Economic progress, environmental improvement, and the advancement of science, mainly due to the advancesof medical science, were able to reduce infant mortality. This study aimed to analyze the effect of GDP per capita,mother’s level of education and health care proxy with the medical delivery against infant mortality. The data usedin this study is secondary data for 23 years were obtained from various sources such as CPM and the Bali ProvincialHealth Department. The analysis technique used is multiple linear regression analysis techniques. Based on theanalysis it was found that the variable GDP per capita has negative effect but not significant on infant mortality.Variable levels of maternal education and health care variables are proxied by the medical delivery and significantnegative effect on infant mortality. This means that the higher the mother’s education and medical delivery theinfant mortality rate will decrease. GDP per capita have a negative effect but not significant effect on infant mortality,however, the government is expected to continue to develop programs to revitalize the economy. Mother’s educationand medical delivery and significant negative effect therefore the government is expected to provide scholarships forpoor women and expanding medical delivery in all regions of the province of Bali. The government is also expectedto continue to be consistent in the development program of clean water and drinking water quality, provision ofvitamins, infant immunization, and provide socialization clean and healthy lifestyle behaviors to reduce infantmortality and achievement of the MDGs in Bali Province.