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Hubungan Penggunaan Hair Styling terhadap Kejadian Dermatitis Seboroik pada Mahasiswa Laki-laki di Fakultas Kedokteran Universitas Sam Ratulangi Kalalo, Jonathan V. D.; Pandeleke, Herry E. J.; Gaspersz, Shienty
e-CliniC Vol 7, No 1 (2019): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v7i1.22451

Abstract: Seborrheic dermatitis is a type of papulosquamous dermatitis with predilection in areas with many sebaceous glands, scalp, face, and body. This disease is associated with immunological disorders, but ieven more with Malassezia. Seborrheic dermatitis can occur in all age groups, but is usually separated into two age groups: infants and adults. Seborrheic dermatitis has many precipitating factors, especially high oil levels and humidity. One of the trigger factors is the use of hair styling which triggers the oil production on the surface of scalp as well as hair. The occurence of excessive oil on the scalp and hair long time can cause dandruff and irritation. This study was aimed to determine the relationship between hair styling and the incidence of seborrheic dermatitis in male students at Sam Ratulangi University in Manado. This was an analytical study with a cross sectional design. Data were obtained by using questionnaires and anamnesis. The results showed that of the 25 respondents, 9 students had dandruff and 16 students did not. The chi-square test analyzing the relationship between hair styling and the incidence of seborrhoic dermatitis obtained a P value of 0.332. Conclusion: There is no significant relationship between hair styling use and the incidence of seborrheic dermatitisKeywords: hair styling, seborrheic dermatitis, male college studentsÂ Abstrak: Dermatitis seboroik adalah salah satu jenis dermatitis papuloskuamosa dengan predileksi di daerah yang banyak kelenjar sebasea, skalp, wajah dan badan. Penyakit ini sering dihubungkan dengan kelainan imunologi, namun lebih sering dihubungkan dengan jamur Malassezia. Dermatitis seboroik dapat terjadi pada semua kelompok usia, namun biasanya terpisah menjadi dua golongan usia yaitu bayi dan dewasa. Dermatitis seboroik memiliki banyak faktor pencetus, terutama kadar minyak yang tinggi dan kelembaban. Salah satu faktor pencetusnya ialah penggunaan hair styling berlebih yang memicu timbulnya minyak pada rambut. Munculnya minyak pada rambut yang terlampau lama dapat menimbulkan ketombe dan juga iritasi. Penelitian ini bertujuan untuk mengetahui hubungan pemakaian hair styling dengan kejadian dermatitis seboroik pada mahasiswa laki-laki Fakultas Kedokteran Universitas Sam Ratulangi Manado. Jenis penelitian ialah analitik dengan desain potong lintang. Data diperoleh berdasarkan kuesioner yang dibagikan dan anamnesis. Hasil penelitian mendapatkan total 25 responden terdiri dari 9 orang berketombe dan 16 orang tidak berketombe. Hasil uji korelasi chi-square terhadap hubungan antara penggunaan hair styling dengan kejadian dermatitis seboroik menunjukkan nilai P=0,332. Simpulan: Tidak terdapat hubungan bermakna antara penggunaan hair styling dengan kejadian dermatitis seboroikKata kunci: hair styling, dermatitis seboroik, mahasiswa laki-laki

Penyakit Adamantiades-Behcet Koinfeksi dengan Herpes Genital Korompis, Charly M. M.; Sengkey, Triomega F. X.; Gaspersz, Shienty; Niode, J.
Jurnal Biomedik : JBM Vol 10, No 2 (2018): JURNAL BIOMEDIK : JBM
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/jbm.10.2.2018.20092

