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All Journal World Nutrition Journal IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN)
Diyah Eka Andayani
Universitas Indonesia
Health Professions Medicine & Pharmacology Public Health

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Journal : World Nutrition Journal

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Selenium in Hyperthyroidism Shiela Stefani; Lukman Halim; Diyah Eka Andayani; Fiastuti Witjaksono
World Nutrition Journal Vol. 3 No. 2 (2020)
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V03.i2.0004

Abstract

Introduction: Thyroid gland has the highest selenium content compare with other endocrine organs. Enzyme that catalyzing thyroid hormone activation, iodothyronine deiodinases, were identified as selenocysteine-containing proteins. Selenium levels in soil and rice consumed in Indonesia were lower than in several other countries, which can increase the risk of selenium deficiency.Methods: This is an article review of the current literatures published up to November 2018 about the role of selenium in hyperthyroid.Result: Several studies have shown that selenium supplementation can be beneficial in patients with Graves disease and autoimmune thyroiditis. Selenium has an important immunomodulatory effect, but the effects of selenium supplementation in hyperthyroid has not been conclude. Data regarding selenium intake, prevalence of deficiency, and the relationship between selenium and thyroid disease in Indonesia are limited. Various studies of selenium supplementation in thyroid disease provide controversial results, so there are no guidelines that include selenium as standard therapy hyperthyroid. Selenium supplementation can enhance the restoration of biochemical euthyroidism in Graves disease and was associated with a significant decrease in the levels of thyroid peroxidase antibodies in autoimmune thyroiditis.Conclusions: Micronutrients that play a role in thyroid hormone synthesis and maintain thyroid function in addition to selenium are iodine, iron, zinc, and vitamin A. By correcting the deficit of selenium, and meeting other micronutrient requirements may provide health benefits in patient with hyperthyroid.
Vitamin E and Vitamin C Intake Among Lactating Mothers In Jakarta Sheira Taflah Putri Handana; Diyah Eka Andayani; Ninik Mudjihartini
World Nutrition Journal Vol. 3 No. 1 (2019): Volume 03 Issue 1 Include Supplements Oral Presentation Abstracts of 14th Sympo
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V03.i1.0009

Abstract

Background and ObjectivesVitamin E is a lipid soluble vitamin which obtain only through diet. Vitamin E has many functions including antioxidant and well known to prevent lipid peroxidation in membrane cell. Vitamin C helps to regenerate vitamin E back into non radical. Vitamin E and C intake among vulnerable group such as lactating mother still uncleared especially in Jakarta. The aim of this study to determine level of vitamin E and C intake among lactating mothers in JakartaMethods60 lactating mothers aged 20–40 years old in 1–6 months postpartum were recruited on Grogol Petamburan and Cilincing Public Health Centre in Jakarta. This cross sectional study held from March 2019 until April 2019. Vitamin E and C dietary intake were collected with semi quantitative food frequency questionnaire. Descriptive analysis was used in this study.ResultsThis study showed that median value  of vitamin E intake was 6.50 (1.20-43.10) gram/day with 91.7% subjects does not meet vitamin E recommended daily intake (RDA) recommendation (19 gram/day), otherwise 70% vitamin C intake was above RDA recommendation (100 gram/day) with median value is 120.05 (23.0-479.2) gram/day.ConclusionVitamin E intake among lactating mothers in Jakarta was not adequate and far below RDA recommendation but vitamin C intake among lactating mothers in Jakarta was adequate and met RDA recommendation.
The Effect of Vitamin D Supplementation During Pregnancy on The Risk of Having Preterm Birth: An Evidence-based Case Report Intan Meilana; Diyah Eka Andayani
World Nutrition Journal Vol. 5 No. 1 (2021)
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V05.i1.0009

Abstract

Introduction: Preterm birth (PTB) is a major cause of neonatal morbidity and mortality. Pregnant women is one of the most vulnerable groups for vitamin D deficiency, that increase the risk of PTB. Vitamin D has the role of immunomodulator, anti-inflammatory, and transcription of genes involved in placental function. Research results on the correlation between vitamin D supplementation and PTB risk are still inconsistent.Objective: To observe the effect of oral vitamin D supplementation during pregnancy on the risk of PTBMethods: Advanced search for relevant literatures in PubMed, Cochrane, and Willey was conducted. After assessing the relevancy and eligibility, articles were selected and critically appraised.Results: There were three articles that relevant with the eligibility criteria and clinical questions, they were randomized controlled trial, meta-analysis and systematic review. Three studies found that oral vitamin D supplementation in the form of cholecalciferol during pregnancy had a significant reduction on the risk of PTB. A systematic review found that supplementation with combination of cholecalciferol and calcium carbonate may increase the risk of PTB. The different dosages, frequencies, and time of initiation limit the generalizations for efficacy and safety doses.Conclusion: Oral cholecalciferol supplementation during pregnancy reduces the risk of PTB. While supplementation with combination of cholecalciferol and calcium carbonate requires consideration. Further research is needed to find out about the dose, frequency, time of initiation, adverse events and effects of vitamin D when combined with other vitamins and minerals. Keywords: Pregnancy, vitamin D, vitamin D3, cholecalciferol, preterm birth, preterm labor.
Co-Authors Fiastuti Witjaksono Intan Meilana Lukman Halim Ninik Mudjihartini Sheira Taflah Putri Handana Shiela Stefani Yusi Deviana