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All Journal Open Access Health Scientific Journal COMSERVA: Jurnal Penelitian dan Pengabdian Masyarakat Jurnal Sosial dan Sains Jurnal Farmasetis
Marisah Marisah
Universitas Singaperbangsa Karawang
Humanities Astronomy Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Library & Information Science Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary

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Metode Validasi Golongan Obat Beta Blocker dalam Plasma Darah Manusia Menggunakan Metode HPLC Andien Ravelliani; Hasna Nisrina; Lala Komala Sari; Marisah Marisah; Riani Riani; Annastya Eka Agustin; Faizal Auladi Rivianto
COMSERVA : Jurnal Penelitian dan Pengabdian Masyarakat Vol. 2 No. 1 (2022): COMSERVA: Jurnal Penelitian dan Pengabdian Masyarakat
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/comserva.v2i1.205

Abstract

Bisoprolol and atenolol are beta blockers that selectively act on 1 receptors in the heart. This drug is used for the treatment of hypertension. Hypertension is an event where there is an abnormal increase in blood pressure in the arteries on a continuous basis. The normal range for blood pressure is 120/80 mmHg. The writing of this review article reviews the effect of antihypertensive drug compounds in biological samples, namely on human blood plasma using HPLC methods. Based on the results of several journals that have been reviewed, it was concluded that the drug compounds bisoprolol and atenolol in human blood plasma obtained accurate results through these two instruments.
Identifikasi dan Isolasi Senyawa Glikosida Saponin dari Beberapa Tanaman di Indonesia Andien Ravelliani; Hasna Nisrina; Lala Komala Sari; Marisah Marisah; Riani Riani
Jurnal sosial dan sains Vol. 1 No. 8 (2021): Jurnal Sosial dan Sains
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (5020.518 KB) | DOI: 10.59188/jurnalsosains.v1i8.176

Abstract

Glikosida merupakan salah satu senyawa metabolit sekunder yang terdiri atas gabungan dua bagian senyawa, yaitu glikon dan aglikon. Saponin merupakan glikosida bagian aglikon yang termasuk kedalam golongan glikosida triterpena dan sterol. Saponin memiliki banyak kegunaan untuk kesehatan diantaranya, sebagai immunomodulator, antivirus, antitumor, antiinflamasi, antijamur, dan efek hipokolesterol. Senyawa glikosida saponin tersebar luas pada beberapa tanaman di Indonesia. Penulisan review artikel ini mengulas tentang keberadaan senyawa glikosida saponin pada beberapa tanaman yaitu Daun Binahong (Anredera cordifolia (Ten.) Steenis), Pelepah Pisang Uli (Musa paradisiaca L.), Herba Pegagan (Centella asiatica L. Urban), Daun Majapahit (Cresentia cujete), dan Daun Bungkus (Smilax rotundifollia). Metode yang digunakan dalam identifikasi dan isolasi senyawa glikosida saponin mulai dari esktraksi maserasi, skiring fitokimia dengan cara uji saponin dan uji pewarna Liebermann Burchard (LB), fraksinasi secara ECC (Ekstraksi cair-cair), metode pemisahan Kromatografi Lapis Tipis (KLT), dan metode pemisahan lainnya. Berdasarkan hasil dari beberapa jurnal yang telah ditelaah, diperoleh kesimpulan bahwa lima tanaman tersebut positif mengandung senyawa glikosida saponin.
Studi dan Tatalaksana Terkait Penyakit Cacar Monyet (Monkeypox) yang Menginfeksi Manusia Marisah Marisah; Indah Laily Hilmi; Salman Salman
Jurnal Farmasetis Vol 11 No 3 (2022): Jurnal Farmasetis: November 2022
Publisher : LPPM Sekolah Tinggi Ilmu Kesehatan Kendal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (136.967 KB)

