Endang Syamsudin
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Padjadjaran University, Bandung, Indonesia

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Analysis of gene polymorphisms TGF? rs 1058213 to cleft lip cases with or without a non-syndrome cleft palate in Riau Malay Ethnic Masrial Masrial; Yanwirasti Yanwirasti; Sumaryati Syukur; Endang Syamsudin
Journal of Dentomaxillofacial Science Vol. 3 No. 1 (2018): (Available online: 1 April 2018)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/jdmfs.v3i1.498

Abstract

Objective: This study aims to determine the role of gene polymorphism TGFα rs 1058213 in cases of cleft lip with or without cleft palate nonsyndrome in the Riau Malay tribe.Material and Methods: DNA extraction of venous blood and polymorphism TGFα rs 1058213 was assessed using the Restriction Fragment Length Polymorphism-PCR (RFLP-PCR) working method and followed by sequencing. Genotyping SNP rs1058213 in the TGFα gene was performed by the RFLP-PCR method in control and CLP NS patients. The data was assessed using the test statistic premises T-test difference test.Results: The total sample size included 68 samples consisting of 34 CLP NS samples and 34 control samples. The cases of CLP NS occurred more in men than women, 20 cases (59%) and 14 cases (14%), respectively.Conclusion: There was no significant difference between TGFα rs 1058213 gene polymorphisms in CLP NS and controls in the Riau Malay tribe.
Management of sinistra condyle fracture in emergency: case report Cahyadi Siauw; Asri Arumsari; Endang Syamsudin; Fathurachman Fathurachman
Journal of Dentomaxillofacial Science Vol. 3 No. 3 (2018): (Available online: 1 December 2018)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2685.44 KB) | DOI: 10.15562/jdmfs.v3i3.735

Abstract

Objective: Condyle fracture is a fracture that involves temporomandibular joint, resulting temporomandibular joint disorder. It often caused complications namely ankylosis and temporomandibular joint disorder. Trauma induced mandible fracture can leads to unilateral or bilateral condyle fracture.Method: Nine teen years old male came with mouth bleeding and pain on left lower jaw joint. Clinical examination showed laceration on right chin and left condyle fracture.Result: Management of patient to stitch laceration wound on chin region. Condyle fracture was treated conservatively using closed reduction method by arch bar and MMF rubber.Conclusion: Condyle fracture management needs a particular concern using closed method or conservative and open method or surgery. This present case chose closed method referring minimal displacement of condyle fracture.
Effectiveness of the application of bawang dayak (eleutherine palmifolia l. merr) extracts on healing proccess in the osteitis alveolar post tooth extraction through fibroblast examination, collagen density and amount of osteogenesis (experimental study) Fajar Rezandaru; Endang Syamsudin; Indra Hadikrishna; Vetnizah Juniantito
Journal of Dentomaxillofacial Science Vol. 5 No. 1 (2020): (Available online: 1 April 2020)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1222.936 KB) | DOI: 10.15562/jdmfs.v5i1.933

Abstract

Objectives: The aim of this study was to analyze the potential for topical administration of Eleutherine palmifolia (l.) merr extract gel in the healing proccess of wound with osteitis alveolar as a complication after tooth extraction in Sprague dawley mice by observing fibroblast cell area, collagen density, and amount of osteogenesis.Material and Methods: This study used a true experimental research method conducted on Sprague Dawley mice. Sample were divided into 3 groups, namely K1 (osteitis alveolar was not given any treatment), K2 (osteitis alveolar mice were given iodoform paste application every 3 days), and K3 (osteitis alveolar mice were given application of the extract gel Eleutherine palmifolia (l.) merr topically). On day 3, 5 and 10 necropsy was done and the tooth sockets in the form of soft tissue together with hard tissue was taken, then preparations were made and stained with masson trichrome to examined fibroblasts, collagen and osteogenesis.Results: Topical application of the extract gel Eleutherine palmifolia (l.) merr showed the mean value of fibroblasts area and collagen density and the amount of osteogenesis were comparable to iodoform paste in alveolar osteitis healing.Conclusion: this study is that the application of Eleutherine Palmifolia (l) merr extract gel has almost the same effectiveness as iodoform paste