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All Journal Majalah Kedokteran Gigi Indonesia MDJ (Makassar Dental Journal)
Netta Anggraini
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Dentistry

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Differences in results of infrabony pocket treatment with addition of platelet rich fibrin and platelet rich plasma gel in DFDBA bone graft Netta Anggraini; Sri Pramestri Lastianny; Al Sri Koes Soesilowati
Majalah Kedokteran Gigi Indonesia Vol 5, No 1 (2019): April
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (390.791 KB) | DOI: 10.22146/majkedgiind.37423

Abstract

Treatment of infrabony pocket makes use of bone graft material demineralized freeze dried bone allograft (DFDBA) from different individuals which has undergone demineralization process and it is osteoinductive. Enhancement of growth factor was done by adding platelet rich fibrin (PRF) and platelet rich plasma (PRP). PRP is activated with an addition of calcium chloride CaCl2) to form gel. The method used to apply the bone grafting material is open flap debridement OFD). This research aimed to reveal the differences in the results of infrabony pocket treatment using PRF and PRP gel with an addition of DFDBA. The sample was taken from 20 infrabony pocket points divided into 2 groups, 10 infrabony pocket were treated with OFD+DFDBA+PRF and the other were treated with OFD+DFDBA+PRP gel. Pocket depth (PD) was measured on the baseline and the first and third month after treatment. Alveolar bone height was measured using cone beam computed tomography (CBCT) radiograph on the baseline to the third month after treatment. The results of this research showed that there was difference in the results of infrabony pocket treatment using PRF and PRP gel with an addition of DFDBA which could be observed from a reduction in PD from the baseline, month 1 and month 3 as well as reduction in alveolar bone height from the baseline to month 3. This research concluded that infrabony pocket treatment PRF application yields better results than PRP gel application in terms of PD and alveolar bone height reduction.
Effectiveness of Alue vera (Aloe barbadensis Miller) extract on the growth of Porphyromonas gingivalis: Efektivitas ekstrak Aloe vera (Aloe barbadensis Miller) terhadap pertumbuhan Porphyromonas gingivalis Netta Anggraini; Syakira Awlia Syah; Wulan Anggestia
Makassar Dental Journal Vol. 14 No. 3 (2025): Volume 14 Issue 3 December 2025
Publisher : Makassar Dental Journal PDGI Makassar

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Abstract

Penggunaan antibiotik dalam pengobatan periodontitis sering menyebabkan resistensi, sehingga diperlukan bahan alternatif dari alam. Aloe vera (Aloe barbadensis Miller) mengandung senyawa aktif seperti saponin, flavonoid, tanin, dan antrakuinon yang memiliki sifat antibakteri. Penelitian ini menguji efektivitas ekstrak aloe vera terhadap pertumbuhan Porphyromonas gingivalis dengan mengukur zona inhibisi, konsentrasi hambat minimum (KHM), dan konsentrasi bakterisida minimum (KBM). Penelitian eksperimen laboratorium ini menggunakan metode difusi cakram untuk menguji zona inhibisi, dan metode pengenceran untuk menentukan KHM dan KBM dengan konsentrasi ekstrak adalah 3,12%, 6,25%, 12,50%, 25%, 50%, dan 100%, dengan kontrol positif metronidazole dan kontrol negatif etanol 96%. Ekstrak aloe vera efektif menghambat pertumbuhan P.gingivalis. Diameter zona hambatan terbesar ditemukan pada konsentrasi 100% (27,16 mm), sedangkan konsentrasi terendah 3,12% (8,8 mm). Nilai KHM ditemukan pada konsentrasi 3,12%, dan nilai pada konsentrasi 12,50%. Semakin tinggi konsentrasi ekstrak aloevera, semakin besar daya penghambatan, bahkan pada konsentrasi 50% dan 100%, efektivitasnya lebih tinggi daripada metronidazole. Disimpulkan bahwa ekstrak aloe vera memiliki potensi sebagai agen antibakteri alami terhadap P.gingivalis dan dapat menjadi alternatif dalam pengobatan penyakit periodontal.
Co-Authors Al Sri Koes Soesilowati Sri Pramestri Lastianny, Sri Pramestri Syakira Awlia Syah Wulan Anggestia