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All Journal Nexus Kedokteran Komunitas Nexus Biomedika
Nur Hafidha Hikmayani
Faculty of Medicine, Sebelas Maret University
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

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Hubungan Penggunaan Obat Nyamuk dalam Rumah Tangga dengan Kejadian ISPA pada Balita di Puskesmas Sibela Surakarta Sumayyah Syahidah; Sumardiyono .; Nur Hafidha Hikmayani
Nexus Kedokteran Komunitas Vol 1, No 1 (2012): Nexus Kedokteran Komunitas
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Background: Morbidity and mortality due to acute respiratory infection (ARI) in children under five years old is high. Contributing factors include air pollution caused by domestic use of mosquito coils and spray. Hazardous chemicals in both mosquito coils and spray can iritate respiratory tracts, thereby putting children at higher risk for infection. This research aims to examine whether domestic use of mosquito coils and spray is associated with the prevalence of ARI among children under five years at Puskesmas Sibela Surakarta. Methods: This was an observational study using case control design conducted from March to April 2012 at Puskesmas Sibela Surakarta. Forty subjects were sampled using fixed-disease sampling method. Parents of case group (20 children with ARI) and control group (20 children without ARI) were interviewed and asked to fill out specific questionnaires. Data were analyzed using ?2 test and odds ratio. Results: Twelve children with ARI were exposed to mosquito coils and spray at home. History of mosquito coils and spray exposure at home were only found in two children without ARI. Statistical analyses showed a significant relationship between ARI in children and domestic use of mosquito coils and spray (OR = 13,5, 95% CI 2,4 to 74,9, p = 0,001). Conclusions: There was a significant relationship between domestic use of mosquito coils and spray with prevalence of ARI among children under five years at Puskesmas Sibela Surakarta. Compared to children who lived in a house not using mosquito coils and spray, those who were exposed to mosquito coils and spray at home had 13.5 times higher the risk to get ARI. Keywords: ARI, Children Under Five Years, Mosquito Coils and Spray.
Pemberian Suplemen Branched Chain Amino Acids (BCAA) untuk Mengurangi Tingkat Kelelahan pada Mahasiswa Pendidikan Dokter Universitas Sebelas Maret Muhammad Abdulhamid; . Kiyatno; Nur Hafidha Hikmayani
Nexus Biomedika Vol 2, No 2 (2013): Nexus Biomedika
Publisher : Nexus Biomedika

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Background: Fatigue is a condition characterized by a decrease in work efficiency and endurance. BCAA capsule contains of three kinds of essential amino acids, those were leucine 2275 mg, isoleucine 1137.5 mg, and valine 1137.5 mg, each of which plays an important role in protein synthesis and energy system for activity. This study aimed to examine the effect of supplement administration of BCAA to reduce fatigue levels in medical students of Sebelas Maret University (UNS). Methods: This was an experimental research with pretest-posttest group design. It was conducted at Faculty of Medicine UNS on December 13th, 2012. Subjects (n=40) were randomly selected from list of current medical students at preclinical level. Subjects who had been fasting for eight hours, then, were randomly arranged into two groups: (1) control group whose fatigue levels were measured twice in resting condition at10-minute interval, and (2) treatment group whose fatigue levels were measured before and 10 minutes after BCAA administration. Fatigue referred to decreasing concentration determined by reaction time to light stimuli. Pretest-postest fatigue levels for each group were analyzed using paired sample t-tests, whereas posttest fatigue levels between the two groups were analyzed using independent sample t-test. Data analysis were performed using SPSS 17.0 for Windows. Results: Mean fatigue levels of control group at first and second measurement, each, were 270.115.3 and 255.510.9 millisecond. While mean fatigue levels of treatment group at pretest and after BCAA administration were 268.9 14.8 and 211.738.8 millisecond, consecutively. Analysis of paired sample t test of pretest-postest fatique levels in both groups, each, showed significant difference (p = 0.001 for control group and p < 0.001 for treatment group), while analysis of independent t test of posttest fatigue levels between the two groups showed that the posttest fatigue levels between the two groups also differed significantly (p <0.001). Conclusions: BCAA administration significantly reduced fatigue levels in medical students of UNS. Fatigue levels were significantly shorter in subjects administered BCAA supplement than those of control group who did not take BCAA supplement. Keywords: BCAA suplement, fatigue
Co-Authors . Kiyatno Muhammad Abdulhamid Sumardiyono . Sumayyah Syahidah