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Qing Ping Hu
College of Life Sciences, Shanxi Normal University, Linfen 041004, China
Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Control & Systems Engineering Decision Sciences, Operations Research & Management Earth & Planetary Sciences

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Antibacterial Activities and Mechanism of Action of Acetone Extracts from Rabdosia rubescens Li Ping Cheng; Qing Ping Hu
Aceh International Journal of Science and Technology Vol 4, No 1 (2015): April 2015
Publisher : Graduate Program of Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2053.444 KB) | DOI: 10.13170/aijst.4.1.2100

Abstract

The antibacterial activities and mechanism of action of acetone extracts from R. rubescens were reported in this paper. The results showed that 80% acetone extracts had both the highest contents of total phenolics and flavonoids. Acetone extracts showed better antibacterial activities against Gram-positive bacterial strains and there were no inhibitory effects found on tested Gram-negative bacteria. In addition, 80% acetone extracts from R. rubescens had relatively higher antibacterial activities with the lowest values of MIC and MBC at 2.5 mg/mL and 5 mg/mL against B. subtilis. The antibacterial mechanism of 80% acetone extracts against Bacillus subtilis might be described as disrupting cell wall, increasing cell membrane permeability, and finally leading to the leakage of cell constituents
Co-Authors Li Ping Cheng