Abstract

Cacar Monyet disebabkan karena virus monkeypox (Orthopoxvirus, Family Poxviridae) ditemukan pada tahun 1958 di Denmark. Di Indonesia, kasus monkeypox pertama telah diketahui bahwa satu warga Indonesia terkonfirmasi positif cacar monyet (monkeypox). Metode yang digunakan adalah metode komparatif, literature review dikumpulkan dari 11 sumber dengan kata kunci “Cacar Monyet” dan “monkeypox”. Gejala awalnya yaitu demam, sakit kepala, dan nyeri punggung serta otot, lemas, ruam. Saat ini, belum adanya pengobatan yang tepat dalam kasus ini, namun masih mampu diatasi. Maka, perlu adanya studi dan tatalaksana seperti informasi lebih lanjut terkait penyakit cacar monyet, artikel ini bertujuan untuk memaparkan studi dan informasi agar masyarakat lebih mudah memahami. Adapun data dan sumber tinjauan ini terbukti bahwa informasi yang berkaitan dengan cacar monyet (monkeypox) sangat terbatas.
Isolasi Senyawa Limonen pada Minyak Atsiri Menggunakan Metode Uji Hidrodestilasi, Destilasi Uap dan Destilasi Air-Uap Vriezka Mierza; Andien Ravelliani; Bismar Al Bara; Marisah Marisah; Nur Sa’diyyah
Jurnal Farmasetis Vol 12 No 1 (2023): Jurnal Farmasetis: Februari 2023
Publisher : LPPM Sekolah Tinggi Ilmu Kesehatan Kendal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (201.792 KB)

Abstract

Minyak atsiri merupakan suatu senyawa yang mudah menguap dan memiliki kelarutan yang rendah terhadap air, dapat diperoleh dari hasil ekstraksi daun, buah, kulit buah, kayu, bunga dan biji-bijian. Pada minyak atsiri terdapat salah satu senyawa monoterpen limonen yang biasanya dimanfaatkan sebagai bahan aditif makanan, kosmetik, perasa hingga aroma tambahan. Metode review article dilakukan melalui penelusuran di Google cendekia dengan mensortir 15 artikel terkait dan dipilih 5 artikel yang dianggap sesuai dengan topik yang diinginkan. Hasil isolat yang diperoleh kemudian dianalisis menggunakan GC-MS (Gas Cromatography and Mass Spectroscopy) untuk mengetahui jenis senyawa kimia yang terkandung beserta kadarnya.
Determinants of Diarrhea Self-Medication Behavior Among Urban Housewives in Bekasi, Indonesia Salman Salman; Marisah Marisah; Uway Wariah; Iha Nursolihah
Open Access Health Scientific Journal Vol. 7 No. 1 (2026): February 2026
Publisher : Griya Eka Sejahtera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55700/oahsj.v7i1.157

Abstract

Background: Self-medication is the practice of treating oneself independently. If it is done reasonably and rationally, you will get benefits, but if it is done in a bad way, there is the potential for unexpected side effects from treatment. Self-medication efforts for diarrheal diseases are often carried out by the community, considering that diarrheal diseases are included in the top 10 diseases every year in Indonesia. In 2019, Bantargebang District had the highest number of diarrhea cases, with a total of 1,610 cases. Ciketingudik sub-district had the highest number of diarrhea cases with 76 cases.Methods: This research used a quantitative cross-sectional design involving 229 homemakers with children aged 1–5 years in Ciketingudik Village, Bantargebang District, Bekasi City. The sample was selected using purposive sampling. Data were collected using a valid questionnaire to measure knowledge, attitude, environmental factors, the role of health workers, and self-medication behavior for diarrhea. Data were analyzed using univariate analysis and chi-square test with a significance level of p < 0.05.Results: The results showed that most respondents were aged 26–45 years, had a basic level of education, and were not formally employed. Statistical analysis showed that age, education, and employment were not significantly associated with self-medication for diarrhea. Conversely, knowledge, attitudes, environmental conditions, and the role of health workers were significantly associated with self-medication behavior. Respondents with good knowledge, positive attitudes, supportive environments, and active involvement of health workers were more likely to self-medicate appropriately for diarrhea.Conclusion: self-medication for diarrhea among homemakers is influenced by cognitive, behavioral, environmental, and health system factors rather than by demographic characteristics. Strengthening health education, improving environmental conditions, and enhancing the role of health workers are essential strategies for promoting safe and rational self-medication practices and reducing diarrhea-related health risks in the community.
Co-Authors Andien Ravelliani Andien Ravelliani Annastya Eka Agustin Bismar Al Bara Faizal Auladi Rivianto Hasna Nisrina Iha Nursolihah Indah Laily Hilmi Lala Komala Sari Nur Sa’diyyah Riani Riani Salman Salman Uway Wariah Vriezka Mierza