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D Hiladsari
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To trace the active compound in mengkudu (morinda citrifolia) with anthelmintic acvtivity against Haemonchus contortus Murdiati, T.B; Adiwinatai, G; Hiladsari, D
Indonesian Journal of Animal and Veterinary Sciences Vol 5, No 4 (2000)
Publisher : Indonesian Animal Sciences Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (168.451 KB) | DOI: 10.14334/jitv.v5i4.191

Abstract

Intestinal parasites such Haemonchus contortus is usually controlled by management improvement and regular administration of anthelmintic. However, there is an indication of H. contortus resistance to several anthelmintic available in the market, which makes medicinal plants as an alternative anthelmintic and mengkudu or noni fruit (Morinda citrifolia) have been reported as an effective anthelmintic. To trace the active compounds responsible for anthelmintic activity against H. contortus, the mengkudu fruit was continuosly extracted into hexane, chloroform, metanol and water, followed by in-vitro study on the anthelmintic activity. The in-vitro anthelmintic activity was base on the ability of the extracts to kill the worm and the ability of the extracts to prevent egg development. The study suggested that chloroform fraction which contains alkaloid and anthraquinon have the highest anthelmintic activity and showed significant different compared to control (P≤ 0.05).   Key words: Morinda citrifolia, anthelmintic, Haemonchus contortus
To trace the active compound in mengkudu (morinda citrifolia) with anthelmintic acvtivity against Haemonchus contortus T.B Murdiati; G Adiwinatai; D Hiladsari
Jurnal Ilmu Ternak dan Veteriner Vol 5, No 4 (2000): DECEMBER 2000
Publisher : Indonesian Center for Animal Research and Development (ICARD)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (168.451 KB) | DOI: 10.14334/jitv.v5i4.191

Abstract

Intestinal parasites such Haemonchus contortus is usually controlled by management improvement and regular administration of anthelmintic. However, there is an indication of H. contortus resistance to several anthelmintic available in the market, which makes medicinal plants as an alternative anthelmintic and mengkudu or noni fruit (Morinda citrifolia) have been reported as an effective anthelmintic. To trace the active compounds responsible for anthelmintic activity against H. contortus, the mengkudu fruit was continuosly extracted into hexane, chloroform, metanol and water, followed by in-vitro study on the anthelmintic activity. The in-vitro anthelmintic activity was base on the ability of the extracts to kill the worm and the ability of the extracts to prevent egg development. The study suggested that chloroform fraction which contains alkaloid and anthraquinon have the highest anthelmintic activity and showed significant different compared to control (P≤ 0.05).   Key words: Morinda citrifolia, anthelmintic, Haemonchus contortus
Co-Authors G Adiwinatai T.B Murdiati