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Deden Indra Dinata
Departemen of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Bhakti Kencana University, Soekarno Hatta 754, Bandung, 40286, Indonesia
Chemistry

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Flavonoids from the Roots of Amomum compactum Soland Ex Maton (Zingiberaceae) Deden Indra Dinata; Rani Maharani; Fauzan Zein Muttaqien; Unang Supratman; Mohamad Nurul Azmi; Yoshihito Shiono
Jurnal Kimia Valensi Jurnal Kimia VALENSI Volume 7, No. 2, November 2021
Publisher : Syarif Hidayatullah State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/jkv.v7i2.21599

Abstract

Amomum compactum Soland Ex Maton is one of the Zingiberaceae family plants which is the endemic plants from West Java, Indonesia. This study was aimed to determine the chemical structure of flavonoid compounds from n-hexane extract of A.compactum Sol. Ex Maton roots. Dried powder of the roots was extracted consecutively with n-hexane, ethyl acetate, and methanol solvents. Three flavonoids, 5-hydroxy-3,7,4`-trimethoxy kaempferol (1), 5-hydroxy-3,7,3',4'-tetra methoxy kaempferol (2) and 4'-hydroxy-3,5,7-trimethoxy kaempferol (3), have been isolated from the roots of A. compactum Sol. Ex Maton.  The chemical structures of compounds 1-3 were identified by spectroscopy data including infrared 1D-NMR, 2D-NMR and HRTOF-MS as well as by comparison with previously reported spectral data. Compounds 1-3 were isolated from this plant for the first time and showed free radical DPPH scavenging activity.
Co-Authors Fauzan Zein Muttaqien Mohamad Nurul Azmi Rani Maharani Unang Supratman Yoshihito Shiono