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I Komang Kari

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Author-ID : 295657

Health Professions Medicine & Pharmacology

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ACCURACY OF RAPID TEST OF STORED ACUTE PHASE SERUM FOR DIAGNOSE JAPANESE ENCEPHALITIS Subanada, Ida Bagus; Kari, I Komang
Medicina Vol 44 No 1 (2013): Januari 2013
Publisher : Medicina

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1228.882 KB)

Japanese encephalitis (JE) is common viral encephalitis with high sequele and mortality. With some limitations, there are several diagnostic tool to diagnose of JE. The objecive of this study was to know the accuracy of rapid test of stored acute phase serum for diagnose of JE. We conducted diagnostic test of stored acute phase serum of encephalitis patients with MAC ELISA of cerebrospinal fluid as a gold standard. Sensitivity, specificity, positive predictive value (PPV), negative predictive value NPV), positive likelihood ratio (PLR), negative likelihood ratio (NLR), and post-test probability were calculated. This study found the prevalence of JE was 42.1%, sensitivity 15.7 % (95% CI 9.2 to 22.2%), specificity 95.7% (95% CI 92.1 to 99.3%), PPV 72.7% (95% CI 64.8 to 80.6%), NPV 60.9% (95% CI 52.2 to 69.6%), PLR 3.7, NLR 0.9, and post-test probability was 0.73. We concluded that rapid test of acute phase stored serum was insensitive but specific to diagnose of JE.

Neurological impairment of children with history of prematurity and neonatal hyperbilirubinemia Ida Bagus Subanada; I Komang Kari; Abdul Hamid
Paediatrica Indonesiana Vol 43 No 2 (2003): March 2003
Publisher : Indonesian Pediatric Society

Background In premature infants, the incidence of hyperbiliru-binemia is still high. Bilirubin encephalopathy can develop withoutmarked hyperbilirubinemia.Objective To know the incidence of neurological impairment inpremature with hyperbilirubinemia and the association betweenneurological impairment and serum unconjugated billirubin con-centration.Methods A retrospective study was conducted on 54 prematureswith history of hyperbilirubinemia and 54 without history of hyper-bilirubinemia born between 1997 and 1998 and discharged fromSanglah Hospital. Consecutive sampling was done. After univariateanalysis, multivariate analysis was used to identify the associationbetween serum unconjugated bilirubin concentration and neuro-logical impairment at the adjusted age of 318 months.Results There were statistically significant differences in mean ofage and neurological impairment between subjects with and with-out hyperbilirubinemia (p<0.0001 and 0.026). In subjects with hy-perbilirubinemia, univariate analysis showed significant differencesin means of serum unconjugated bilirubin concentration, gesta-tional age, birth weight, and serum albumin concentration betweensubject who had neurological impairment and who had no neuro-logical impairment with p = 0.005; 0.001; 0.002; <0.0001, respec-tively. Multivariate analysis found there were association betweenneurological impairment and serum unconjugated bilirubin concen-tration, gestational age, and serum albumin concentration withp<0.0001; 0.004; and <0.0001, respectively.Conclusion Neurological impairment in subject with hyperbiliru-binemia was greater than subject without hyperbilirubinemia. Se-rum unconjugated bilirubin concentration is one of three factorsthat associated with neurological impairment

Neurocysticercosis M Arimbawa; I Komang Kari; N S Laksminingsih
Paediatrica Indonesiana Vol 44 No 4 (2004): July 2004
Publisher : Indonesian Pediatric Society

In this paper we report a case of NCC in an 11-year old Balinese boy.

