Ivon Sindu Wijaya
National Hospital Surabaya

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Confusion, difficulty concentrating, and slow response induced by ropinirole therapy in an elderly patient with secondary Parkinsonism: a case report Emilia Sidharta; Ivon Sindu Wijaya; Hanny Cahyadi
Jurnal Ilmiah Farmasi Vol. 16 No. 2 (2020): Jurnal Ilmiah Farmasi
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.vol16.iss2.art3

Abstract

Abstract  Background: Ropinirole is a therapy that is widely used in patients with Parkinson's disease or Restless Leg Syndrome (RLS). Some research journals show that the long-term use of ropinirole can cause side effects. But unfortunately, there are no published studies from Indonesia that show the side effects of ropinirole..Objective: To report a case of several side effects induced by ropinirole therapyMethod : Assessment methods used were time series data collection followed by causality analysis using Naranjo Scale. Results:  This case reports several side effects such as confusion, difficulty concentrating, and  slow response experienced by a 75-year-old elderly patient who consumed ropinirole 2 mg as a therapy for Secondary Parkinsonism. Before using ropinirole, the patient had used levodopa-benserazide, trihexyphenidyl, and pramipexole to overcome Parkinson's for more than 3 years. During the period no side effects occurred. Side effects occurred after ropinirole therapy was given to patients.  The analysis using Naranjo Scale shows a score of 6 which means Probable.  Conclusion: The aim of this study is to raise awareness for health workers, especially pharmacists in order to increase alertness in patients using long-term medications such as those with Parkinson's.Keywords: side effect, secondary parkinsonism, ropinirole, elderly