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Potentials of rose (Rosa damascena) petals and receptacles extract as antioxidant and antihyaluronidase Desi Yustra Sari Dewi; Chrismis Novalinda Ginting; Linda Chiuman; Ermi Girsang; Rr. Anisa Siwianti Handayani; Wahyu Widowati
Pharmaciana Vol 10, No 3 (2020): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Free radicals affect aging by unspecific lead breakdown to macromolecules, like DNA, lipids, and proteins. The degradation of the extracellular matrix affects skin aging and correlated with the hyaluronidase enzyme. Rose (Rosa damascena) petal extract and rose receptacle extract can scavenge free radicals, thus hindering the aging process. This study examines phenolic and flavonoid content, the antioxidant, anti-hyaluronidase potential owned by rose petal extract (RPE), and rose receptacle extract (RRE) inhibiting skin aging. In this study, Hydrogen peroxide (H2O2) scavenging activity assay was done to analyze the antioxidant activity while the hyaluronidase inhibitory assay analyzed antiaging activity. The characteristic of RPE and RRE were measured the phenolics and flavonoids content. The phenolics content of Â RPE and RRE were 9.66 Î¼g GAE/mg RPE andÂ 4.31 Â Î¼g GAE/mg RRE, respectively, while the flavonoids content of Â RPE and RRE respectively 1.22 Î¼g QE/mg RPE and 0.59 Î¼g QE/mg RRE. The median inhibitory (IC50) of H2O2 scavenging of RPE (207.99 Âµg/mL) was more active than RRE (348.24 Âµg/mL). RPE's anti-hyaluronidase (IC50: 51.68 Âµg/mL) is as effective as RRE (IC50: 51.98 Âµg/mL). Antioxidant and antiaging activities possessed by RPE and RRE are promising natural agents for aging therapy.

Prevalence and Determinants of Stunting Incidence in Toddlers Tiorismasni Zai; Ermi Girsang; Sri Lestari Ramadhani Nasution; Chrismis Novalinda Ginting
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 7, No 2: June 2022
Publisher : Universitas Aisyah Pringsewu

The incidence of stunting in children under five is still the main cause of death in children under five in the world because the impact of stunting is not only on health problems but is closely related to the level of intelligence of children. This study aims to determine the prevalence and investigate the determinants of stunting in children under five. This study is quantitative research with a cross-sectional design. The population of this study was all mothers of children under five who visited the Mandrehe Barat Non-Inpatient Puskesmas in 2021, and the research sample was 200 mothers of children under five. Data was collected directly by distributing questionnaires to mothers of children under five. Then, continued with the process of data analysis with the chi-square test and binary logistic regression. The results showed that exclusive breastfeeding (p= less than 0.001; PR= 9.5; 95% CI 6.788-22.948), feeding patterns (p= less than 0.001; PR = 7.6; 95%CI 4.833-12.266), and consumption of vitamin A and zinc during pregnancy (p= less than 0.001; PR = 4.4; 95%CI 3.172-6.043) had a significant effect on the incidence of stunting, but a history of low birth weight (p= 0.785; PR= 1.08; 95% CI 0.372-3.306) and history of infectious disease (p=0.111; PR=1.5; 95%CI 0.978-2.441) were not significant for the incidence of stunting. Furthermore, the dominant factor in the incidence of stunting shows that toddlers who are stunted are 5.7 times more likely not to be given exclusive breastfeeding compared to toddlers who are not stunted. Thus, mothers of children under five are expected to take the time to visit health services by bringing their children under five to monitor their growth and development of children such as height and weight according to the child's age. Abstrak: Kejadian stunting pada anak balita hingga saat ini masih merupakan penyebab utama kematian pada anak balita di dunia, karena dampak stunting bukan hanya pada masalah kesehatan, namun, sangat erat kaitannya pada tingkat kecerdasan anak. Penelitian ini bertujuan untuk mengetahui prevalensi dan menyelidiki determinan kejadian stunting pada balita. Studi ini merupakan penelitian kuantitatif dengan desain crossectional. Populasi penelitian ini adalah seluruh ibu balita yang berkunjung di Wilayah Puskesmas Non Rawat Inap Mandrehe Barat Tahun 2021, dan sampel penelitian sebanyak 200 orang ibu balita. Pengumpulan data dilakukan secara langsung dengan menyebarkan kuesioner kepada ibu balita. Kemudian, dilanjutkan dengan proses analisis data dengan uji Chi Square dan regresi logistik biner. Hasil penelitian menunjukkan bahwa pemberian ASI Eksklusif (p=kurang dari 0,001;PR=9,5;95%CI 6,788-22,948), pola pemberian makan (p= kurang dari 0,001; PR=7,6; 95%CI 4,833-12,266), dan konsumsi vitamin A dan Zinc pada masa kehamilan (p= kurang dari 0,001;PR=4,4; 95%CI 3,172-6,043) berpengaruh signifikan terhadap kejadian stunting, namun riwayat BBLR (p=0,785; PR=1,08;95% CI 0,372-3,306) dan riwayat penyakit infeksi (p=0,111; PR=1,5; 95%CI 0,978-2,441) tidak signifikan terhadap kejadian stunting. Selanjutnya, faktor dominan terhadap kejadian stunting menunjukkan bahwa balita yang mengalami stunting 5,7 kali kecenderungannya tidak diberi ASI Eksklusif dibanding dengan balita yang tidak mengalami stunting. Dengan demikian, kepada ibu balita diharapkan agar melungkan waktu untuk berkunjung ke tempat pelayanan kesehatan dengan membawa anak balita untuk memantau tumbuh kembang anak seperti tinggi dan berat badan sesuai usia anak.

