was to make the optimum formula with a combination of lactose excipients, avicel pH-101, and amprotab to obtain prednisolone tablets with good physical properties and dissolution. Prednisolone tablets made 7 formulas with a combination of lactose (A) Avicel PH-101 (B), and Amprotab (C), Formula I (100% A); Formula II (100% B); Formula III (100% C); Formula IV (50% A + 50% B); Formula V (50% A + 50% C); Formula VI (50% B + 50% C); Formula VII (33.33% A + 33.33% B + 33.33% C) in 2 batches. The method of making prednisolone tablets by direct printing. Testing of prednisolone tablets included the physical properties of tablets, weight uniformity, uniformity in size, hardness, friability, disintegration time, and dissolution test, and content determination. Keywords: optimization of formulas, tablets, Prednisolone, Simplex Lattice Design.
PENGARUH PENGGUNAAN VARIASI KONSENTRASI AVICEL PH-101 PADA FORMULA TABLET PREDNISOLONE hilda suherman
Viva Medika Vol 11 No 1 (2017)
Publisher : Universitas Harapan Bangsa Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (677.975 KB) | DOI: 10.35960/vm.v10i3.447

Abstract

Abstract Prednisolone is a steroid class drug that is used to treat certain types of allergies, inflammatory conditions, autoimmune disorders and cancer. Solubility of prednisolone is very difficult to dissolve in water causing problems in the absorption process so that the optimum formula is needed to form Prednisolone tablets that meet the requirements of the physical properties of tablets. The purpose of this study was to make the optimum formula with a combination of lactose excipients, avicel pH-101, and amprotab to obtain prednisolone tablets with good physical properties and dissolution. Prednisolone tablets made 7 formulas with a combination of lactose (A) Avicel PH-101 (B), and Amprotab (C), Formula I (100% A); Formula II (100% B); Formula III (100% C); Formula IV (50% A + 50% B); Formula V (50% A + 50% C); Formula VI (50% B + 50% C); Formula VII (33.33% A + 33.33% B + 33.33% C) in 2 batches. The method of making prednisolone tablets by direct printing. Testing of prednisolone tablets included the physical properties of tablets, weight uniformity, uniformity in size, hardness, friability, disintegration time, and dissolution test, and content determination. Keywords: optimization of formulas, tablets, Prednisolone, Simplex Lattice Design.
TINGKAT PENGETAHUAN PASIEN TENTANG SWAMEDIKASI OBAT hilda suherman
Viva Medika Vol 11 No 3 (2018)
Publisher : Universitas Harapan Bangsa Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (387.149 KB) | DOI: 10.35960/vm.v10i2.448

Abstract

Abstract Self-medication is a human effort to treat diseases or symptoms of minor ailments such as fever, cough, flu, pain and others without a doctor's prescription. In practice, limited knowledge of drugs and their use can be a source of medication errors (medication error). This research was conducted with a cross sectional descriptive research method. Data was collected through a validated questionnaire filling technique. A total of 300 respondents involved in this study were selected by consecutive sampling method from 3 pharmacies in the city of Purwokerto which were determined proportionally according to the population of each pharmacy. Data were analyzed by Chi-square test and Fisher's test used Statistical Product and Servicer Solution (SPSS) version 17. The results showed that the patient's knowledge level was 22.6% classified as poor, 48% classified as moderate, and 29.4% classified as good. The use of self-medication is 26.3% irrational and 73.7% rational. Based on the results of the study, it was found that the patient's level of knowledge was classified as moderate with a percentage of 48%. While self-administered rationality is classified as rational with a percentage of 73.7%. Keywords: Self-medication, Pharmacy, Knowledge, Rationality of drug use
PENGARUH FAKTOR USIA, JENIS KELAMIN, DAN PENGETAHUAN TERHADAP SWAMEDIKASI OBAT hilda suherman
Viva Medika Vol 11 No 3 (2018)
Publisher : Universitas Harapan Bangsa Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (405.492 KB) | DOI: 10.35960/vm.v10i2.449

Abstract

Abstract Self-medication is a human effort to treat diseases or symptoms of minor ailments such as fever, cough, flu, pain and others without a doctor's prescription. In practice, limited knowledge of drugs and their use can be a source of medication errors (medication error). This research was conducted with a cross sectional descriptive research method. Data was collected through a validated questionnaire filling technique. A total of 300 respondents involved in this study were selected by consecutive sampling method from 3 pharmacies in the city of Purwokerto which were determined proportionally according to the population of each pharmacy. Data were analyzed by Chi-square test and Fisher's test used Statistical Product and Servicer Solution (SPSS) version 17. The results showed that the patient's knowledge level was 22.6% classified as poor, 48% classified as moderate, and 29.4% classified as good. The use of self-medication is 26.3% irrational and 73.7% rational. Based on the results of the Chi-square and Fisher test, the level of knowledge is influenced by age, recent education, and occupation. While self-medication rationality is not influenced by gender, education and employment. Based on the results of the study, it was found that the patient's level of knowledge was classified as moderate with a percentage of 48%. While self-administered rationality is classified as rational with a percentage of 73.7%. Keywords: self-medication, pharmacy, rationality of drug use
GAMBARAN PIO SWAMEDIKASI APOTEKER DALAM PENATALAKSANAAN FLU hilda suherman
Viva Medika Vol 11 No 3 (2018)
Publisher : Universitas Harapan Bangsa Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (202.391 KB) | DOI: 10.35960/vm.v10i2.450

Abstract

Abstract Self-medication is a human effort to treat diseases or symptoms of minor ailments such as fever, cough, flu, pain and others without a doctor's prescription. In practice, limited knowledge of drugs and their use can be a source of medication errors (medication error). This research was conducted with a cross sectional descriptive research method. Data was collected through a validated questionnaire filling technique. A total of 300 respondents involved in this study were selected by consecutive sampling method from 3 pharmacies in the city of Purwokerto which were determined proportionally according to the population of each pharmacy. Data were analyzed by Chi-square test and Fisher's test used Statistical Product and Servicer Solution (SPSS) version 17. The results showed that the patient's knowledge level was 22.6% classified as poor, 48% classified as moderate, and 29.4% classified as good. The use of self-medication is 26.3% irrational and 73.7% rational. Based on the results of the study, it was found that the patient's level of knowledge was classified as moderate with a percentage of 48%. While self-administered rationality is classified as rational with a percentage of 73.7%. Keywords: Self-medication, Pharmacy, Knowledge, Rationality of drug use