Ibnu Pranoto Ibnu Pranoto
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Prophylactic uterotonic agent to avoid postpartum bleeding on normal vaginal delivery Ibnu Pranoto, Ibnu Pranoto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 33, No 04 (2001)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (132.035 KB)

Abstract

Objective: To compare the volume of blood loss after normal vaginal delivery that have been given prophylactic uterotonic agents, 2.5 IU oxytocin, 5 IU oxytocin, 2.5 IU oxytocin plus 0.2 mg ergometrin, and 5 IU oxytocin plus 0.2 mg ergometrin.Methods: A Randomized control trial study was performed, 22 normal vaginal deliveries were given 2.5 IU oxytocin. 5 IU oxytocin was for 26 normal deliveries, 2.5 IU oxytocin plus 0.2 mg ergometrin for 29 deliveries and 5 lU oxytocin plus 0.2 mg ergometrin for 27 deliveries. The agents were administered intramuscularly or intravenously at a time of crowning. One way-anova test was used in this study. Intrapartum mothers with the normal vaginal delivery in Obstetrics and Gyneclogy Department of Sardjito General Hospital, Yogyakarta and Soeradji General Hospital, Klaten, between April 1t and July 28th 1988. Results: There is no significant difference between the second stage blood loss in the deliveries given 2.5 IU and 5 IU oxytocin with or without ergometrin. On the other hand, administration of 2.5 IU oxytocin has been statistically significant to reduce the mean blood loss on the third stage of labor compared to the other regiments. Prophylactic 2.5 IU and 5 IU oxytocin with or without ergometrin did not show any significant difference on the fourth stage of labor. The mean of blood loss after normal vaginal delivery was statisticaly significantly reduced by giving 2.5 IU oxytocin as the prophylactic agent compared to the other treatments in this study.Conclusion: The administering of 2.5 IU oxytocin was more significant in preventing postpartum bleeding in the third stage of labor and the postpartum bleeding. Ergometrin addition to oxytocin was not proved to decrease the blood loss in any stage of labor and portpartum bleeding as well.Keywords : Prophylactic uterotonic agents - oxytocin - ergometrin - normal vaginal delivery - postpartum bleeding.
Klinefelter syndrome Ibnu Pranoto, Ibnu Pranoto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 23, No 03 (1991)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (352.657 KB)

Abstract

A 10-year old boy presented small testicles, a small penis, hypospadia, scanty hair growth, and long legs and arms indicating Klinefelter syndrome. Klinefelter syndrome is one of the abnormality of excessive number of sex chromosomes in which the male phenotype presents female characteristics such as breast development, scanty hair growth, long arms and legs, small testes and high pitch voice.The examination in the above case reveals two X-chromosomes and one Y-chrtimosome in the nuclei of cells as the result of fertilization from XX ovum and Y spermatozoa or from X ovum with XY spermatozoa!. Research studies showed there were 70% XXYmale cases in which their XX chromosomes came from the mother, whereas the other 30% cases their XYchromosomes came from the father. Other studies showed the poSsible relationship of Klinefelter syndrome with the incidence of leukemia.The result of chrothosomal analysysindicates that the abOve case was trUIYKlinefelter syndrome.Key Words: Klinefelter syndrome - genital abnormality - XY chromosomes - genetic mapping - clinical generics
The Evaluation of Vaginal Hysterectomy Using Spinal Anaesthesia Ibnu Pranoto, Ibnu Pranoto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 39, No 02 (2007)
Publisher : Universitas Gadjah Mada

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Abstract

Background. Vaginal hysterectomy can be performed on patient under general or spinal anesthesia. There are some advantages of spinal anesthesia compared to general anesthesia, although some prefer general anesthesia. We have done frequently vaginal hysterectomy using spinal anesthesia and we are reporting our experience.Objective:To know the spinal anethesia efficency compared to general anesthesia in terms of duration of vaginal hysterectomy operation, amount of bleeding and length of stay.Design: Cross sectional descriptive studySetting: Sardjito HospitalMaterials and methods: Patients underwent vaginal hysterectomy in Dr. Sardjito Hospital from March 2005 until February 2007Results: 50 patients underwent vaginal hysterectomy that consisted of 44 patients with spinal anesthesia and 6 patients with general anesthesia. Vaginal hysterectomy with spinal anesthesia had shorter duration of operation (1.93 hours) compared to general anesthesia (1.95 hours). Patients length of stay was shorter with spinal anesthesia (5.8 days) compared to general anesthesia (9 days). The average amount of blood loss in spinal anesthesia was (250.34 mil compared to general anesthesia (625.0 mil.Conclusion: This study suggests that spinal anesthesia reduces length of hospital stay and amount of blood loss in patients with vaginal hysterectomy compared to general anesthesiaKey Words: vaginal hysterectomy, spinal anesthesia, general anesthesia, duration of operation, amount of bleeding and length of stay.
The role of amniocentesis in genetic anomaly detection Ibnu Pranoto, Ibnu Pranoto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 23, No 02 (1991)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (277.865 KB)

