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All Journal Medical Journal of Indonesia The Indonesian Biomedical Journal Molecular and Cellular Biomedical Sciences (MCBS) Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Amerta Nutrition World Nutrition Journal Narra J eJournal Kedokteran Indonesia The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Fiastuti Witjaksono
Department Of Nutrition, Faculty Of Medicine, Universitas Indonesia-Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Other

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Obesity: not just the scale problem Witjaksono, Fiastuti
Medical Journal of Indonesia Vol 19, No 3 (2010): August
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (247.905 KB) | DOI: 10.13181/mji.v19i3.552

Abstract

[No Abstract Available]
Selenium in Hyperthyroidism Shiela Stefani; Lukman Halim; Diyah Eka Andayani; Fiastuti Witjaksono
World Nutrition Journal Vol. 3 No. 2 (2020)
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V03.i2.0004

Abstract

Introduction: Thyroid gland has the highest selenium content compare with other endocrine organs. Enzyme that catalyzing thyroid hormone activation, iodothyronine deiodinases, were identified as selenocysteine-containing proteins. Selenium levels in soil and rice consumed in Indonesia were lower than in several other countries, which can increase the risk of selenium deficiency.Methods: This is an article review of the current literatures published up to November 2018 about the role of selenium in hyperthyroid.Result: Several studies have shown that selenium supplementation can be beneficial in patients with Graves disease and autoimmune thyroiditis. Selenium has an important immunomodulatory effect, but the effects of selenium supplementation in hyperthyroid has not been conclude. Data regarding selenium intake, prevalence of deficiency, and the relationship between selenium and thyroid disease in Indonesia are limited. Various studies of selenium supplementation in thyroid disease provide controversial results, so there are no guidelines that include selenium as standard therapy hyperthyroid. Selenium supplementation can enhance the restoration of biochemical euthyroidism in Graves disease and was associated with a significant decrease in the levels of thyroid peroxidase antibodies in autoimmune thyroiditis.Conclusions: Micronutrients that play a role in thyroid hormone synthesis and maintain thyroid function in addition to selenium are iodine, iron, zinc, and vitamin A. By correcting the deficit of selenium, and meeting other micronutrient requirements may provide health benefits in patient with hyperthyroid.
A diagnostic test for malnutrition in adults: mid-upper arm circumference towards body mass index: A literature review Fathiyyatul Khaira; Fiastuti Witjaksono; Diyah Eka Andayani
World Nutrition Journal Vol. 4 No. 2 (2021): Volume 04 Issue 2, August 2021
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V04.i2.0012

Abstract

Body mass index is commonly used for detecting malnutrition. At certain conditions, body mass index cannot be measured, so mid-upper arm circumference can be an alternative measurement for detecting malnutrition. Several studies have proposed the cut-off point of mid-upper arm circumference in adults along with its sensitivity, specificity, and area under the ROC curve (AUC). This article aims to describe the diagnostic test for malnutrition using the upper arm circumference in adults and summarize the results of the related studies.
Protein and iron intake adequacy among high school girls in Depok, Indonesia Meirina Khoirunnisa; Yoga Devaera; Umi Fahmida; Fiastuti Witjaksono; Erfi Prafiantini
World Nutrition Journal Vol. 4 No. 2 (2021): Volume 04 Issue 2, August 2021
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V04.i2.0004

