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All Journal Jurnal Ilmu Ternak Veteriner WARTAZOA Indonesian Bulletin of Animal and Veterinary Sciences
Eni Kusumaningtyas
Indonesian Research Center for Veterinary Science
Veterinary

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Antimicrobial, Antioxidant and Anti-inflammation Activities of Fraction and Single Peptides Derived from Mare Milk Protein Eni Kusumaningtyas; Didik Tulus Subekti; D FL Fitaningtyas
Jurnal Ilmu Ternak dan Veteriner Vol 24, No 3 (2019): SEPTEMBER 2019
Publisher : Indonesian Center for Animal Research and Development (ICARD)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14334/jitv.v24i3.1976

Abstract

Mare milk protein contains bioactive peptide which beneficial for human and animal health. Peptides in the fraction and single may show different activities.  The objectives of the study were to evaluate antimicrobial and anti-inflammation activities of the fraction and single peptide derived from mare milk protein. Antimicrobial assay was conducted by testing antibacterial and antifungal activities of fraction <3 kDa, peptide HPYFYAPELLYYANK, LVNELTEFAK and LANSLTEFAK against Escherichia coli and Candida albicans. Anti-inflammation effect was detected by interleukin 1-β (IL- 1β) and Tumor Necrosis Factor -α (TNF-α) production in mice after administration of Escherichia coli’s lipopolysaccharide (LPS) and combined with fraction or single peptide. The result showed that antibacterial and antifungal of fraction <3 kDa was higher than all of single peptide. This may because of synergistic interaction among peptide in the fraction which increase the activities. Fraction <3 kDa was also able to decrease production of IL-1β and TNF-α better than single peptide indicated its ability to decrease inflammation. Based on the results, antimicrobial and anti-inflammation activities fraction <3 kDa was better than single peptide. 
Several Functions of Rhizopus sp on Increasing Nutritional Value of Feed Ingredient Dwi Endrawati; Eni Kusumaningtyas
WARTAZOA, Indonesian Bulletin of Animal and Veterinary Sciences Vol 27, No 2 (2017): June 2017
Publisher : Indonesian Center for Animal Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (182.349 KB) | DOI: 10.14334/wartazoa.v27i2.1181

Abstract

Rhizopus sp is a type of fungi which easily grow in the soil, fruit, vegetables and fermented food. This paper describes some functions of Rhizopus sp on increasing nutritional value of feed ingredient and possibility of its application in Indonesia. Rhizopus mold has been known in Indonesia especially for tempe production for food. Research about Rhizopus sp gives knowledge for utilizing Rhizopus sp for other functions. Rhizopus sp is able to inhibit the growth of toxigenic fungus, Aspergillus flavus and to degrade aflatoxin. Rhizopus sp also produces compounds which are able to inhibit pathogenic bacteria and acts as antioxidant. Rhizopus sp absorbs some minerals and changes them to become organic minerals hence it increases mineral absorption by the body. Utilization of feed fermented by Rhizopus sp in livestock showed better result compared to non fermented feed. Rhizopus sp is also very potential to be applied as feed additive for livestock.
Co-Authors D FL Fitaningtyas Didik Tulus Subekti Dwi Endrawati