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All Journal Jurnal Penelitian Kesehatan Suara Forikes Amerta Nutrition
Perez Wahyu Purnasari
Bagian Ilmu Kesehatan Anak, Fakultas Kedokteran, Universitas Islam Sultan Agung Semarang
Health Professions Medicine & Pharmacology Nursing Public Health Other

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Pengaruh Kombinasi Probiotik dan Zinc terhadap Berat Badan Tikus Malnutrisi Siti Thomas Zulaikhah; Perez Wahyu Purnasari
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 12, No 2 (2021): April 2021
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf12212

Abstract

Background: Single zinc supplementation has shown to be ineffective to reduce the national prevalence of malnutrition. Further research is needed in administration of combined probiotics and zinc supplementation on body weight in malnourished rats. Aim: This study is designed to assess effects of probiotics and zinc co-supplementation on body weight in malnourished rats. Methods: Experimental study with pre-and post-test control group design, 30 rats, aged 8 weeks, weighed 150-200g, were randomly divided into 5 groups. Group K(+), P1, P2, and P3 were given low calorie diet for 14 days to induce malnutrition. On the 15th day, all rats were weighed. The treatment was started on day 15 to 28, K(+) was still given low calorie diet, P1 was given probiotics and zinc combination, P2 was given probiotics, and P3 was given zinc. P1, P2, P3 were given standard diet. On the 29th day all the rats in each group were weighed. Results: Data were analyzed using paired sample t-test with obtained p-value of 0.000 (p 0,05). Hasil: Uji Paired sample t-test diperoleh p-value = 0,000 (p
The Effects of Probiotic and Zinc on Hemoglobin Levels in Malnourished Rats Perez Wahyu Purnasari; Citra Primavita Mayangsari; Conita Yuniarifa
Amerta Nutrition Vol. 5 No. 4 (2021): AMERTA NUTRITION
Publisher : Universitas Airlangga, Kampus C, Mulyorejo, Surabaya-60115, East Java, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v5i4.2021.341-346

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ABSTRACTBackgrounds:Iron supplementation has not been able to maximize the reduction of anemia in children. Iron consumption that is not sufficient for daily needs and low iron absorption and lack of diversity of food sources of iron are the main causes of anemia in children. The absorption ability of macro and micro-nutrients is strongly influenced by the histological features of the ileum. Improvements in the histological features of the ileum by administering probiotics and zinc in cases of malnutrition are expected to improve absorption function, so that absorption of nutrients, especially iron, can be betterObjectives: To assess the effect of probiotics and zinc on hemoglobin levels in malnourished rats.Methods: The experimental study, using 30 rats aged 8 weeks, body weight 180-200 g, divided randomly into 5 groups. Group N was given a standard diet, groups M, PZ, P, and Z were given a low calorie diet for 14 days to make malnourished. The treatment was started on day 15 to 28, group M was still given a low calorie diet, groups PZ, P, and Z were given a standard diet and supplementation. PZ group was given a combination of probiotics and zinc, P group was given probiotics, and Z group was given zinc. On the 29th day, all blood samples were checked for Hb levels using spectrophotometry.Results:There was a significant difference in hemoglobin levels between the malnourished group and the treatment group (p < 0.0001). Hemoglobin levels in probiotic group were significantly higher among the other treatment groups and the combination group indicated significantly lower hemoglobin levels.Conclusions: Probiotic and zinc administration significantly influence hemoglobin levels in malnourished rats.
Co-Authors Citra Primavita Mayangsari Conita Yuniarifa Siti Thomas Zulaikhah