Abstract

Introduction: Iron deficiency anemia is the most common type of anemia among adolescent girls. The prevalence of anemia among pregnant women increased from 2013 to 2018, and females age 15-24 years had the highest prevalence of anemia. Therefore, knowing the baseline status of protein and iron intake —particularly animal-sourced protein as the main source of heme iron—is important to design future intervention program. Thus, this study was aimed to assess the protein and iron intake adequacy of High School girls in Depok, Indonesia. Methods: 211 girls from Senior High School in Depok, Indonesia participated in this study. Subjects were selected using a multi-stage random sampling method. A questionnaire was administered to obtain general characteristics. Dietary intake data were obtained using a 3-day non-consecutive 24hr recall 1 weekend 2 weekdays interview. Anthropometric status was measured and calculated. Data were analyzed using IBM SPSS Statistics 20. Spearman’s correlation (significance p<0.05) was used to determine the factors related to protein and iron intake. Results: This population had inadequate intake of energy (97.2%), protein (59.7%), and iron (98.6%). However, intake of fat was higher than recommended in 59.2% of participants. Protein and iron intake were not correlated with age, father’s education, mother’s education, and the number of household member.
Protein Intake, Prognostic Nutritional Index and Quality of Life in Head and Neck Cancer Patients Undergoing Radiotherapy Andry Kelvianto; Fiastuti Witjaksono; Sri Mutya Sekarutami
The Indonesian Biomedical Journal Vol 11, No 1 (2019)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v11i1.570

Abstract

BACKGROUND: It has not been well understood whether the quality and quantity of protein intake could affect the quality of life. Quality of life is associated with nutritional status, but the usage of prognostic nutritional index (PNI) to reflect quality of life of head and neck cancer patients undergoing radiotherapy also still has not been widely studied.METHODS: A cross sectional study was performed in 61 head and neck cancer patient undergoing radiotherapy. The quantity and quality of protein intake were obtained using semiquantitative food frequency questionnaire (FFQ) which was analized by analyzed using Nutrisurvey 2007, PNI was obtained using a calculation of Onodera’s formula based on laboratory data of serum albumin and total lymphocyte count (TLC), and domains of quality of life were obtained from the interview of European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Core Questionnaire (QLQ-C30) and EORTC Quality of Life Head and Neck module (QLQ-H&N35) and then calculated to get each domain’s score on quality of life.RESULTS: Patient’s median of total protein intake was 1.42 (0.26-4.11) g/kg/day. The median of PNI was 45.9 (29.4- 54.2). Quantity of protein intake was significantly correlated with several symptoms domain of quality of life. PNI was also significantly correlated with one functional domain and two symptom domains of quality of life. This study did not show a significant correlation between quantity and quality of protein intake with PNI.CONCLUSION: PNI has the potential to reflect quality of life of head and neck cancer patients. Future studies might be beneficial to show the usage of PNI to reflect quality of life, especially involving the progressivity of quality of life.KEYWORDS: animal protein, chemoradiotherapy, cachexia, quality of life
Role of Lifestyle Modification through Dietary Changes to Endometrial Receptivity on Infertility Women and Obesity with Polycystic Ovary Syndrome Julianto Witjaksono; Fiastuti Witjaksono; Andhika A. Perdana
Indonesian Journal of Obstetrics and Gynecology Volume 9 No. 1 January 2021
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v9i1.1415

