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All Journal Nexus Pendidikan Kedokteran dan Kesehatan Nexus Biomedika
Fikar Arsyad Hakim
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Biochemistry, Genetics & Molecular Biology Education Health Professions Medicine & Pharmacology

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The Effect of Personality Traits and Stress on Life Satisfaction in Medical Student of Sebelas Maret University Aprillio Bagas Sriwisnu; Murkati .; Fikar Arsyad Hakim
Nexus Pendidikan Kedokteran dan Kesehatan Vol 5, No 1 (2016): Nexus Pendidikan Kedokteran & Kesehatan
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Introduction: Higher life satisfaction in medical students produce health services were better in the future. One of the determining factors in life satisfaction is a personality traits. Extrovert and introvert personality can be used as consideration in choosing a policy approach to the education system in favor of life satisfaction. Also, stress in the medical education is very common. The high stress causes a decrease in academic performance and life satisfaction. The level of life satisfaction is one indicator of success in an educational institution. This study aimed to determine the effect of personality type and stress to the level of life satisfaction FK UNS Physician Education students. Methods: This research was using descriptive analytic cross-sectional approach. The study was conducted at the Faculty of Medicine UNS. Respondents were students FK UNS from 2013 to 2015. A sample of 260 students selected using stratified random sampling based on year entrance and selected according to the student identification numbers. Measuring instruments were Perceived Stress Scale (PSS), Eysenck Personality Inventory (EPI) and the Satisfaction With Life Scale (SWLS). Students were gathered in a room then got explanation and welcomed to fill out the questionnaire independently. Furthermore, the data was performed normality test and then analyzed by Pearson correlation test, followed by multiple linear regression analysis (? = 0,05). Results: Pearson correlation test results (0.139) show there is a very weak positive correlation between extrovert personality traits with a level of life satisfaction (p = 0.025). While there is a strong (-0.656) negative relationship between stress and the life satisfaction (p < 0.00). There is no multicollinearity relationship between these variables. Conclusions: Stress has a strong negative correlation to life satisfaction after personality traits variable has been controlled Keywords: Stress, Personality Traits, Life Satisfaction, Medical Education
The Correlation between Inflammatory Cells Density and NF-kB Expression in Fibroinflammatory Nasal Polyps Krisnawati Intan Suwignyo; Dyah Ratna Budiani; Fikar Arsyad Hakim
Nexus Biomedika Vol 5, No 2 (2016): Nexus Biomedika
Publisher : Nexus Biomedika

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Introduction: Asian nasal polyps have more neutrophil-dominant type than Europeans (>50%), the difference of histopathology feature may develope because different etiopathogenesis so they need to treat differently. NF-kB is a transcription factor that plays an important role in corticosteroid resistance mechanism in nasal polyps, while corticosteroid is the first choice of medical treatment for nasal polyps. The aim of this research was to determined the correlation between inflammatory cells density and NF-kB expression in fibroinflammatory nasal polyps. Methods: This analytic observational study had cross-sectional design which was done on 15 paraffin embedded fibroinflammatory nasal polyps tissues from patients who had their first nasal polyps surgery and fixed with buffered formalin. The blocks were taken from Anatomical Pathology Department of RSUD Dr. Moewardi and quota sampling was used to collect the samples. Each samples was stainned using hematoxylin-eosin and NF-kB immunohistochemistry technique, both inflammatory cells and NF-kB nuclear positive were counted, then analyzed using Spearman correlation. Result: Coeficient correlation (r) between lymphocytes and nuclear NF-?B in this study was 0.129 (p = 0.647), plasma cells and nuclear NF-?B was 0.404 (p = 0.135), macrophages and nuclear NF-?B was 0.367 (p = 0.178), while neutrophils and nuclear NF-?B was 0.285 (p = 0.301). Conclusions: There is no significant correlation between inflammatory cells density and NF-?B expression in fibroinflammatory nasal polyps. Key Words: nasal polyps, nuclear NF-kB, inflammatory cells
Co-Authors Aprillio Bagas Sriwisnu Dyah Ratna Budiani Krisnawati Intan Suwignyo Murkati .