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All Journal Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) ODONTO Dental Journal Odonto dental journal
Rinaldi Budi Utomo
Universitas Gadjah Mada
Health Professions Medicine & Pharmacology

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PENGARUH KONSENTRASI GEL THEOBROMINE TERHADAP KETAHANAN KEKERASAN PERMUKAAN EMAIL GIGI DESIDUI indah lestari vidyahayati; Rinaldi Budi Utomo; Indah Titien Soeprihati
ODONTO : Dental Journal Vol 6, No 1 (2019): July 2019
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.6.0.8-13

Abstract

Background: Primary tooth enamel are susceptible to damage because it has a low thickness so it requires preventing treatments to maintain. Theobromine, an alkaloid of the methylxanthine group, has been shown to improve crystallinity and resistance of enamel apatite solubility to acids. The enamel resistance to acid requires a series of test of physical properties, by measuring at microhardness. This study analyzes the effect of theobromine gel consentration on the hardness resistance of primary incisors enamel surfaces.Method: Twenty-fve specimens were divided into 5 groups of topical application of theobromine gel with concentrations of 1%, 2%, 3%, 4%, and 5%, and then immersed in acidic solution. Results were analyzed using one-way ANOVAResult: One-way ANOVA test showed signifcant differences in the increase and decrease in enamel microhardness after the application of theobromine gel and acid immersion (p <0.05). The highest values of increase and decrease in enamel microhardness (764,74±187,08 VHN and 457,18±54,37 VHN, respectively) was shown in 5% group of theobromine gel.Conclusion: The higher theobromine gel concentration, the higher the microhardness value but unable to maintain the enamel resistance against acid. The 5% theobromine gel concentration was the most effective one to increase the microhardness of primary teeth enamel.
PENGARUH KONSENTRASI GEL THEOBROMINE TERHADAP KETAHANAN KEKERASAN PERMUKAAN EMAIL GIGI DESIDUI indah lestari vidyahayati; Rinaldi Budi Utomo; Indah Titien Soeprihati
Odonto : Dental Journal Vol 6, No 1 (2019): July 2019
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (395.718 KB) | DOI: 10.30659/odj.6.0.8-13

Abstract

Background: Primary tooth enamel are susceptible to damage because it has a low thickness so it requires preventing treatments to maintain. Theobromine, an alkaloid of the methylxanthine group, has been shown to improve crystallinity and resistance of enamel apatite solubility to acids. The enamel resistance to acid requires a series of test of physical properties, by measuring at microhardness. This study analyzes the effect of theobromine gel consentration on the hardness resistance of primary incisors enamel surfaces.Method: Twenty-fve specimens were divided into 5 groups of topical application of theobromine gel with concentrations of 1%, 2%, 3%, 4%, and 5%, and then immersed in acidic solution. Results were analyzed using one-way ANOVAResult: One-way ANOVA test showed signifcant differences in the increase and decrease in enamel microhardness after the application of theobromine gel and acid immersion (p <0.05). The highest values of increase and decrease in enamel microhardness (764,74±187,08 VHN and 457,18±54,37 VHN, respectively) was shown in 5% group of theobromine gel.Conclusion: The higher theobromine gel concentration, the higher the microhardness value but unable to maintain the enamel resistance against acid. The 5% theobromine gel concentration was the most effective one to increase the microhardness of primary teeth enamel.
Pengaruh Garam Krayan terhadap Bakteri Cairan Sulkus Gingiva Anak dengan Gingivitis Ringan (Kajian pada Streptococcus alpha) Caecilia Dewi Ratna Prathiwi; Rinaldi Budi Utomo; Putri Kusuma Wardhani
Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Vol 10, No 1 (2023): February
Publisher : Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jfst.v10i1.4566

Abstract

Latar belakang: gingivitis adalah Penyakit periodontal paling sering terjadi pada anak-anak. Streptococcus alpha (S. alpha) adalah bakteri yang paling sering ditemukan pada gingivitis anak. Pertumbuhan bakteri patogen dalam rongga mulut dapat dicegah dengan Antibakteri. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh larutan garam Krayan pada bakteri yang ditemukan pada cairan sulkus gingiva terutama S.alpha.Metode: penelitian ini adalah ekperimental laboratorium. Streptococcus alpha diperoleh dari isolasi dari cairan sulkus gingiva anak dengan gingivitis ringan. Garam Krayan diperoleh dari pegunungan Krayan di Kalimantan Utara. Konsentrasi larutan yang digunakan adalah 20%, 25%, 30%, 35% dan 40%. Hambatan pertumbuhan garam Krayan terhadap S. alpha dihitung dengan menggunakan zona hambatan pada agar Mueller Hinton yang ditambahkan agar darah domba. Uji statistik penelitian ini menggunakan uji One Way Anova.Hasil: hasil penelitian menunjukkan bahwa larutan garam Krayan 20% memiliki diameter zona hambat 12.380 ± .22550mm, konsentrasi 25% 13,568 ± .11122, konsentrasi 30% 14,578 ± .12337, konsentrasi 35% 19,400 ± .12550 dan konsentrasi 40% 21,130 ± .04743mm. Hasil uji statistik menunjukkan adanya perbedaan yang signifikan di seluruh kelompok perlakuan.Kesimpulan: garam Krayan memiliki pengaruh daya hambat terhadap pertumbuhan S. alpha. Semakin besar konsentrasi larutan garam semakin besar pula hambatan yang dihasilkan.
Co-Authors Caecilia Dewi Ratna Prathiwi indah lestari vidyahayati Indah Titien Soeprihati Putri Kusuma Wardhani