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Effect of Ethanol Concentration on Antibacterial Activity of Bligo Fruit Extract (Benincasa hispida Thunb) to Salmonella typhi Mubarak, Fhahri; Sartini, Sartini; Purnawanti, Dia
Indonesian Journal of Pharmaceutical Science and Technology Vol 5, No 3 (2018)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (421.641 KB) | DOI: 10.15416/ijpst.v5i3.16444

Abstract

Bligo fruit (Benincasa hispida Thunb) is one of medicinal plants that used to cure typhoid fever which caused by Salmonella typhi bacteria. The aim of this research is to find ont the effect of ethanol concentration as a solvent from Bligo fruit (Benincasa hispida Thunb) extracts as an antibacterial, especially to Salmonella typhi. This simplicia was being extracted with 96% ethanol, 70% ethanol, and 50% ethanol by using maceration method for 3x24 hours. The antibacterial activity test was done by diffusion of agar method to the MHA medium by obserring the resistor zone which formed from 96% ethanol, 70% ethanol and 50% ethanol. The diametres that have been obtained are 6,815 mm for 96% ethanol, 25,223 mm for 70% ethanol while for 50% ethanol there is no resisten zone can be seen. From the result canbe conclude that the best concentration of ethanol that has a great potencial as resistor to Salmonella typhi bacteria is the Bligo fruit (Benincasa hispida Thunb) extracts of 70% ethanol.Key words: Bligo fruit (Benincasa hispida Thunb), Antibacterial, Salmonella typhi.
ISOLASI DAN AKTIVITAS ANTIMIKROBA AKTINOMYCETES DARI TANAH KARST TAMAN WISATA BANTIMURUNG ASAL MAROS SULAWESI SELATAN Fhahri Mubarak; Herlina Rante; Natsir Djide
As-Syifaa Jurnal Farmasi Vol 9, No 1 (2017): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (549.166 KB) | DOI: 10.33096/jifa.v9i1.226

Abstract

The increasing number of deaths caused by infection encourage researchers conduct early stage in the search for new antibiotics to resolve the issue. This study aims to isolate microbes aktinomicetes contained in karst areas of Bantimurung-tourist park district South Sulawesi province to see the antimicrobial inhibitory activity. The initial stage to get new antibiotics, researcher isolated, identified, characterized and tested the antimicrobial activity of isolates to be studied. One of microbes widely studied to be taken of its active compound is aktinomycetes. The research phase is actinomycetes isolation, isolates purification, and testing isolates antagonistic  actinomycetes  to see  whether  there  is a power resistor formed. From the results obtained 8 isolates  actinomycetes isolation, but only 6 isolates that can be grown back properly. Six of isolates  actinomycetes obtained, tested antagonist was done to see  the activity of inhibitory  power. Two of active isolateswas  obtained  that have  inhibitory  against  several  microbes  that P. aeruginosa and S. aureus which is then coded isolates of K21 and K32.
Effect of Ethanol Concentration on Antibacterial Activity of Bligo Fruit Extract (Benincasa hispida Thunb) to Salmonella typhi Fhahri Mubarak; Sartini Sartini; Dia Purnawanti
Indonesian Journal of Pharmaceutical Science and Technology Vol 5, No 3 (2018)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (421.641 KB) | DOI: 10.24198/ijpst.v5i3.16444