Abstract

Abstract Objective: To investigate the effect of lifestyle modification on endometrial receptivity of obese women with polycystic ovary syndrome using ultrasonography.Methods: This observational study was conducted at Dr. Cipto Mangunkusumo General Hospital Jakarta from August 2019 to May 2020. A total of 14 subjects were participated in this study. The subjects were advised to get nutrition counseling by nutritionist and then followed up the endometrial profiles for 6 months by ultrasonography.Results: A total 19 subjects were received nutrition counseling by Clinical nutritionist, but then, only 14 subjects were evaluated the endometrial study by Ultrasonography. There were several significant result between before and after treatment some subjects such as calories, body weight, body mass index, waist circumference (p<0.05) and type of the endometrial vascular zone, endometrium volume, and vascular flow index by ultrasonography (p<0.05). In this study, no significant results have been found on the correlation between dietary changes and changes in endometrial receptivity profiles.Conclusion: No significant correlation was observed between changes in anthropometrics and daily calorie intake with changes in endometrial vascular zones.Keywords: endometrial receptivity, obese, polycystic ovary syndrome, ultrasonography. Abstrak Tujuan : Untuk mengetahui pengaruh modifikasi gaya hidup pada reseptivitas endometrium perempuan obesitas dengan sindrom ovarium polikistik menggunakan ultrasonografi.Metode: Penelitian observasional ini dilakukan di Rumah Sakit Umum Cipto Mangunkusumo Jakarta dari Agustus 2019 hingga Mei 2020. Sebanyak 14 subjek berpartisipasi dalam penelitian ini. Semua subyek disarankan untuk mendapatkan konseling gizi oleh ahli gizi dan dilakukan observasi profil endometrium selama 6 bulan dengan ultrasonografi.Hasil: Sebanyak 19 subjek menerima konseling gizi oleh ahli gizi klinis, tetapi kemudian, hanya 14 subjek yang dievaluasi profil endometrium dengan Ultrasonografi. Ada beberapa hasil yang signifikan antara sebelum dan sesudah perawatan beberapa subjek seperti kalori, berat badan, indeks massa tubuh, lingkar pinggang (p<0,05) dan tipe zona vaskular endometrium, volume endometrium, dan indeks aliran vaskular dengan ultrasonografi (p <0,05). Dalam penelitian ini, tidak ditemukan hasil yang signifikan pada korelasi antara perubahan pola makan dan perubahan dalam profil reseptivitas endometrium.Kesimpulan: Tidak ada korelasi yang signifikan antara perubahan antropometrik dan asupan kalori harian dengan perubahan zona vaskular endometrium.Kata kunci: endometrium, obesitas, reseptivitas, sindrom ovarium polikistik, ultrasonografi
Correlation between Protein Intake, Fat Free Mass, and Total Lymphocyte Count with Quality of Life in Pulmonary Tuberculosis Patients Undergoing Intensive Phase Treatment in Pekanbaru, Riau Province Dewi Krisna Yunda; Fiastuti Witjaksono; Fariz Nurwidya
Molecular and Cellular Biomedical Sciences Vol 4, No 3 (2020)
Publisher : Cell and BioPharmaceutical Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21705/mcbs.v4i3.144

Abstract

Background: Malnutrition and tuberculosis (TB) have a bidirectional relationship, which interacts between each other. In chronic infection, there is an imbalance between protein degradation and protein synthesis which marked with the loss of fat-free mass (FFM). Malnutrition can cause the atrophy of the thymus gland resulted in the reduction of lymphocyte production. Malnutrition in TB patients will reduce the quality of life. On the other hand, a good quality of life will increase the treatment success rate and decrease the risk of morbidity and mortality. Materials and Methods: A cross-sectional study was conducted in 12 primary health centers (PHC) chosen randomly from 23 PHC in Pekanbaru, Riau Province. The random selection was performed by using simple random sampling (random number generator). Data were collected from May until July 2019. Samples were selected using a consecutive sampling method and 72 subjects fulfilled all research criteria. The interview was used to collect basic characteristic data, dietary intake data, and quality of life score. Anthropometric measurement (body weight, body height, and FFM) and laboratory examination (total lymphocyte count) were done.Results: Research showed median age subjects was 33 years old (18-59 years old). Most of the subjects were male (56.9%), had a middle level of education, low income, were active smokers with underweight nutritional status. More than 50% of subjects had low protein intake, low fat-free mass, normal lymphocyte count and had a good quality of life.Conclusion: There was a statistically significant correlation between fat-free mass with PCS (r=0.239, p=0.044), but not for protein intake and total lymphocyte count.Keywords: fat-free mass, protein, quality of life, total lymphocyte count, tuberculosis
Association Between Risk of Malnutrition and Surgical Outcome in Ovarian Cancer Patients Fitriyadi Kusuma; Mutiara Riani; Fiastuti Witjaksono
eJournal Kedokteran Indonesia Vol 9, No. 3 - Desember 2021
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (119.598 KB) | DOI: 10.23886/ejki.9.71.203-7

