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Rizaldy Taslim Pinzon
Fakultas Kedokteran Universitas Kristen Duta Wacana
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Nursing Public Health

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Hubungan Diabetes Melitus dengan Gangguan Fungsi Kognitif Post Stroke Iskemik di Rumah Sakit Bethesda Satrianti Totting; Rizaldy Taslim Pinzon; Bowo Widiasmoko
Jurnal Kesehatan Andalas Vol 6, No 3 (2017)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v6i3.752

Abstract

Ada setengah pasien post stroke mengalami gangguan fungsi kognitif. Diabetes mellitus merupakan salah satu factor risiko stroke sekaligus factor risiko terjadinya gangguan fungsi kognitif. Tujuan penelitian adalah mengukur pengaruh diabetes mellitus terhadap gangguan fungsi kognitif post stroke iskemik. Penelitian ini menggunakan metode cross sectional. Data diambil dengan melakukan pengukuran fungsi kognitif pasien post stroke iskemik menggunakan instrument MoCA-INA dan CDT, data sekunder diambil dari Stroke Registry di RumahSakit Bethesda Yogyakarta pada tahun 2010-2017. Data dianalisis dengan chi-square test untuk analisis bivariat, serta regresi logistic untuk analisis multivariat. Dari 110 subjek penelitian terdapat pasien dengan gangguan fungsi kognitif (MoCA-INA < 26 dan CDT > 1) sebanyak 75 (68.2%) pasien, dan fungsi kognitif baik (MoCA-INA >= 26 dan CDT = 1) sebanyak 35 (31.8%) pasien. Analisis bivariat menunjukkan bahwa diabetes mellitus tidak berhubungan dengan gangguan fungsi kognitif post stroke iskemik (OR: 1.506, 95% CI: 0.654-3.466, p: 0.334). Analisis multivariate dengan regresi logistik didapatkan usia, onset, serangan stroke berulang, lesi temporal dan parietal sebagai faktor yang paling berpengaruh terhadap terjadinya gangguan fungsi kognitif post stroke iskemik. Simpulan penelitian ini adalah diabetes mellitus tidak mempengaruhi terjadinya gangguan fungsi kognitif post stroke iskemik.
Efek kombinasi vitamin B1, B6, B12 untuk menurunkan intensitas nyeri pada penderita neuropatik diabetes Rizaldy Taslim Pinzon; Jesisca Jesisca
Jurnal Gizi Klinik Indonesia Vol 14, No 4 (2018): April
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3500.258 KB) | DOI: 10.22146/ijcn.26975

Abstract

Background: Neuropathy diabetic pain are common symptom in patient with diabetic melitus. The combination of vitamin B1, vitamin B6, and vitamin B12 usually used for treatment the pain, the result of previous studies are limited and conflicting.Objective: The aim of the study to measure the convering of intensity of pain in diabetic neuropathy.Method: The method of study using quase experimental design with pre and post treatment patient were selected by conservative sampling method from Bethesda Hospital, Yogyakarta. There are 68 patient diabetic neuropathy to follow in the study. Fact patient received combination of vitamin B1 100 mg, vitamin B6 100 mg, and vitamin B12 5000 mcg once a day for 3 month. Pain intensity measured using visual analog scale (VAS) on the first initial visited after 30th day and 90th day.Results: The 68 patient consist of 27 (39.7%) male and 41 (60.3%) women. The mean age 58.32±6.72 years. The mean duration of Diabetic 4.32±2.86 year. The study showed that the pain intensity lower significantly after received vitamin B (p<0.001). The mean pain intensity in first VAS 43.68±12.32 lower to 20.42±11.24 and in the end of study lower to 12.23±8.39.Conclusion: The combination of vitamin B1, B6, B12 significantly lower pain intensity of patient diabetic neuropathy.
Co-Authors Bowo Widiasmoko Jesisca Jesisca Satrianti Totting