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Baiq Renny Kamaliani
Praktisi Dokter Hewan di Kota Mataram Lombok, Nusa Tenggara Barat
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Public Health Veterinary

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Gambaran Histopatologi Ginjal Tikus Wistar Diabetes Melitus Eksperimental yang Diberikan Ekstrak Etanol Daun Kelor Baiq Renny Kamaliani; Ni Luh Eka Setiasih; Ida Bagus Oka Winaya
Buletin Veteriner Udayana Vol. 11 No. 1 Pebruari 2019
Publisher : The Faculty of Veterinary Medicine, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (199.19 KB) | DOI: 10.24843/bulvet.2019.v11.i01.p12

Abstract

This study aims to prove that the Moringa leaf extract can improve renal histological structure of diabetic Wistar rats. Wistar rats were divided into six groups, so that each group has four replications. K1 as the positive control was not given the extract, K2 was administered the extract dose 100 mg/kg, K3 was administered the extract dose 200 mg/kg, K4 was administered the extract dose 300 mg/kg, K5 was administered the extract dose 400 mg/kg, K6 was administered the extract dose 500 mg/kg. The administrations of extract were held for five weeks. Rats then sacrificed and the kidneys were taken for the histopathology preparations with Hematoxylin-Eosin staining (HE). The observations indicate fatty degeneration and necrosis of the kidneys. Kruskal Wallis test results of all treatments showed p = 0.001 in both fatty degeneration and necrosis (p <0.05).
Co-Authors Ida Bagus Oka Winaya Ni Luh Eka Setiasih