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All Journal E-Jurnal Medika Udayana Bioscientia Medicina : Journal of Biomedicine and Translational Research Bioscientia Medicina : Journal of Biomedicine and Translational Research
Ida Bagus Aditya Mayanda
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience

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TINGKAT PENGETAHUAN MENCUCI TANGANPENUNGGU PASIEN RUANG TERAPI INTENSIF INSTALASI ANESTESIOLOGI DAN TERAPI INTENSIF RUMAH SAKIT UMUM PUSAT SANGLAH DENPASAR Ida Bagus Aditya Mayanda; I Gusti Agung Gede Utara Hartawan
E-Jurnal Medika Udayana Vol 10 No 9 (2021): Vol 10 No 09(2021): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2021.V10.i9.P09

Abstract

Menjaga kebersihan tangan sangatlah penting dikalangan praktisi kesehatan karena dapat mencegah penularan infeksi nosokomial pada pasien lain maupun penunggu pasien. Perilaku cuci tangan yang benar di pulau Bali menurut data Riskesdas pada tahun 2013, sebesar 66,7% masyarakat pulau Bali sudah mencuci tangan dengan benar. Menjaga kebersihan tangan dengan mencuci tangan pakai sabun dapat mencegah beberapa penyakit yang sering terjadi dimasyarakat. Rancangan penelitian yang digunakan adalah deskriptif dengan pendekatan cross-sectional study. Pengambilan sampel menggunakan teknik consecutive sampling. Tempat penelitian ini dilakukan di ruang tunggu Ruang Terapi Intensif (RTI) RSUP Sanglah Denpasar. Subjek penelitian adalah seluruh penunggu pasien yang dirawat di RTI RSUP Sanglah Denpasar periode April – September 2016. Pada penelitian ini didapatkan 102 orang responden bersedia menjadi sampel yang memenuhi kriteria inklusi dan eksklusi. Dari 102 responden didapatkan: katagori rendah sebanyak 41,2% (n=42), katagori sedang sebanyak 22,5% (n=23), katagori tinggi sebanyak 36,3% (n=37). Responden dengan tingkat pendidikan sarjana memiliki persentase tertinggi mendapatkan tingkat pengetahuan tinggi (57,1%), Sedangkan responden dengan tingkat pendidikan SMA memiliki persentase tertinggi mendapat tingkat pengetahuan rendah (48,0%). Responden dengan kelompok umur 20-30 tahun memiliki persentase tertinggi mendapatkan tingkat pengetahuan tinggi (48,5%), sedangkan responden dengan kelompok umur 41-50 tahun memiliki persentase tertinggi mendapat tingkat pengetahuan rendah (48,1%). Penelitian ini dapat dilanjutkan dengan mempertimbangkan pekerjaan, jenis kelamin, sikap dan perilaku terhadap kebiasaan mencuci tangan. Kata kunci: tingkat pengetahuan mencuci tangan , pengetahuan penunggu pasien, RTI, RSUP Sanglah
The Effect of Giving Human Umbilical Cord Mesenchymal Stem Cells (HUMSC) on the Expression of Collagen I in Menopause Model Mice Marta, Kadek Fajar; AAN Jaya Kusuma; Ida Bagus Aditya Mayanda; IB Yudhistira Anantasurya Vidhisvara; Juventius Anggoa
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 1 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i1.905

Abstract

Background: Patients with pelvic floor dysfunction (PFD) who fail conservative treatment will undergo surgery. In recent years, various therapeutic approaches for PFD using stem cells have been investigated in vivo. One component of stem cells is the human umbilical cord mesenchymal stem cell (HUMSC). It is hoped that HUMSC can modify the collagen and elastin content in the extracellular matrix, leading to improvements in pelvic floor strength and PFD. Methods: This research is an experimental study with a randomized posttest-only controlled group design with the aim of determining the effect of giving HUMSC on the expression of Collagen I in a female mouse model of menopause. There are inclusion criteria, namely female Balb/c mice, healthy, never mated, aged 8 - 12 weeks, and body weight 18 - 22 grams. The research will be carried out with statistical analysis using SPSS; a p-value <0.05 is considered significant. Results: The results of the analysis of the distribution of sample means show that there are significant differences between the two groups. The treatment group had a higher mean expression of type I collagen compared to the control group. In addition, variation in the control group was lower compared with the treatment group, which could be interpreted as higher consistency in the response to HUMSC treatment. Conclusion: Human umbilical cord (HUMSC) has a positive impact on type I collagen expression in menopausal model mice.
The Effect of Giving Human Umbilical Cord Mesenchymal Stem Cells (HUMSC) on the Expression of Collagen I in Menopause Model Mice Marta, Kadek Fajar; AAN Jaya Kusuma; Ida Bagus Aditya Mayanda; IB Yudhistira Anantasurya Vidhisvara; Juventius Anggoa
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 1 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i1.905

Abstract

Background: Patients with pelvic floor dysfunction (PFD) who fail conservative treatment will undergo surgery. In recent years, various therapeutic approaches for PFD using stem cells have been investigated in vivo. One component of stem cells is the human umbilical cord mesenchymal stem cell (HUMSC). It is hoped that HUMSC can modify the collagen and elastin content in the extracellular matrix, leading to improvements in pelvic floor strength and PFD. Methods: This research is an experimental study with a randomized posttest-only controlled group design with the aim of determining the effect of giving HUMSC on the expression of Collagen I in a female mouse model of menopause. There are inclusion criteria, namely female Balb/c mice, healthy, never mated, aged 8 - 12 weeks, and body weight 18 - 22 grams. The research will be carried out with statistical analysis using SPSS; a p-value <0.05 is considered significant. Results: The results of the analysis of the distribution of sample means show that there are significant differences between the two groups. The treatment group had a higher mean expression of type I collagen compared to the control group. In addition, variation in the control group was lower compared with the treatment group, which could be interpreted as higher consistency in the response to HUMSC treatment. Conclusion: Human umbilical cord (HUMSC) has a positive impact on type I collagen expression in menopausal model mice.
Co-Authors AAN Jaya Kusuma I Gusti Agung Gede Utara Hartawan IB Yudhistira Anantasurya Vidhisvara Juventius Anggoa Marta, Kadek Fajar