Abstract: Adamantiades-Behcet (AB) disease is a rare multi-systemic inflammatory disorder with unknown cause. It is characterized by recurrent mucocutaneous ulcer in the mouth and genitalia, and mostly affects the age group of 20 to 30 ys. Genital lesion of AB must be differentiated from others caused by sexually transmitted disease, such as genital herpes. Co-infection of AB with genital herpes is very rare. We reported a male 72-year old, came with painful ulcers in the mouth and genital area since a week before visit. Symptoms were recurrent since three years ago. History of arthritis, recurrent headache, eye and skin lesions were denied. Patient was sexually promiscuous. Physical examination revealed multiple ulcers on the labium oris sized 0.5cm-1cm, irregular border, base covered by fibrin tissue, associated with erosion and crust. Multiple ulcers were also found on penile glans, sized 0.1x1x0.2 cm, irregular border, with pus and necrotic tissue. The ulcers were punched out. Pathergy test and anti HSV-1 IgM were negative meanwhile anti HSV-1 IgG, anti HSV-2 IgM as well as anti HSV-2 IgG were positive. Acyclovir 200mg 5x/day for five days, triamcinolone acetonide lotion bid for the mouth ulcer, NaCl 0,9% dressing applied tid for 30 minutes, and fucidic acid cream bid were given and the symptoms improved after 10 days. The prognosis was bonam for ad vitam and dubia for ad functionam and ad sanationam. Conclusion: The diagnosis of AB was based on the International Criteria for Behcet Disease, with a total score of 4 for the recurrent ulcer in mouth and genital area. The positive result of anti HSV-1 IgG, anti HSV-2 IgM and anti HSV-2 IgG supported the coinfection with genital herpes. This coinfection of AB and genital herpes was the first reported in Manado. Immunosenescence was a possible risk factor of the recurrent genital herpes. Symptomatic and antiviral treatment improved the symptoms with possible recurrent genital herpes.Keywords: Adamantiades-Behcet, genital herpes, coinfectionAbstrak: Penyakit Adamantiades-BehÃ§et (AB) merupakan kelainan inflamasi multisistemik yang tidak diketahui penyebabnya dengan manifestasi mukokutan tersering berupa ulkus berulang pada mulut dan genital. Penyakit ini terutama terjadi pada usia 20-30an. Lesi genital pada AB perlu dibedakan dengan ulkus genital akibat infeksi menular seksual termasuk herpes genitalis. Koinfeksi AB dan herpes genitalis jarang terjadi. Kami melaporkan kasus seorang laki-laki, usia 72 tahun, dengan keluhan luka di bibir dan kelamin yang nyeri sejak 1 minggu lalu, bersifat hilang-timbul selama 3 tahun terakhir. Riwayat nyeri sendi, sakit kepala berulang, serta kelainan kulit disangkal. Terdapat riwayat promiskuitas yang tinggi. Pada pemeriksaan fisik di regio labialis oris ditemukan ulkus multipel, diameter Â±0,5-1 cm, tepi tidak teratur, dasar tertutup jaringan fibrin, dengan erosi dan krusta. Di regio glans penis ditemukan ulkus multipel, ukuran bervariasi Â± 1x2x0,2cm, tepi tidak teratur, dasar tertutup pus dan jaringan nekrotik, terdapat punch out dan erosi. Tes patergi negatif. Pemeriksaan anti HSV-1 IgM (-), anti HSV-1 IgG (+), anti HSV-2 IgM dan IgG (+). Terapi asiklovir 5 x 200 mg/hari selama 5 hari, salep triamsinolon asetonid 2 kali oles, kompres terbuka NaCl 0,9% 3 x30 menit/hari, krim asam fusidat 2 kali oles, memberikan perbaikan klinis setelah 10 hari pengobatan. Prognosis quo ad vitam bonam, quo ad functionam, quo ad sanationam ad dubia. Simpulan: Pada kasus ini, diagnosis AB ditegakkan berdasarkan International Criteria for Behcet Disease yaitu ditemukannya ulkus berulang di mulut dan di genital, masing-masing mendapat nilai 2, sehingga nilai total ialah 4. Ditemukannya anti HSV-1 IgG, anti HSV-2 IgG dan IgM positif, menunjang diagnosis tambahan herpes genital (rekuren). Koinfeksi AB dengan herpes genital baru pertama kali dijumpai di Manado. Keadaan immunosenescence kemungkinan menjadi faktor pencetus terjadinya rekurensi herpes genital. Pasien sembuh dengan terapi simtomatis dan antivirus, meskipun kemungkinan rekurensi dapat terjadi lagi.Kata kunci: Adamantiades-Behcet, herpes genital, koinfeksi

PSORIASIS VULGARIS PADA BAYI Gaspersz, Shienty; Pandaleke, Herry E. J.
Jurnal Biomedik : JBM Vol 6, No 1 (2014): JURNAL BIOMEDIK : JBM Maret 2014
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/jbm.6.1.2014.4166

