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CYNTIA GRACESELLA HUTAMI P
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Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health

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KO-KRISTAL DI BIDANG FARMASI : REVIEW JURNAL CYNTIA GRACESELLA HUTAMI P; Iyan Sopyan; Marline Abdassah
Farmaka Vol 14, No 1 (2016): Supplement
Publisher : Fakultas Farmasi, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (539.786 KB) | DOI: 10.24198/jf.v14i1.10883

Abstract

Active Pharmaceutical Ingredients (APIs) are developing rapidly, one of the recent development is cocrystal. Cocrystal is a crystalline structure composed of multicomponent, such as atom, ion, or molecule, that are bonded by non-covalent bond. Cocrystal is solid at ambient temperature in its pure form. Cocrystals are made by combining active ingredients with its coformer using variety of method, like solubilisation as well as grinding. Cocrystalization has proven to alter physicochemical properties of drugs, including solubility, dissolution, stability, compressibility, which also alter its bioavailability without the change on its pharmacological effects.
Co-Authors Iyan Sopyan Marline Abdassah