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Hubungan Indeks Masa Tubuh dan Lingkar Perut dengan Low Density Lipoprotein pada Pasien Penyakit Jantung Koroner di Poliklinik Jantung RSUP Dr. M. Djamil Padang Medika Prasetya; Fadil Oenzil; Yerizal Karani
Jurnal Kesehatan Andalas Vol 4, No 3 (2015)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v4i3.356

Abstract

Abstrak Berat badan dengan Indeks Masa Tubuh (IMT) lebih dari 30 kg/m2  pada laki-laki dan wanita akan meningkatkan risiko Penyakit Jantung Koroner (PJK) 4 kali lipat. Tingginya proporsi penyakit kardiovaskuler pada etnikMinangkabau/Padang diperkirakan berkaitan dengan tingginya prevalensi dislipidemia. Tujuan penelitian ini adalah mengetahui hubungan IMT dan Lingkar perut (LP) dengan kadar Low density Lipoprotein (LDL) pada pasien penyakit Jantung Koroner di Poliklinik Jantung RSUP Dr M Djamil Padang. Penelitian ini mengunakan rancangan analitik dengan pendekatan cross sectional study dengan mengumpulkan data primer berupa tinggi badan, berat badan, dan lingkar perut dan data sekunder berupa kadar LDL dari rekam medik pasien. Populasi studi adalah semua penderita jantung koroner dengan LDL diatas normal yang berusia 20 tahun sampai 64 tahun lebih yang berasal dari Kabupaten/Kota Propinsi Sumatera Barat  telah  berobat di Poliklinik Jantung Rumah Sakit Dr M. Djamil pada bulan Mei tahun 2012 serta bersedia berpartisipasi dalam penelitian.  LP yang tidak normal 20 orang (54,1%) yang kadar LDL tinggi. Hasil statistik diperoleh nilai p=0,02 yang berarti ada perbedaan proporsi kadar LDL tinggi antara responden LP  tidak normal  dengan kadar LDL tinggi. Dari hasil analisis diperoleh pula nilai OR = 2,64, artinya LPresponden yang tidak normal mempunyai peluang 2,64 kali untuk kadar LDL tinggi  dibandingkan responden yang LP normal. Kesimpulan penelitian ini adalah tidak ada hubungan yang signifikan IMT dengan kadar LDL. Yang menunjukan adanya hubungan adalah antara LP dengan kadar LDL tinggi.Kata kunci: IMT, LP, penyakit jantung koroner Abstract Weight gain by Body Mass Index (BMI) over 30 kg/m2 both in men and women will increase 4-fold risk of Coronary Heart Disease (CHD). The high proportion of cardiovascular disease in ethnic Minangkabau/Padangassociated to higher prevalence of dyslipidemia.  The objective of this study was to determine the relationship of BMI (body mass index) and abdominal circumference (LP) to high levels of low-density lipoproteins (LDL) in patients with CHD in the Heart Clinic Dr M Djamil Padang in May in 2012. The design of this study was a cross-sectional study tocollect primary data such as height, weight, and abdominal circumference, but LDL data got from medical records. The study population was all patients with coronary heart disease with normal LDL above 20 years old to 64 years who came from County/City of West Sumatra had been treated at the clinic Dr M. Djamil Heart Hospital in May of 2012, and are willing to participate in the study. Abnormal LP 20 people (54.1%) were high LDL levels. The statistical results obtained by  p=0.02, it can be concluded that there is a difference between the proportion of high LDL levels to highLDL levels. From the results obtained by the analysis of the value of OR = 2.64, meaning the LP respondents who do not normally have the opportunity to LDL levels of 2.64 times higher than the normal LP respondents. In this study there was no significant association with BMI levels of LDL.  that there is a relationship between the LP with high LDL. Keywords: BMI, LP, Coronary Heart Disease
TRANSPOSISI ARTERI BESAR PADA DEWASA Deni Arisanti; Rony Yuliwansyah; Akmal Edi M Hanif; Yerizal Karani; Saharman Leman
Majalah Kedokteran Andalas Vol 35, No 2 (2011): Published in August 2011
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (256.062 KB) | DOI: 10.22338/mka.v35.i2.p181-187.2011