Abstract

Bligo fruit (Benincasa hispida Thunb) is one of medicinal plants that used to cure typhoid fever which caused by Salmonella typhi bacteria. The aim of this research is to find ont the effect of ethanol concentration as a solvent from Bligo fruit (Benincasa hispida Thunb) extracts as an antibacterial, especially to Salmonella typhi. This simplicia was being extracted with 96% ethanol, 70% ethanol, and 50% ethanol by using maceration method for 3x24 hours. The antibacterial activity test was done by diffusion of agar method to the MHA medium by obserring the resistor zone which formed from 96% ethanol, 70% ethanol and 50% ethanol. The diametres that have been obtained are 6,815 mm for 96% ethanol, 25,223 mm for 70% ethanol while for 50% ethanol there is no resisten zone can be seen. From the result canbe conclude that the best concentration of ethanol that has a great potencial as resistor to Salmonella typhi bacteria is the Bligo fruit (Benincasa hispida Thunb) extracts of 70% ethanol.Key words: Bligo fruit (Benincasa hispida Thunb), Antibacterial, Salmonella typhi.
Edukasi Jajanan Sehat Dan Deteksi Dini Boraks Menggunakan Bumbu Dapur Astuti Amin; Nursamsiar Nursamsiar; Syamsu Nur; Fitriyanti Sami; Megawati Megawati; Fhahri Mubarak; Noer Rahman; Imrawati Imrawati; Lukman Muslimin; Andi puanguce Paluseri
Jurnal Pengabdian Kefarmasian Vol 3, No 1 (2022): JURNAL PENGABDIAN KEFARMASIAN
Publisher : Jurusan Farmasi Politeknik Kesehatan Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/jpk.v3i1.2830

Abstract

Education About Healthy School Snacks and Early Identification of Borax Using SpiceNutrition for school-age children are a significant factor in developing small and medium-scale food businesses. Unfair competition in the food business encourages the addition of hazardous chemicals to extend the shelf life of foods such as borax and formalin. This community service aims to understand students, parents, and teachers about healthy snacks and how to identify borax content in food using spices (turmeric). This community service is carried out at Ali Imran Kindergarten, Rappocini District, Makassar. Forty students attended this counselling, 35 parents and eight teachers. This activity begins with the presentation about the importance of healthy snacks and the dangers of borax and formalin. A demonstration of the use of turmeric to detect the presence of borax was carried out in front of parents and teachers. In the end, they were allowed to practice. The results showed an increase in the ability of parents and teachers (100%) to identify borax in food using turmeric.Keywords : Borax, Healthy snack, Turmeric, CounselingKebutuhan siswa akan makanan dan jajanan merupakan faktor utama berkembangnya usaha makanan skala kecil dan menengah. Pesatnya perkembangan usaha makanan tersebut bukan tidak mungkin mendorong timbulnya persaingan antar pedagang yang kurang sehat termasuk penambahan bahan kimia berbahaya untuk memperpanjang masa simpan makanan seperti boraks dan formalin. Pengabdian masyarakat ini bertujuan untuk memberikan edukasi terhadap siswa, orang tua dan guru mengenai pentingnya jajanan sehat dan cara mengidentifikasi kandungan boraks dalam jajanan menggunakan bumbu dapur. Pengabdian ini dilakukan di Taman Kanak-kanak (TK) Ali Imran, Kecamatan Rappocini, Makassar. Penyuluhan ini diikuti oleh 45 orang siswa, 40 orang tua siswa dan 6 orang guru. Kegiatan ini diawali dengan pemaparan materi mengenai pentingnya jajanan sehat serta bahaya boraks dan formalin. Demonstrasi penggunaan kunyit (Curcuma domestica) untuk mendeteksi adanya boraks dilaksanakan di depan orang tua siswa serta guru dan di akhir kegiatan mereka diberikan kesempatan untuk mempraktikkan. Hasil penyuluhan menunjukkan adanya peningkatan kemampuan orang tua siswa dan guru untuk mengidentifikasi boraks dalam makanan menggunakan kunyit yang ditunjukkan dengan semua peserta (100%) berhasil mempraktikkan.Kata kunci: Boraks, Jajanan, Kunyit, Penyuluhan
Antibiotik Cefadroksil pada Pasien Infeksi Saluran Pernapasan Atas (ISPA) Fhahri Mubarak; Rahmad Aksa; Afrilia Nursal
Jurnal Ilmiah Kesehatan (JIKA) Vol. 3 No. 3 (2021): Volume 3 Nomor 3 Desember 2021
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v3i3.133