Abstract

Since the beginning of the Landsteiner era, genetics has been developing tremendously. Genetics now is used in genetic counselling, genetic screening and in the management of genetic disorders or diseases due to the fast technological development during the last two decades.Amniocentesis, one of the products of this technological development, is indeed valuable, as it can detect any chromosomal abnormality of the fetus in utero, thus genetic defects among babies, can be prevented.By taking 10-20 ml of amniotic fluid during 14-16 weeks of gestation by amniocen tesis, disposed fetal cells in the fluid can be immediately cultured. After 2-3 weeks, chromosomal analysis can be undertaken to make its karyotype. Other than the above benefit, amniocentesis can also be used for detection of any biochemical abnormality of the fetus, thus early prevention of biochemical disorders among babies can be done.With the application of amniocentesis as one of the diagnostic tools which continuously improves, its benefits help human beings in the prevention of birth defects and in counselling couples who are expecting healthy babies in their marriage.To extend the beneficial aspect of amniocentesis to grass-root level, improvement of knowledge and skills of amniocentesis of practicians is mandatory.Key Words: amniocentesis - amniotic cell culture - chromosomal analysis - genetic counselling -prevention of birth defects
Laparoscopic Assessment of Pelvic Inflammatory Diseases Among IUD Users Ibnu Pranoto, Ibnu Pranoto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 24, No 03 (1992)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (539.861 KB)

Abstract

Penyakit Radang Panggul (PRP) adalah salah satu komplikasi terpenting yang terjadi pada pemakaian IUD. Telah diteliti 390 talon akseptor sterilisasi ligasi tuba secara laparoskopi, dengan perincian 194 kasus (49,7%) akseptor IUD dan 196 (50,3%) bukan akseptor IUD; dilakukan eksplorasi rongga panggul untuk melihat adanya PRP sebelum dilakukan sterilisasi ligasi tuba. Didapat angka risiko relatif 95% PRD pada aksep for IUD sebany-ak 2,52 dibandingdengan non-IUD. Makin lama pemakaian IUD, makin besar risiko terjadinya PRP clan kenaikan yang tajam PRP se telah pemakaian 2 tahun. hisersi IUD oleh bidan atau dokter umum mempunyai risiko hampir sama untuk terjadinya PRP. Bila insersi dilakukan dengan tempat dan peralatan medis yang kurang baik, maka risiko kejadian PRP lebih besar.Disimpulkan bahwa laparoskopi eksplorasi memberikan keuntungan yang lebih dalam mendiagnosis PRP, terutama yang secara klinis ridak dapat ditentukan.Key Words: pelvic inflammatory disease - laparoscopic sterilization - IUD - family planning program - gynaecology
The Evaluation of Vaginal Hysterectomy Using Spinal Anaesthesia Ibnu Pranoto Ibnu Pranoto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 39, No 02 (2007)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background. Vaginal hysterectomy can be performed on patient under general or spinal anesthesia. There are some advantages of spinal anesthesia compared to general anesthesia, although some prefer general anesthesia. We have done frequently vaginal hysterectomy using spinal anesthesia and we are reporting our experience.Objective:To know the spinal anethesia efficency compared to general anesthesia in terms of duration of vaginal hysterectomy operation, amount of bleeding and length of stay.Design: Cross sectional descriptive studySetting: Sardjito HospitalMaterials and methods: Patients underwent vaginal hysterectomy in Dr. Sardjito Hospital from March 2005 until February 2007Results: 50 patients underwent vaginal hysterectomy that consisted of 44 patients with spinal anesthesia and 6 patients with general anesthesia. Vaginal hysterectomy with spinal anesthesia had shorter duration of operation (1.93 hours) compared to general anesthesia (1.95 hours). Patients length of stay was shorter with spinal anesthesia (5.8 days) compared to general anesthesia (9 days). The average amount of blood loss in spinal anesthesia was (250.34 mil compared to general anesthesia (625.0 mil.Conclusion: This study suggests that spinal anesthesia reduces length of hospital stay and amount of blood loss in patients with vaginal hysterectomy compared to general anesthesiaKey Words: vaginal hysterectomy, spinal anesthesia, general anesthesia, duration of operation, amount of bleeding and length of stay.
Prophylactic uterotonic agent to avoid postpartum bleeding on normal vaginal delivery Ibnu Pranoto Ibnu Pranoto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 33, No 04 (2001)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (132.035 KB)