Abstract: Psoriasis may begin at any age but most often after puberty and only about 2% occurs in less than 2 years of age. The age of onset plays an important role because early onset psoriasis accompanied by a psoriasis family history is more severe and has a tendency to relapse. The treatment for mild psoriasis is topical and phototherapy. The first-line treatment is topical emollient, glucocorticoids, and vitamin D3 analog. We reported a case of a 3-month-old female infant presenting erythematous plaques with scales on scalp, face, neck, chest, tummy, armpit, back, buttock, and groin accompanied with irritability that had occured for a week. The Psoriasis Area Severity Index score (PASI) was 7% and laboratory examinations were within normal limits. Treatment with topical desonide 0.05% for 1 week did not result in any improvement. The treatment was changed to topical mometason furoat 0.1%. After 7 weeks of therapy, the plaques became flattened and less pigmented, and the PASI score decreased to 0.9%.Keywords: psoriasis vulgaris, infantÂ Â Abstrak: Usia awitan psoriasis bervariasi dari bayi hingga usia lanjut, namun sebagian besar timbul setelah pubertas dan hanya sekitar 2% terjadi pada usia kurang dari 2 tahun. Usia awitan perlu diketahui karena semakin dini usia awitan disertai adanya riwayat keluarga dengan psoriasis, perjalanan penyakit akan makin berat dan makin sering kambuh. Pilihan pengobatan pada psoriasis ringan (< 10%) ialah pengobatan topikal dan fototerapi. Pengobatan topikal lini pertama ialah emolien, glukokortikoid, dan analog vitamin D3. Kami melaporkan seorang bayi perempuan berusia 3 bulan yang datang dengan plak eritematosa, berbatas tegas, ukuran bervariasi, dengan skuama pada kepala, wajah, leher, dada, perut, ketiak, punggung, bokong, dan selangkangan, disertai rewel sejak 1 minggu lalu. Perhitungan Psoriasis Area Severity Index (PASI) 7%. Pemeriksan laboratorium masih dalam batas normal. Pasien diterapi dengan krim desonide 0,05%, namun setelah 1 minggu tidak terdapat perbaikan yang memuaskan, sehingga diganti dengan krim mometason furoat 0,1%. Setelah 7 minggu menggunakan mometason furoat, bercak merah yang awalnya meninggi menjadi hipopigmentasi dan mendatar serta perhitungan PASI menjadi 0,9%.Kata kunci: psoriasis vulgaris, bayi

Pentingnya Manajemen Talenta Dalam Pendidikan (Studi Literatur) Lumapow, Harol R.; Gaspersz, Shienty; Panjaitan, Jehezkiel; Kerap, Truly Galancy; Hatibie, Mendy Juniaty; Oley, Maximillian Christian
Jurnal Pendidikan Indonesia Vol. 5 No. 12 (2024): Jurnal Pendidikan Indonesia
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/japendi.v5i12.6331

Manajemen talenta merupakan strategi penting dalam meningkatkan kualitas pendidikan dan daya saing institusi, terutama di tengah perubahan global yang cepat dan tantangan pengelolaan sumber daya manusia. Penelitian ini bertujuan untuk mengkaji peran manajemen talenta dalam mendukung pengembangan institusi pendidikan di Indonesia. Metode penelitian literatur (literature review) dengan pendekatan deskriptif-analitis digunakan dalam penelitian ini, dengan data yang diperoleh dari jurnal ilmiah, buku, dan laporan penelitian yang relevan. Hasil analisis menunjukkan bahwa manajemen talenta berperan dalam meningkatkan efektivitas institusi pendidikan melalui proses identifikasi, pengembangan, dan retensi SDM berbakat. Selain itu, penerapan manajemen talenta membantu institusi pendidikan menghadapi tantangan perubahan teknologi, meningkatkan profesionalisme tenaga pendidik, dan mendukung pencapaian tujuan strategis. Kesimpulannya, penerapan manajemen talenta yang terencana dan strategis menjadi kunci untuk meningkatkan kualitas pendidikan sekaligus menciptakan daya saing yang berkelanjutan.

Manajemen Supervisi Kepala Sekolah Dalam Implementasi Kurikulum Merdeka (Studi Literatur) Wullur, Mozes Markus; Gaspersz, Shienty; Panjaitan, Jehezkiel; Kerap, Truly Galancy; Hatibie, Mendy Juniaty; Oley, Maximillian Christian
Jurnal Pendidikan Indonesia Vol. 6 No. 1 (2025): Jurnal Pendidikan Indonesia
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/japendi.v6i1.6980

