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Sudirman Sudirman
Technology Center of Industrial Nuclear Materials - BATAN Kawasan Puspiptek, Serpong 15314, Tangerang
Materials Science & Nanotechnology

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MODELING THE FORMATION OF POLYLACTIDE MICROSPHERES Indra Gunawan; Aloma K. K.; Sudirman Sudirman
Jurnal Sains Materi Indonesia Vol 8, No 2: FEBRUARI 2007
Publisher : Center for Science & Technology of Advanced Materials - National Nuclear Energy Agency

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (72.621 KB) | DOI: 10.17146/jsmi.2007.8.2.4780

Abstract

MODELING THE FORMATION OF POLYLACTIDE MICROSPHERES. Biodegradable polylactide microspheres have been developed from a dispersion solution of polylactide in chloroform with polyvinyl alcohol in water. The present paper focuses on developing an understanding of microspheres formation through simple dimensional analysis and principle of system similarity for microstructure observation of microsphere diameter formed. Theoretical correlation between microspheres diameter and agitation rate was derived with the concept of similarity. While the empirical correlation between Weber (We) number and microspheres diameter was derived from dimensional analysis of variables that is useful for prediction of microspheres diameter to support Holmium powder. The empiric equation of the microspheres diameter forming as a function of essential process parameters is: ln (dm/dp) = -4.81 + 0.593 ln We.
Co-Authors Aloma K. K. Indra Gunawan