Abstract

Upper Tract Infection is an infection that occurs in the nasal cavity, sinuses, and throat. Some of the diseases included in this infection are colds sinusitis, tonsillitis and laryngitis. This study is to determine the profile of the use of cefadroxil drugs in ARI patients in several places. ARI (Acute Respiratory Infection) affects all ages, but babies and toddlers are the most susceptible to infection. This study used secondary data got from literature searches on the use of cefadroxil antibiotics in patients with ARI. Data taken as data on the percentage of the number of patients based on the type of age, type of work, type of education. The patient’s domicile based on the ward in several places. The results showed that from several journals, among them were male patients who were most affected by Acute Respiratory Infection (ARI). This was due to frequent activities outside the home. In general, the profile of the use of cefadroxil antibiotics in patients with acute respiratory infections (ARI) is in accordance with the guidelines from the WHO and the Ministry of Health 2005.
Identification of Antibiotic-Producing Isolates from the Soil of Pesantren Darul Aman Gombara, Makassar Fhahri Mubarak; Wahyu Hendrarti; Hamdayani Lance Abidin; Arfan Abu Bakar
Indonesian Journal of Pharmaceutical Science and Technology Vol 9, No. 3, 2022
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v9i3.32257

Abstract

One source of antibiotics-producing microorganisms that are now widely used as a treatment for infections comes from the soil. Soil is an excellent medium for the growth and development of various microorganisms. The search for new antibiotics is currently urgently needed, because their use is not following the instructions, causing disease resistance. This study aims to get antimicrobial-producing microbial isolates that can inhibit the test microbes and identify the type of isolates. The first stage of microbial isolation was the dilution of the soil sample from 10-1 to 10-5 using the method of pouring on Nutrient Agar (NA) and Potato Dextrose Agar (PDA) medium. It carried further testing of antimicrobial activity against several test microbes out. The results of the isolation got 4 isolates of bacteria and 4 isolates of fungi with different identification of each isolate. In the test microbe, Escherichia coli isolates that gave activity were isolates IB1, IB2, IB3. In the Staphylococcus aureus test bacteria, the isolate that produces activity is the isolate IB1, IB2, IB3, IB4, IJ2, Meanwhile, for the test fungus Candida albicans was inhibited by isolates IB1, IJ1, IJ2, IJ3 and IJ4.
Variasi Teknik Pengeringan Daun Tekelan (Chromolaena odorata L.) Mempengaruhi Aktivitas Antioksidan: Penelitian Laboratorium dengan Metode ABTS Utami, Yuri Pratiwi; Mubarak, Fhahri; Rahman, Nur Fausia
Health Information : Jurnal Penelitian Vol 15 No 2 (2023): Mei-Agustus
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36990/hijp.v15i2.775

Abstract

Tekelan (Choromolaena odorata L.) merupakan tanaman yang digunakan sebagai di masyarakat sebagai obat luka dan antioksidan. Penelitian ini bertujuan untuk mengetahui pengaruh variasi teknik pengeringan daun tekelan terhadap aktivitas antioksidan ekstrak etanol menggunakan metode ABTS. Hasil penelitian aktivitas antioksidan metode ABTS menggunakan beberapa variasi tehnik pengeringan simpilisia yaitu dikering anginkan, teknik pengeringan sinar matahari langsung, sinar matahari langsung tidak langsung dan oven suhu 50oC dengan pembanding menggunakan vitamin C. Hasil penelitian menunjukkan nilai IC50 berturut-turut 28,909 µg/mL, 22,984 µg/mL,10,645 µg/mL dan 27,639 µg/mL dengan nilai IC50 vitamin C sebagai pembanding yaitu 4,558 µg/mL. Kesimpulan dari penelitian ini adalah terdapat pengaruh variasi metode pengering terhadap penangkalan radikal bebas ABTS, aktivitas antioksidan dengan metode pengeringan menggunakan cahaya matahari secara tidak langsung memiliki aktivitas terbaik.
ANTIBACTERIAL ACTIVITY OF TEMBELEKAN LEAF (LANTANA CAMARA L.) EXTRACTS AGAINST ESCHERICHIA COLI AND STAPHYLOCOCCUS AUREUS Mubarak, Fhahri; Rante, Herlina; Putri, Pratami Yona
Journal Microbiology Science Vol 2, No 2 (2022)
Publisher : Fakultas Farmasi, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (210.422 KB) | DOI: 10.56711/jms.v2i2.831