Prevalence and Determinants of Drug Adherence in Type 2 Diabetes Mellitus Patients Tuho Konsultasi Mendrofa; Ermi Girsang; Sri Lestari Ramadhani Nasution; Chrismis Novalinda Ginting
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 7, No 1: March, 2022
Publisher : Universitas Aisyah Pringsewu

Compliance with type 2 patients with DM in taking medication is an important key in maintaining blood glycemic levels and preventing complications. This study was conducted to determine the prevalence and to investigate the determinants of medication adherence in type 2 patients with DM. A total of 250 types 2 patients with DM who visited Pulau Tello Health Center, South Nias Regency, were involved in this cross-sectional study. Collecting data using questionnaires and patient medical records. The results showed that the motivational variables (p= less than 0.001; PR= 2; 95%CI 1.560-2.668), family support (p= less than 0.001; PR = 4.2; 95%CI 2.827-6.496), individual coping (p = less than 0.001; PR=1.9; 95%CI 1.409-2.267), and income (p= less than 0.001; PR=1.7; 95%CI 1.346-2.258) were associated with medication adherence in type 2 patients with DM. family is the dominant variable that influences medication adherence in type 2 patients with DM. Patients with DM who does not adhere to medication are 7.8 times more likely to have poor support than patients who adhere to medication.Abstrak: Kepatuhan pasien DM tipe 2 dalam mengonsumsi obat menjadi kunci penting dalam menjaga glikemik darah dan pencegahan komplikasi. Studi ini dilakukan untuk mengetahui prevalensi dan menyelidiki determinan kepatuhan minum obat pada pasien DM tipe 2. Sebanyak 250 orang pasien DM tipe 2 yang berkunjung di Puskesmas Pulau Tello, Kabupaten Nias Selatan dilibatkan dalam studi cross-sectional ini. Pengumpulan data menggunakan kuesioner dan rekam medis pasien. Hasil penelitian menunjukkan bahwa variable motivasi (p= kurang dari 0,001; PR= 2; 95%CI 1,560-2,668), dukungan keluarga (p= kurang dari 0,001;PR = 4,2; 95%CI 2,827-6,496), koping individu (p= kurang dari 0,001; PR=1,9; 95%CI 1,409-2,267), dan pendapatan (p= kurang dari 0,001; PR= 1,7; 95%CI 1,346-2,258) berhubungan dengan kepatuhan minum obat pasien DM tipe 2. Dukungan keluarga merupakan variabel yang dominan berpengaruh terhadap kepatuhan minum obat pada pasien DM tipe 2. Pasien DM yang tidak patuh minum obat 7,8 kali kecenderungannya memiliki dukungan yang kurang baik dibanding dengan pasien yang patuh minum obat.