Penelitian ini bertujuan untuk menganalisis peran supervisi kepala sekolah dalam implementasi Kurikulum Merdeka melalui kajian literatur dari berbagai penelitian nasional. Fokus kajian meliputi strategi supervisi, kontribusi terhadap kualitas pembelajaran, serta tantangan yang dihadapi kepala sekolah dalam mendukung perubahan kurikulum. Kajian dilakukan dengan mengelompokkan temuan berdasarkan tema utama, membandingkan strategi supervisi, dan mengevaluasi kontribusinya terhadap pemahaman guru serta efektivitas pembelajaran. Hasil menunjukkan bahwa supervisi kepala sekolah berperan signifikan dalam meningkatkan pemahaman guru terhadap Kurikulum Merdeka, mendukung penerapan metode pembelajaran berbasis proyek, serta menciptakan budaya kolaborasi di sekolah. Strategi efektif meliputi kunjungan kelas, evaluasi berbasis data, pemanfaatan teknologi seperti Platform Merdeka Mengajar, dan kolaborasi dengan guru senior. Namun, keberhasilan supervisi dipengaruhi oleh konsistensi pelaksanaan dan ketersediaan infrastruktur teknologi. Kajian ini memberikan implikasi penting bagi teori dan praktik pendidikan dalam merancang supervisi yang adaptif dan inovatif. Keterbatasan penelitian meliputi kurangnya data kuantitatif yang lebih mendalam dan fokus yang terbatas pada konteks Indonesia. Penelitian lanjutan disarankan untuk mengeksplorasi dampak supervisi terhadap hasil belajar siswa dan penerapan strategi berbasis teknologi di berbagai wilayah.

Sporadic Coexistence of Multiple Trichoepitheliomas and Solitary Neurofibroma: Mimicking Brooke–Spiegler Syndrome Rivano Frits Henry Pandaleke; Shienty Gaspersz; Ferra Olivia Mawu; Tara Sefanya Kairupan
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 10 No. 3 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v10i3.1522

Background: The simultaneous presentation of multiple adnexal tumors and neural sheath tumors on the face typically heralds a genodermatosis, most notably Brooke–Spiegler syndrome (BSS) or neurofibromatosis type 1 (NF1). The sporadic, non-syndromic coexistence of these entities in the same anatomical region is a diagnostic pitfall that challenges the principle of parsimony. Case presentation: We report the case of a 24-year-old Asian female presenting with a 12-month history of 18 disseminated, skin-colored papules restricted to the centrofacial region, followed by the rapid development of a 3.0 cm solitary tumor on the right buccal region. Dermoscopic evaluation revealed a dichotomy in tumor morphology: the papules exhibited ivory-white backgrounds with multiple rosette signs and milia-like cysts, while the buccal tumor displayed a structureless pink pattern with absence of pigment networks. Detailed physical examination ruled out cutaneous stigmata of NF1. Histopathological analysis confirmed the diagnosis of multiple trichoepitheliomas and a solitary localized neurofibroma based on characteristic morphological features, including papillary mesenchymal bodies and mast cell presence. Immunohistochemistry was not utilized due to setting-specific resource limitations. Conclusion: This case underscores the potential for sporadic benign tumors to mimic syndromic phenotypes (phenocopies). It highlights the critical importance of recognizing key hematoxylin and eosin morphological markers and clinical signs to establish accurate diagnoses in resource-limited settings where molecular genetics and immunohistochemical staining are unavailable.

The Steel-Blue Peppering and Systemic Eosinophilia: Dermoscopic-Histopathological Correspondence of the Tyndall Effect in Generalized Fixed Drug Eruption William Yudistha Anggawirya; Shienty Gaspersz; Ferra Olivia Mawu; Thigita Aga Pandaleke; Anggi Anastasia Ursula Dien
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 10 No. 3 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v10i3.1538

Background: Generalized fixed drug eruption (GFDE) represents a severe and distinctive variant of delayed-type hypersensitivity, characterized by widespread, recurrent pigmentary lesions involving at least three anatomical sites. Its clinical presentation often mimics extensive lichenoid dermatoses or infectious conditions such as Hansen’s disease, leading to significant diagnostic delays, particularly in geriatric populations with polypharmacy. While dermoscopy offers a non-invasive bridge to histopathology, specific correlative studies in generalized cases remain scarce. Case presentation: We report the case of a 69-year-old male presenting with diffuse, well-demarcated, violaceous plaques affecting the face, trunk, extremities, and genitalia. The eruption demonstrated a pathognomonic acute latency, recurring at identical anatomical sites within six hours of re-exposure to an unprescribed analgesic cocktail. High-definition non-contact polarized dermoscopy identified two distinct morphological patterns: a brown starburst pattern with central clearing on the extremities and diffuse steel-blue peppering on femoral lesions. Notably, the patient exhibited a mixed immunophenotype characterized by marked eosinophilia (2,080 cells per microliter) and elevated total immunoglobulin E (2,295 IU per milliliter). Parasitic infection was rigorously excluded via negative stool examination and serology, and a Naranjo probability score of 10 confirmed a definite adverse drug reaction. Histopathological examination confirmed interface dermatitis with necrotic keratinocytes and marked pigment incontinence. Conclusion: This study illustrates that steel-blue peppering is a reliable dermoscopic surrogate for deep dermal pigment incontinence via the Tyndall effect. The discrepancy between high systemic eosinophilia and low tissue eosinophilia suggests a complex, potentially mixed-hypersensitivity phenotype in generalized cases, distinct from classic localized fixed drug eruption.