Abstract

Ovarian cancer is the fourth most cancer in Indonesia. Treatment of ovarian cancer is surgery. Malnutrition may complicate healing, so studying the association between malnutrition and surgical outcome in ovarian cancer patients is necessary. A cross-sectional study was conducted in Dr. Cipto Mangunkusumo General Hospital from July 2018 - March 2019. fromo 63 patients underwent surgery, four were excluded due to non-malignant ovarian pathology results. Parameters assessed were characteristic subjects and risk factors of malnutrition in ovarian cancer patients. Malnutrition was assessed using the Patient-Generated Subjective Global Assessment (PGSGA) and surgery factors assessed were the length of surgery, size of the tumor, and blood loss during surgery. The nutritional status was classified as well-nourished and malnourished. The receiver operating characteristic (ROC) curve is used to assess malnutrition, length of stay, size of the tumor, and blood loss during surgery. The result shows that the prevalence of malnutrition in ovarian cancer was 78% (moderate was 42.4% and severe was 35.6%), and the median length of stay was eight days. There is an association (chi-square test, p<0.05) between malnutrition and surgical outcome in ovarian cancer patients. Malnutrition is associated (chi-square test, p<0.05) with a length of stay and increased blood loss during surgery.
High-Protein Dietary Supplementation and Nutritional Status Improvement of Malnourished Patients in Hospital Care Marcellus Simadibrata; Fiastuti Witjaksono; Yohannessa Wulandari; Raja Mangatur Haloho; Rabbinu Rangga Pribadi; Murdani Abdullah; Aditya Rachman; Anthony Eka Wijaya; Batara Bisuk; Daniel Martin Simadibrata; Rizka Mutiara; Kaka Renaldi
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 22, No 2 (2021): VOLUME 22, NUMBER 2, August 2021
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (736.079 KB) | DOI: 10.24871/2222021147-153

Abstract

Hospital malnutrition is common in Indonesia and other developing countries. In Asia, the prevalence of hospital malnutrition ranges between 27-39%. The causes of malnutrition in hospital care include insufficient food intake and increased catabolic processes due to underlying causes such as metabolic disease, infection, and malignancy. Several studies have demonstrated that malnutrition increases the morbidity and mortality of hospitalized patients, prolongs hospital stay, and delays recovery. Therefore, healthcare providers must recognize malnutrition early by conducting nutritional screening and assessment to prevent worsening of malnutrition and administer the optimal nutritional therapy to patients. Apart from giving a standard diet, high-protein food supplementation in liquid form remains a suitable alternative for patients, especially since it is easily digestible. A high protein diet is associated with a better mortality rate, better weight gain, and improved SGA score in patients.
The Effect of Intermittent Fasting 5: 2 on Body Weight and Insulin Resistance among Obese Employees in Jakarta Anni Rahmawati; Fiastuti Witjaksono; Erfi Prafiantini
Amerta Nutrition Vol. 5 No. 2 (2021): AMERTA NUTRITION
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v5i2.2021.158-165