Abstract

(Lantana camara L.) is one of the wild plants that can be used to treat various diseases such as skin diseases and diarrhea. The aim of the study to determine the antibacterial activity of ethanol extract of leaf (Lantana camara L.) can inhibit the growth of bacteria Escherichia coli and Staphylococcus aureus. This research was conducted in May 2019 at the Makassar College of Pharmacy. The phase of this research is weighing extracts, extract concentration variant manufacturing process and testing the antibacterial activity of the ethanol extract of tembelekan leaves. The analytical method used is the agar diffusion method. The results showed that the Tembelekan leaves taken from Tana Toraja Regency had a inhibitory effect on the growth of Escherichia coli and Staphylococcus aureus at concentrations of 5, 10 and 20%. The  inhibition zone formed in Escherichia coli bacteria was 8.61, 11.57 and 18.67 mm and in Staphylococcus aureus bacteria that was 9.42, 11.68 and 17.34 mm.
Peningkatan Mutu Abon Ikan dan Jabu Jabu Khas Desa Madello dengan Mesin Modern Awaluddin, Sri Prilmayanti; Rasdi , Rasdi; Mubarak, Fhahri; Haijal, Ahmad; Putri, Hera Nur; Muntasir, Muntasir
Yumary: Jurnal Pengabdian kepada Masyarakat Vol. 5 No. 3 (2025): Maret
Publisher : Penerbit Goodwood

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35912/yumary.v5i3.3557

Abstract

Purpose: to improve the quality and production of fish floss and jabu-jabu brand "KONYNYA" through the application of a spice grinding machine and multi-purpose drainer with a cylindrical model with a centrifugal system. Methodology: The methodology used in this devotion includes: Socialization, Training, Intervention and application of technology, Assistance and evaluation, Sustainability Results: The application of a spice grinding machine produces a smooth and homogeneous spice texture, and improves the taste of the product. The centrifugal system's multi-purpose cylindrical drainer has succeeded in reducing oil levels, thus improving the quality and hygiene of the "KONYNYA" brand of fish floss and jabu-jabu products typical of Madello Village. Conclusion: The implementation of a multi-purpose spice grinding machine and drainer with a cylinder model centrifugal system brand "KONYNYA" in Madello Village has been carried out effectively and on target. Limitations: This devotion only reached one partner, namely Konynya Madello Village. Therefore, it is necessary to involve similar partners or groups of MSME shredded producers in the local area to improve the quality of local superior products. Contribution: This devotion makes a significant contribution to increasing knowledge and skills in the production process, as well as improving quality to support local superior products. The implication of this research is increasing the competitiveness of local products in the market, which is expected to improve the welfare of local communities.
Intensifikasi Produk “Petani Hidroponik” dalam Integrasi Aquaponik di Yayasan Al Anshar Timor Timur, Makassar, Sulawesi Selatan Mubarak, Fhahri; Khairuddin, Khairuddin; Awaluddin, Sri Prilmayanti; Azis, Siti Yuki Oktafitriah; Reski , Reski; Padang, Dirgaraya Kala’
Yumary: Jurnal Pengabdian kepada Masyarakat Vol. 5 No. 3 (2025): Maret
Publisher : Penerbit Goodwood

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35912/yumary.v5i3.3718

Abstract

Purpose: To help the partner ‘Moreira Farm’ to solve the problem of efficient and effective hydroponic plant management and quality. Methodology: carried out at Moreira Farm in the Al Anshar East Timor Islamic Boarding School area, the method of applying innovation by increasing the quantity and quality of hydroponics by providing technological tools and innovations to streamline and increase the yield of hydroponic plants so that they are of higher quality than before. Results: the addition of innovation technology tools increases the results of hydroponic management with better quality. Community service has been carried out by involving partners Moreira Farm Pondok Pesantren Al Anshar East Timor by providing assistance in the form of innovation technology tools and materials. Conclusions: Moreira Farm Partnert experienced significant improvements and increases in hydroponic crop yields. Limitations: This service is limited to land conditions that still need to be revitalised. Contribution: This service is useful in the agricultural sector, namely Hydroponics, Aquaponics and Nutrient Film Technique.