Dwi Hartanti
Department of Pharmaceutical Biology, Faculty of Pharmacy, Universitas Muhammadiyah Purwokerto, Purwokerto, Central Java, Indonesia

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Plant cyanogenic glycosides: an overview Dwi Hartanti; Arinda Nur Cahyani
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 5 No. 1 (2020)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v5i1.10047

Abstract

The cyanogenic glycosides have consisted of α-hydroxy nitrile aglycone and a sugar moiety that producing hydrogen cyanide (HCN) during the hydrolysis process. This HCN-producing property underlines the toxicity of the plants commonly associated with these compounds in humans and animals. However, new evidence shows that the toxicity of these compounds is lower than those theoretically caused by the equivalent released HCN. In order to provide a deeper understanding of cyanogenic glycosides, an overview of these compounds is given in this article. It covers the chemistry, distribution, biosynthesis, toxicity, determination, as well as extraction and isolation of the compounds.