Article Per Year (5 Year)
p-Index From 2020 - 2025
0.23
P-Index
This Author published in this journals
All Journal As-syifaa Jurnal Farmasi
Nurul Fadhillah Amrullah
Fakultas Farmasi Universitas Muslim Indonesia
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
UJI AKTIVITAS PENGHAMBATAN ENZIM α-GLUKOSIDASE EKSTRAK ETANOL BIJI BUAH ALPUKAT SANGRAI (Persea americana Mill.) SECARA IN VITRO St. Maryam Maryam; Asriani Suhaenah; Nurul Fadhillah Amrullah
As-Syifaa Jurnal Farmasi Vol 12, No 1 (2020): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (179.199 KB) | DOI: 10.33096/jifa.v12i1.619

Abstract

It is known that the seeds of avocado (Persea americana Mill.) are one part of the avocado widely used to treat various diseases, including diabetes. Based on the previous research, avocado seeds contain flavonoids with the potency as inhibitors of the enzyme α-glucosidase. The research aimed to determine the potency of ethanol extracted by meceration using 96% ethanol. The inhibitory activity was assayed using ELISA (Enzyme-Linked Immunosorbant Assay) reader measured at the wavelength of 405 with an acarbose comparator. The results showed that the ethanol extract of avocado seeds had an inhibitory activity included in the active category based on IC50 value of 34.300 µg/mL. Meanwhile, the acarbose had inhibition activity included in the very active category with an IC50 value of 0.253 µg/mL.
Co-Authors Asriani Suhaenah St. Maryam Maryam