Abstract

AbstrakSeorang laki-laki umur 50 tahun dirawat di Emergensi Penyakit Dalam RSUP Dr. M. Djamil Padang dengan keluhan utama sesak nafas meningkat sejak 1 hari yang lalu. Sesak nafas semakin meningkat jika beraktifitas, dan berkurang jika istirahat dengan posisi bantal yang ditinggikan. Jika sesak nafas sering diikuti dengan bibir dan kuku yang membiru. Pasien sudah dikenal menderita penyakit jantung bawaan, awalnya lahir dengan kulit kebiruan dan mudah tersedak jika menyusu. Dari pemeriksaan fisik didapatkan: Clubbing finger, sianosis, peningkatan Vena Jugolaris, kardiomegali, dan pitting oedema. Dari laboratorium didapatkan: Hemoglobin: 17,1 gr/dl, Hematokrit : 62%, Ureum : 39 mg/dl, Kreatinin : 2,0 mg/dl, TKK :31, Echo Cardiography: Transposisi Arteri Besar, Large Ventrikel Septal Devect, trikuspit regurgitasi dengan hipertensi pulmonal dan moderat Mitral Regurgitasi. Pasien di diagnosa dengan Congestive Heart Failure Functional Class IV LVH- RVH, irama RBBB karena transposisi Arteri Besar dengan Ventrikel Septal Defek.Kata kunci: Transposisi Arteri Besar, Kelainan Jantung Bawaan.AbstractHas been treated a 50 years old man was hospitallized in Internal emengency Department of Dr. M. Djamil Hospital Padang with cief complaints of shortness of breath influenced activity, frequent night waking due to shortness of breath, and an elevated bed with a pillow. On physical examination found: clubbing, cyanosis, increased Jugolaris veins, cardiomegaly, and pitting edema. From the laboratium: Hemoglobin: 17,1 gr/dl, Hematokrit : 62%, Ureum : 39 mg/dl, Kreatinin : 2,0 mg/dl, TKK :31, Echo Cardiography shows: Transposition of the Great Arteries, Large Ventricle Septal Defect, Tricuspid Regurgitation with pulmonary hypertension, and moderate Mitral Regurgitation. Patients with definitife diagnosis: Congestive Heart Failure Functional Class IV LVH- RVH, RBBB rhythm Cause By Transposition of the Great Arteries with a Ventrikel Septal Defec.Key word : Transposition of the Great Arteries, Kongenital Heart Desease.
HDL DAN ATEROSKLEROSIS Erizon Erizon; Yerizal Karani
HUMAN CARE JOURNAL Vol 5, No 4 (2020): Human Care Journal
Publisher : Universitas Fort De Kock

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32883/hcj.v5i4.851

Abstract

Atherosclerosis is a change that occurs in the arterial wall, which is characterized by the accumulation of extracellular lipids, recruitment and accumulation of leukocytes, foam cell formation, migration and proliferation of myocytes, extracellular matrix deposits (e.g. collagen, calcium), caused by a variety of pathogenesis that is chronic progressive, focal or diffuse and has acute or chronic manifestations that cause thickening and stiffness in arteries. Cardiovascular disease caused by atherosclerosis and thrombosis is a major cause of premature death and causes years of limitations in European countries and is also increasing in developing countries. Among many other independent risk factors for coronary heart disease (CHD) determined based on epidemiological studies, low HDL-C levels are one of the strongest. Based on the results obtained from the literature, HDL is an anti-atherogenic lipoprotein. HDL plays a role in preventing the process of atherosclerosis not only through the pathway of cholesterol transport but also through anti-inflammatory and antioxidant effects in the walls of blood vessels. This literature review focus on how is the role of HDL protection against atherosclerotic processes in the body