Clinical profiles and some associated factors of Japanese encephalitis in Bali I Komang Kari; Wei Liu; I Made Kompiang Gautama; I Ketut Subrata; Zhi Yi Xu
Paediatrica Indonesiana Vol 46 No 1 (2006): January 2006
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi46.1.2006.13-9

Background Japanese Encephalitis (JE) is a mosquito-borne vi-ral disease that can affect the central nervous system and causeseveral complications and death. In Indonesia, particularly in Bali,studies of JE in humans are still very limited.Objective To assess the clinical manifestations and outcome ofJE in Bali and to identify some possible associated factors andmonthly distribution of admission to the hospitals.Methods A cross-sectional study was conducted in 8 district hospi-tals, army hospital, and Sanglah central hospital, as surveillance cen-ters in Bali, from July 2001 through January 2003. Subjects less than12 years of age and residences of Bali province who were suspectedof having acute viral encephalitis, aseptic meningitis, and acute flac-cid paralysis referred from all health facilities were included in thisstudy. The diagnosis of JE was established by detection of virus-spe-cific IgM in CSF and serum, with IgM capture enzyme-linkedimmunosorbent assay (MAC ELISA)Results During the study, 158 subjects with encephalitis were in-cluded; 55 (34.8%) were caused by JE and 103 (65.2%) were causedby non-JE. It showed that pig owning and rice farming were signifi-cantly associated with JE (PR= 3.02, 95% CI 1.29; 7.10; P= 0.009and PR= 2.86, 95% CI 1.30; 6,31, P= 0.008, respectively). Mostsubjects (46.2%) were under 2 years old with mean age of 37.24(SD 32.24) months. Forty-two (26.6%) subjects had nuchal rigidity,and all of them had aseptic meningitis. Denpasar had the highestprevalence of non-JE cases. Bangli and Klungkung had the lowestprevalence of JE and non-JE. The highest prevalence of JE was inGianyar. Peak prevalences of JE were in April and May 2002. Peakprevalences of non-JE were during August-October 2001 and inMarch-April 2002. Four (7.3%) subjects of JE group and 25 (24.3%)subjects of non-JE died. There were 25 (45.5%) out of 55 subjectswho survived with disability. Twenty-four (43.6%) JE subjects and34 (33.0%) non-JE subjects had good outcome.Conclusions Around one third of the subjects were positively di-agnosed as JE. The highest prevalence of JE was found in Gianyar.Peak prevalences of JE are in April and May 2002. Pig owning andrice farming are associated factors. Almost half of JE subjects sur-vived with disability

Intracardiac rhabdomyoma in a newborn with tuberous sclerosis I Kadek Suarca; Ida Bagus Agung Winaya; I Komang Kari
Paediatrica Indonesiana Vol 46 No 6 (2006): November 2006
Publisher : Indonesian Pediatric Society

Primary congenital cardiac tumors, especiallyintracardiac tumors, are rare in children.Rhabdomyoma is the most common oneand usually diagnosed in the first few days oflife. Referral from pediatric cardiac centers found thatthe incidence of cardiac tumors was 0.08%-0.20%.Rhabdomyoma represents 36%-42% in autopsy seriesand 79% in clinical series.

Anti-Diphtheric Toxin Antibodies in Healthy Children in Kindergartens Using the Immunoenzymatic Assay Method Santoso, Hendra; Suwendra, I Putu; Kari, I Komang
Paediatrica Indonesiana Vol. 30 No. 9-10 (1990): September-October 1990
Publisher : Indonesian Pediatric Society

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Although the immunization program for children in Indonesia follows the WHO recommendation, in some areas high diphtheric morbidity rates still occur for children under 5 years of age. This study deals with the ELISA for immunoglobulin G antibodies against diphtheric toxin in healthy children in kindergartens to determine the immunity status. One hundred and ninety eight samples of serum were collected from children of 18 kindergartens in West, East and South Denpasar districts and were investigated for Ig G diphtheria using the ELISA method. History of immunization was obtained from the patient's immunization cards and an interview by the doctors. It was assumed to be immune when the lg G level was above 0.01 IU/ml. Eighty one out of 95 (85%) children from the control group (who had never had basic immunization) had Ig G levels above 0.01 IU/ml and 81 out of 83 (97.6%) children from the group who had completed basic immunization (3 injections) had Ig G level above 0.01 IU/ml. It seemed that natural infection played still a major role to develop immunity in those children.

Co-Authors ABDUL HAMID Hendra Santoso I Kadek Suarca I Ketut Subrata I Made Kompiang Gautama Ida Bagus Agung Winaya Ida Bagus Subanada M Arimbawa Nyoman Srie Laksminingsih Suwendra, I Putu Wei Liu Zhi Yi Xu

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