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Yu Zen-ji
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THE ACUTE TOXICITY AND BONE-MERROW MICRONUCLEUS TESTS OF WATER EXTRACT FROM Avicennia marina FRUITS IN MICE Gao Xiu-mei; Han Wei-Dong; Yu Zen-ji
JOURNAL OF COASTAL DEVELOPMENT Vol 11, No 2 (2008): Volume 11, Number 2, Year 2008
Publisher : JOURNAL OF COASTAL DEVELOPMENT

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Abstract

The acute toxicity and mutagenesis of water extract from Avicennia marina fruits in mice were studiedwith the oral acute toxicity test according to Karber’s method and the bone-marrow micronucleus testfor mutagenic observation.The results showed the water extract from A. marina fruits presented theacuteper oral toxicity at LD50 >10.000 mg/kg; the bone-marrow nicrobucleus test indicated no mutageniceffects. Water extract from A.Marina fruits belong to non toxic compounds and has no mutagenic effectsunder the experimental conditions.
Co-Authors Gao Xiu-mei Han Wei-Dong