Abstract

Objective: To compare the volume of blood loss after normal vaginal delivery that have been given prophylactic uterotonic agents, 2.5 IU oxytocin, 5 IU oxytocin, 2.5 IU oxytocin plus 0.2 mg ergometrin, and 5 IU oxytocin plus 0.2 mg ergometrin.Methods: A Randomized control trial study was performed, 22 normal vaginal deliveries were given 2.5 IU oxytocin. 5 IU oxytocin was for 26 normal deliveries, 2.5 IU oxytocin plus 0.2 mg ergometrin for 29 deliveries and 5 lU oxytocin plus 0.2 mg ergometrin for 27 deliveries. The agents were administered intramuscularly or intravenously at a time of crowning. One way-anova test was used in this study. Intrapartum mothers with the normal vaginal delivery in Obstetrics and Gyneclogy Department of Sardjito General Hospital, Yogyakarta and Soeradji General Hospital, Klaten, between April 1't and July 28th 1988. Results: There is no significant difference between the second stage blood loss in the deliveries given 2.5 IU and 5 IU oxytocin with or without ergometrin. On the other hand, administration of 2.5 IU oxytocin has been statistically significant to reduce the mean blood loss on the third stage of labor compared to the other regiments. Prophylactic 2.5 IU and 5 IU oxytocin with or without ergometrin did not show any significant difference on the fourth stage of labor. The mean of blood loss after normal vaginal delivery was statisticaly significantly reduced by giving 2.5 IU oxytocin as the prophylactic agent compared to the other treatments in this study.Conclusion: The administering of 2.5 IU oxytocin was more significant in preventing postpartum bleeding in the third stage of labor and the postpartum bleeding. Ergometrin addition to oxytocin was not proved to decrease the blood loss in any stage of labor and portpartum bleeding as well.Keywords : Prophylactic uterotonic agents - oxytocin - ergometrin - normal vaginal delivery - postpartum bleeding.
Laparoscopic Assessment of Pelvic Inflammatory Diseases Among IUD Users Ibnu Pranoto Ibnu Pranoto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 24, No 03 (1992)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (539.861 KB)

Abstract

Penyakit Radang Panggul (PRP) adalah salah satu komplikasi terpenting yang terjadi pada pemakaian IUD. Telah diteliti 390 talon akseptor sterilisasi ligasi tuba secara laparoskopi, dengan perincian 194 kasus (49,7%) akseptor IUD dan 196 (50,3%) bukan akseptor IUD; dilakukan eksplorasi rongga panggul untuk melihat adanya PRP sebelum dilakukan sterilisasi ligasi tuba. Didapat angka risiko relatif 95% PRD pada aksep for IUD sebany-ak 2,52 dibandingdengan non-IUD. Makin lama pemakaian IUD, makin besar risiko terjadinya PRP clan kenaikan yang tajam PRP se telah pemakaian 2 tahun. hisersi IUD oleh bidan atau dokter umum mempunyai risiko hampir sama untuk terjadinya PRP. Bila insersi dilakukan dengan tempat dan peralatan medis yang kurang baik, maka risiko kejadian PRP lebih besar.Disimpulkan bahwa laparoskopi eksplorasi memberikan keuntungan yang lebih dalam mendiagnosis PRP, terutama yang secara klinis ridak dapat ditentukan.Key Words: pelvic inflammatory disease - laparoscopic sterilization - IUD - family planning program - gynaecology
Klinefelter syndrome Ibnu Pranoto Ibnu Pranoto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 23, No 03 (1991)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (352.657 KB)

Abstract

A 10-year old boy presented small testicles, a small penis, hypospadia, scanty hair growth, and long legs and arms indicating Klinefelter syndrome. Klinefelter syndrome is one of the abnormality of excessive number of sex chromosomes in which the male phenotype presents female characteristics such as breast development, scanty hair growth, long arms and legs, small testes and high pitch voice.The examination in the above case reveals two X-chromosomes and one Y-chrtimosome in the nuclei of cells as the result of fertilization from XX ovum and Y spermatozoa or from X ovum with XY spermatozoa!. Research studies showed there were 70% XXYmale cases in which their XX chromosomes came from the mother, whereas the other 30% cases their XYchromosomes came from the father. Other studies showed the poSsible relationship of Klinefelter syndrome with the incidence of leukemia.The result of chrothosomal analysysindicates that the abOve case was trUIYKlinefelter syndrome.Key Words: Klinefelter syndrome - genital abnormality - XY chromosomes - genetic mapping - clinical generics
The role of amniocentesis in genetic anomaly detection Ibnu Pranoto Ibnu Pranoto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 23, No 02 (1991)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (277.865 KB)

Abstract

Since the beginning of the Landsteiner era, genetics has been developing tremendously. Genetics now is used in genetic counselling, genetic screening and in the management of genetic disorders or diseases due to the fast technological development during the last two decades.Amniocentesis, one of the products of this technological development, is indeed valuable, as it can detect any chromosomal abnormality of the fetus in utero, thus genetic defects among babies, can be prevented.By taking 10-20 ml of amniotic fluid during 14-16 weeks of gestation by amniocen tesis, disposed fetal cells in the fluid can be immediately cultured. After 2-3 weeks, chromosomal analysis can be undertaken to make its karyotype. Other than the above benefit, amniocentesis can also be used for detection of any biochemical abnormality of the fetus, thus early prevention of biochemical disorders among babies can be done.With the application of amniocentesis as one of the diagnostic tools which continuously improves, its benefits help human beings in the prevention of birth defects and in counselling couples who are expecting healthy babies in their marriage.To extend the beneficial aspect of amniocentesis to grass-root level, improvement of knowledge and skills of amniocentesis of practicians is mandatory.Key Words: amniocentesis - amniotic cell culture - chromosomal analysis - genetic counselling -prevention of birth defects