Abstract

Latar Belakang: Prevalensi penduduk dewasa di Indonesia yang obesitas mengalami peningkatan dari tahun ke tahun. Sementara itu, angka obesitas pada pekerja, terutama di perkotaan juga makin meningkat. Puasa intermiten dapat menjadi alternatif solusi dalam tatalaksana obesitas untuk menurunkan berat badan, sehingga parameter metabolik lainnya seperti resistensi insulin juga bisa menurun.Tujuan: Mengetahui efek puasa intermiten 5:2 terhadap perubahan berat badan resistensi insulin pada karyawan obesitas di JakartaMetode: Penelitian ini menggunakan rancangan uji klinis acak terkontrol. Sampel penelitian ialah karyawan di Jakarta yang  berusia 19-59 tahun,memiliki IMT ≥ 25 kg/m2, dan memiliki lingkar pinggang ≥ 90 cm. Sampel dibagi menjadi kelompok intervensi (n=25) dan kelompok kontrol (n=25). Kelompok intervensi diminta untuk berpuasa pada hari senin dan kamis selama 8 minggu, sementara kelompok kontrol melanjutkan pola makan seperti biasa. Tidak terdapat pembatasan kalori pada kedua kelompok.  Pengumpulan data melalui proses wawancara, pengukuran tubuh serta pemeriksaan laboratorium.  Analisis data untuk melihat perbedaan rerata antar kelompok dengan menggunakan uji t tidak berpasangan atau uji Mann-Whitney, sementara untuk melihat perubahan dalam kelompok menggunakan uji t berpasangan atau Wilcoxon.Hasil: Perubahan berat badan pada kelomok intervensi ialah -0,8kg (-5,1- 2,2), sementara perubahan berat badan pada kelompok kontrol -0,3kg(-7,9 – 2,8). Perubahan kadar HOMA-IR pada kelompok intervensi ialah -0,29 (-17,78 – 6,84), sementara perubahan kadar HOMA-IR pada kelompok kontrol -0,46 (-18,94 – 10,55). Tidak terdapat perbedaan bermakna rerata perubahan berat badan dan resistensi insulin pada kelompok yang berpuasa dibandingkan kelompok yang tidak melakukan puasa (p>0,05). Terdapat perbedaan berat badan pada kelompok intervensi dengan p = 0,026.Kesimpulan: Tidak terdapat perbedaan perubahan berat badan dan kadar HOMA-IR pada kelompok yang berpuasa dibandingkan kelompok yang tidak melakukan puasa, walaupun perbedaan berat badan pada kelompok intervensi turun bermakna. Perlu dilakukan promosi dan edukasi kesehatan  secara berkala untuk meningkatkan pengetahuan dan mengubah perilaku karyawan akan gizi seimbang sehingga dapat mencegah terjadinya obesitas serta penyakit metabolik terkait obesitas.
Co-Authors Aditya Rachman Aditya Rachman, Aditya Agus Rizal Ardy Hariandy Hamid, Agus Rizal Ardy Hariandy Agus Siswanto Akmal Taher Amanda Pitarini Utari Andhika A. Perdana Andrijono Andrijono Andry Kelvianto Anni Rahmawati Anthony Eka Wijaya Ari Wijayanti Asmarinah Batara Bisuk Daniel Martin Simadibrata Dewi Krisna Yunda Diyah Eka Andayani Diyah Eka Andayani E. Mudjaddid A. Siswanto Deddy N.W.Achadiono Hamzah Shatri Erfi Prafiantini Fajriani, Rosalina Fariz, Nurwidya Fathiyyatul Khaira Ferry Safriadi Fitriyadi Kusuma Githa Putri Puspita Sari Haloho, Raja Mangatur Harahap, Alida Roswita Imam Subekti Julianto Witjaksono Kaka Renaldi Kuntjoro Harimurti Lukman Halim Marcellus Simadibrata Marcellus Simadibrata Megantara, Marcelino A. Meirina Khoirunnisa Murdani Abdullah Murdani Abdullah Mustikarani, Dewi Mutiara Riani Mutiara, Rizka Muzellina, Virly Nanda Nasrun, Martina W. Nur Rasyid Ponco Birowo Rabbinu Rangga Pribadi Raja Mangatur Haloho Retno Asti Werdhani Rizka Mutiara Rudi Putranto Savira, Missy Shiela Stefani Simadibrata, Daniel Martin Singal, Anna Maurina Siti Setiati Sri Mutya Sekarutami Sri Wuryanti Suhendro Suwarto, Suhendro Susworo Susworo Sutanto, Krisadelfa Suzanna Immanuel Umi Fahmida Widi Atmoko Wistara, Sevita Sathya Wulandari, Yohannessa Yoga Devaera Yohannessa Wulandari