Sporadic Coexistence of Multiple Trichoepitheliomas and Solitary Neurofibroma: Mimicking Brooke–Spiegler Syndrome Rivano Frits Henry Pandaleke; Shienty Gaspersz; Ferra Olivia Mawu; Tara Sefanya Kairupan
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 10 No. 3 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v10i3.1522

Background: The simultaneous presentation of multiple adnexal tumors and neural sheath tumors on the face typically heralds a genodermatosis, most notably Brooke–Spiegler syndrome (BSS) or neurofibromatosis type 1 (NF1). The sporadic, non-syndromic coexistence of these entities in the same anatomical region is a diagnostic pitfall that challenges the principle of parsimony. Case presentation: We report the case of a 24-year-old Asian female presenting with a 12-month history of 18 disseminated, skin-colored papules restricted to the centrofacial region, followed by the rapid development of a 3.0 cm solitary tumor on the right buccal region. Dermoscopic evaluation revealed a dichotomy in tumor morphology: the papules exhibited ivory-white backgrounds with multiple rosette signs and milia-like cysts, while the buccal tumor displayed a structureless pink pattern with absence of pigment networks. Detailed physical examination ruled out cutaneous stigmata of NF1. Histopathological analysis confirmed the diagnosis of multiple trichoepitheliomas and a solitary localized neurofibroma based on characteristic morphological features, including papillary mesenchymal bodies and mast cell presence. Immunohistochemistry was not utilized due to setting-specific resource limitations. Conclusion: This case underscores the potential for sporadic benign tumors to mimic syndromic phenotypes (phenocopies). It highlights the critical importance of recognizing key hematoxylin and eosin morphological markers and clinical signs to establish accurate diagnoses in resource-limited settings where molecular genetics and immunohistochemical staining are unavailable.

The Steel-Blue Peppering and Systemic Eosinophilia: Dermoscopic-Histopathological Correspondence of the Tyndall Effect in Generalized Fixed Drug Eruption William Yudistha Anggawirya; Shienty Gaspersz; Ferra Olivia Mawu; Thigita Aga Pandaleke; Anggi Anastasia Ursula Dien
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 10 No. 3 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v10i3.1538

Background: Generalized fixed drug eruption (GFDE) represents a severe and distinctive variant of delayed-type hypersensitivity, characterized by widespread, recurrent pigmentary lesions involving at least three anatomical sites. Its clinical presentation often mimics extensive lichenoid dermatoses or infectious conditions such as Hansen’s disease, leading to significant diagnostic delays, particularly in geriatric populations with polypharmacy. While dermoscopy offers a non-invasive bridge to histopathology, specific correlative studies in generalized cases remain scarce. Case presentation: We report the case of a 69-year-old male presenting with diffuse, well-demarcated, violaceous plaques affecting the face, trunk, extremities, and genitalia. The eruption demonstrated a pathognomonic acute latency, recurring at identical anatomical sites within six hours of re-exposure to an unprescribed analgesic cocktail. High-definition non-contact polarized dermoscopy identified two distinct morphological patterns: a brown starburst pattern with central clearing on the extremities and diffuse steel-blue peppering on femoral lesions. Notably, the patient exhibited a mixed immunophenotype characterized by marked eosinophilia (2,080 cells per microliter) and elevated total immunoglobulin E (2,295 IU per milliliter). Parasitic infection was rigorously excluded via negative stool examination and serology, and a Naranjo probability score of 10 confirmed a definite adverse drug reaction. Histopathological examination confirmed interface dermatitis with necrotic keratinocytes and marked pigment incontinence. Conclusion: This study illustrates that steel-blue peppering is a reliable dermoscopic surrogate for deep dermal pigment incontinence via the Tyndall effect. The discrepancy between high systemic eosinophilia and low tissue eosinophilia suggests a complex, potentially mixed-hypersensitivity phenotype in generalized cases, distinct from classic localized fixed drug eruption.

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