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SA-15 Antibiotic Resistance Microbial Infection in Five Dogs in Bali I Putu Wira Adi Wibawa; IWY Semarariana; MPA Yunikawati; NPTE Sucitrayani; PS Dwipartha; AANGD Wisesa; PJ Sukariada; AANO Pujawan
Hemera Zoa Proceedings of the 20th FAVA & the 15th KIVNAS PDHI 2018
Publisher : Hemera Zoa

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Abstract

Antimicrobial Resistance is a global public health problem that is influenced by the use of antimicrobial agents in humans, animals and elsewhere. Abuse of antibiotics has increased the prevalence of human and animal microbioma resistance genes over the last 75 years (Pal et al, 2016). Antibiotic resistance occurs when bacteria are able to reduce or eliminate the effectiveness of drugs, chemicals or other agents designed to cure or prevent infection. Thus bacteria survive and continue to multiply causing more harm (Bisht et al 2009). A strain is resistant against an antibiotic if its minimal inhibitory concentration (MIC) is higher than for the corresponding parental wild-type strain (Martinez et al, 2015;Bengtsson-palme, 2017). As well as humans, pet animal like dogs that have certain medical conditions that are often prescribed antibiotics have a higher risk of infection with antibiotic resistant bacteria. Antibiotic resistance in dog or other pet animal causes very adverse effects such as treatment failure with antibiotics that can cause severe infections, complications,  increased mortality. Antibiotic resistance leads to extended treatment time leading to increased medical expenses. Another impact that is considered very dangerous is the zoonotic potential of resistant microbes that can be transmitted to humans. Infections that do not respond to antibiotics appropriately, should be suspected of having an antibiotic resistant microbial infection. Actibiotic sensitivity test is necessary in the selection and use of appropriate antibiotics for therapy.
Respon Imun Primer Ayam Petelur Pasca Vaksinasi Egg Drop Syndrome Gusti Ayu Yuniati Kencana; I Nyoman Suartha; I Putu Wira Adi Wibawa
Buletin Veteriner Udayana Vol. 9 No. 2 Agustus 2017
Publisher : The Faculty of Veterinary Medicine, Udayana University

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Abstract

This study was conducted to determine the primary immune response post vaccination using EDS inactivated vaccine polyvalent. The sample used was a commercial layer farm in the village of Tiga, regency of Bangli, Bali. A total of 25 layer which were14 weeks old vaccinated using EDS-76 inactivated vaccine containing polyvalent Newcastle disease antigen virus, infectious bronchitis and egg drop syndrome by intramuscularly injection. Examination of EDS antibody titer using serologic test by Hemagglutination Inhibition (HI) test. Egg drops syndrome antibody titer checked four times, once before vaccination, and every week for three weeks post-vaccination to see the immune responses. The average antibody titer then analyzed using an univariate of variance test followed by a test of Least Significant Difference, Duncan test and regression analysis. The result showed an increase antibody of EDS was significantly every week post vaccination. The average antibody titers of EDS are 22,6 HI unit at one weeks post vaccination, about 25,04 HI unit at two weeks post vaccination and 26,4 HI unit at three weeks post vaccination.