Raizulnasuha Binti Ab Rashid
Universiti Sains Malaysia

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

The effects of wound dressings on the dose at surface and depth of maximum dose (dmax) for photon and electron beam radiotherapy Raizulnasuha Binti Ab Rashid; Norhayati Dollah; Reduan Abdullah; Wan Nordiana W. Abd Rahman
Journal of Medical Physics and Biophysics Vol 4, No 1 (2017)
Publisher : Indonesian Association of Physicists in Medicine (AIPM/AFISMI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (533.222 KB)

Abstract

The presence of wound dressing at the patients’ skin surface during radiotherapy treatment may potentially alter the dose at surface and shift the dose distribution at depth. In this study, the effects of different types of wound dressing to the radiotherapy treatment were investigated. The dose measurement at surface and dmax were done using different energy of photon and electron beams at 100 cm source to surface distance (SSD). Markus parallel plate ionization chamber and solid water phantom were used to quantify the dose with the dressing types used are Alderm +Plus, Actisorb Plus 25, Gauze and Duoderm CGF Extra Thin. The results show increment of surface dose up to 93.9% by wet gauze for photon beams and around 21% of dose increase for electron beams. Effects of dressing to the the dose at dmax indicate shift of dose distribution towards surface with reduction of dose around 10 % in wet condition for photon beam and up to 35 % for electron beams. Significant changes in surface dose and dose at dmax due to the wound dressing indicate the presence of wound dressing during radiotherapy need to taken in account in calculating dose to the target.
Radiobiological evaluation of radiation cells survival based on linear quadratic and multi-target model Raizulnasuha Binti Ab Rashid; Wan Nordiana Rahman
Journal of Medical Physics and Biophysics Vol 7, No 1 (2020)
Publisher : Indonesian Association of Physicists in Medicine (AIPM/AFISMI)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Radiobiological model such as linear quadratic is widely used in clinical radiotherapy to predict the biophysical response of the tumour cell to the radiation. This study investigates the radiation cell survival using Linear Quadratic and Multi-Target model and their radiobiological parameters. The experimental works were conducted in-vitro using HeLa cells that were irradiated using photon and electron beams of different energy. Cells irradiation were performed in full scatter condition and exposed to radiation doses ranges from 1 to 10 Gy. Clonogenic assay is used as an endpoint to obtain the cell survival curves which later be fitted with linear quadratic and multi-target model. The results demonstrate that Multi-target model produce the fitting curves that are closed to the experimental data compare to linear quadratic model especially at high doses. Parameter analysis from both models indicates more biological damage inflicted by high energy electron beam. Correlation between the experimental cell survival data and radiobiological model analysis suggesting that radiobiological model could be applied in analysing cells’ radiation survival and damage