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Perbedaan Kadar Natrium pada Packed Red Cell Berdasarkan Lama Penyimpanan di Bank Darah RSUP Dr. M. Djamil Padang Hesty Rhauda Ashan
Jurnal Kesehatan Andalas Vol 9, No 1 (2020): Online March 2020
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v9i1.1237

Abstract

Packed Red Cell (PRC) adalah komponen darah yang didapat setelah sebagian besar plasma dipisahkan dari Whole Blood (WB) dan memiliki nilai hematokrit sekitar 80%. Packed red cell disimpan pada suhu 2-6°C selama 21–42 hari tergantung larutan antikoagulan-pengawet yang digunakan. Pompa Na+/K+ATPase menjadi inaktif pada suhu 4°C menyebabkan natrium masuk ke dalam sel dan kalium keluar dari sel. Proses ini terjadi perlahan dan terus menerus sehingga kadar natrium pada plasma PRC menurun sesuai dengan bertambahnya waktu penyimpanan. Tujuan: Menentukan perbedaan kadar natrium PRC antara penyimpanan ≤14 hari dan >14 hari di bank darah RSUP Dr.M.Djamil Padang. Metode: Penelitian ini adalah suatu penelitian analitik dengan rancangan potong lintang, dimulai dari bulan September 2016 sampai Oktober 2018. Kadar natrium diperiksa dengan electrolyte analyzer. Analisis data menggunakan uji-t, bermakna bila p<0,05. Hasil: Rerata kadar natrium pada penyimpanan ≤14 hari adalah 150,5 (2,9)  mmoL/L dan 143,3 (4,3) mmoL/L pada penyimpanan >14 hari. Terdapat perbedaan bermakna rerata kadar natrium PRC berdasarkan lama penyimpanan (p= 0,0001). Simpulan: Terdapat perbedaan kadar natrium PRC pada lama penyimpanan ≤14 hari dan >14 hari.Kata kunci: lama penyimpanan, jejas penyimpanan, natrium, packed red cell
ASPERGILLUS SP. PADA ULKUS KORNEA Hesty Rhauda Ashan; Ellyza Nasrul; Abdul Aziz Djamal
HUMAN CARE JOURNAL Vol 5, No 2 (2020): Human Care Journal Special Edition
Publisher : Universitas Fort De Kock

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32883/hcj.v5i2.737

Abstract

Aspergillosis is a disease caused by Aspergillus sp., especially Aspergillus fumigatus which induce granulomatosis inflammation in mucous membranes, eyes, bronchi, ears. Aspergillus sp. microscopically characterized as septate and branched hyphae. Fungal corneal ulcers are more common in tropical climates. Aspergillus sp. is the most common fungi causes corneal ulcer. Risk factors include the use of antibiotics, long-term corticosteroids, trauma, contact lenses, and corneal surgery. 50-year-old female with main complaint: increased redness and pain of the right eye after trauma from twig. Palpebral edema, conjunctival injection, ciliary injection, corneal ulcers, maceration, and impending were found from physical examination of the right eye. Fungal culture on sabouraud dextrose agar (SDA) culture media found growth of fungi Aspergillus sp. which macroscopically has fertile hyphae on the surface and vegetative hyphae below the surface, and microscopically characterized as septate and branching hyphae. Corneal ulcers in the tropics are mostly caused by fungi. Aspergillus sp. and Fusarium sp. is most commonly found in tropical climates, while Candida is more commonly found in cold climates. Diagnosis of corneal ulcer ec Aspergillus sp. is obtained based on history, clinical manifestation and found Aspergillus sp. from fungal culture.