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All Journal Jurnal Penelitian Pascapanen Pertanian Jurnal Pengembangan Manajemen, Bisnis, Keuangan dan Perbankan
Nurdiana Agustina
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Agriculture, Biological Sciences & Forestry Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Social Sciences

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INHIBITING ACTIVITY OF ANGIOTENSIN CONVERTING ENZYME-1 BY BEAN PROTEIN HYDROLYSATE GENUS PHASEOLUS Tejasari Tejasari; Faiqotul Aulia; Nurdiana Agustina
Jurnal Penelitian Pascapanen Pertanian Vol 18, No 2 (2021): Jurnal Penelitian Pascapanen Pertanian
Publisher : Balai Besar Penelitian dan Pengembangan Pascapanen Pertanian

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21082/jpasca.v18n2.2021.75-86

Abstract

Kidney bean (Phaseolus.vulgaris L. Chitra) and lima bean (Phaseolus lunatus L. Sweet) hydrolysates were obtained by alcalase and flavourzyme hydrolysis of the bean seed protein. Peptide in the bean hydrolysates, with hydrophobic amino acids had been studied for their inhibitory ACE-1 activity preventing transformation into ACE-2 that prevention hypertension. This study aimed to measure inhibitory ACE-1 activity of protein hydrolyzates from the bean Phaseolus genus spp. grown in Jember, and its solubility. The bean protein (19.8-20,2%) was extracted using isoelectric precipitation at pH 4-4,6. The extract were hydrolyzed at pH 8-9 for alcalase and pH 7 for flavourzyme, followed with inactivation at 80-85 o C. ACE-1 inhibitory activity was measured based on the amount of hippuric acid (HA) formed by the hydrolysis of Hippuryl-His-Leu (HHL) in spectrophotometry detection method (228 nm). The ultra chromatography evaluation showed that the protein hydrolysates of kidney bean contained higher hydrophobic amino acids (455.5 mg/g protein) compare to those of lima bean (350 mg/g protein). Protein hydrolysates of both beans from alcalase hydrolysis have higher ACE-1 inhibitory rather than those from flavourzyme. Protein hydrolysate from Phaseolus spp bean protein hydrolysis by alcalase, contain small molecular weight peptides (3.9-22.6 kDa) high ACE-1 inhibition ability (83 -88%), and therefore suggested as antihypertensive nutraceuticals. Highest solubility of protein hydrolysate resulted from alcalase hydrolysis of both beans were observed at pH 8-9, while those resulted from flavorzyme hydrolysis were at pH 7.
OPTIMALISASI ALOKASI ASET DI PASAR MODAL PADA INDUSTRI ASURANSI INDONESIA Nurdiana Agustina
PRISMAKOM Vol 19 No 1 (2021): PRISMAKOM
Publisher : Sekolah Tinggi Ilmu Ekonomi Yasa Anggana Garut

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Abstract

A mathematical formula strategy is needed to minimize investment management errors as the cause of the insurance industry failing to pay claims to customers. By adhering to the investment limits set by the regulator, prudent and optimal investment management must prioritize the allocation of assets to investment instruments with fixed income (money market) and low risk to meet the company’s definite obligations. Then, if there is a residual, it can be allocated to a variable income investment instrument (capital market) which has a high return and high risk to increase the company's income with the simplex method linear programming model. Based on the basic assumptions presented in PT Taspen’s 2020 RKAP (Persero) investment assets can be allocated to investment instruments in the capital market worth Rp. 30,603,568,822,753,- or as much as 29.29% of the total investment can be in the form of stocks with an allocation weight of 14.95 %, mutual funds with an allocation weight of 11.27%, bonds with an allocation weight of 50.0%, medium terms notes with an allocation weight of 5.0%, and KIK-EBA with an allocation weight of 18.79%. So it is expected that the return on investment on December 31, 2020 will reach Rp. 9,900,434,973,836,-.
Co-Authors Faiqotul Aulia Tejasari .