Utilization of Online Learning Modules to Increase Nurse Capacity in the Implementation of Nursing Care Documentation Feri Irawan; Chrismis Novalinda Ginting; Sri Wahyuni Nasution
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 7, No 1: March, 2022
Publisher : Universitas Aisyah Pringsewu

Nursing care documentation is still a problem in many developing countries due to individual and organizational factors. Providing education is believed to be able to improve the competence and compliance of nurses in documenting nursing care. This study analyzes the use of online learning modules to increase the capacity of nurses in the implementation of nursing care documentation at Rantau Prapat city administration public hospital. The type of research used is a quasi-experimental approach with a pre-post test design approach with a control group. The population in this study were all nurses in the inpatient ward of Rantau Prapatcity administration public hospital, totalling 160 people and a sample of 31 nurses for the intervention group and 31 nurses for the control group. Collecting data with primary and secondary data and the data were analyzed using the Mann–Whitney test. The results showed that there were differences in the knowledge, attitudes and actions of nurses regarding the documentation of nursing care before and after the online module learning was performed. The increase in scores on these three aspects was higher in the intervention group than in the control group. Clinical supervision by the head of the room is also recommended to be performed regularly and continuously so that nurses can be motivated in improving documentation that is oriented toward quality nursing care services. Abstrak: Pendokumentasian asuhan keperawatan masih menjadi permasalahan di berbagai negara berkembang dikarenakan faktor individual maupun faktor organisasional. Pemberian edukasi dipercaya mampu meningkatkan kompetensi dan kepatuhan perawat dalam melakukan pendokumentasian asuhan keperawatan. Penelitian ini bertujuan untuk menganalisis penggunaan modul pembelajaran online untuk meningkatkan kapasitas perawat dalam pelaksanaan pendokumentasian asuhan keperawatan di RSUD Rantau Prapat. Jenis penelitian yang digunakan adalah quasi experiment dengan pendekatan pre-post test design with control group. Populasi dalam penelitian ini adalah seluruh perawat pelaksana di ruang rawat inap RSUD Rantau Prapat yang berjumlah 160 orang dan sampel sebanyak 31 perawat untuk kelompok intervensi dan 31 perawat untuk kelompok kontrol. Pengumpulan data dengan data primer dan sekunder dan data dianalisis dengan uji Mann-Whitney. Hasil penelitian menunjukkan bahwa terdapat perbedaan pengetahuan, sikap dan tindakan perawat tentang pendokumentasian asuhan keperawatan sebelum dan sesudah dilakukan pembelajaran modul online. Peningkatan skor pada ketiga aspek tersebut lebih tinggi pada kelompok intervensi dibandingkan pada kelompok kontrol. Supervisi klinis oleh kepala ruangan juga dianjurkan untuk dilakukan secara teratur serta berkelanjutan agar perawat dapat termotivasi dalam meningkatkan pendokumentasian yang berorientasi pada pelayanan asuhan keperawatan yang berkualitas.

Experience and Quality of Life of Health Workers Infected with COVID-19 in Gunung Sitoli John Handy Mendrofa; Ermi Girsang; Sri Lestari Ramadhani Nasution; Chrismis Novalinda Ginting
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 7, No 3: September 2022
Publisher : Universitas Aisyah Pringsewu

The task of handling and caring for people infected with COVID-19 places the position of health workers in a high-risk group. Health workers not only face physical problems when infected, the mental burden due to fears of infecting family members while doing self-isolation, and the negative stigma that develops in the community. This research is a qualitative descriptive study using a phenomenological study design. The phenomenon studied is about the experience and quality of life of health workers infected with COVID-19 in Gunungsitoli City. The study was conducted from April to May 2021. In collecting data, researchers interviewed 10 health workers consisting of 2 doctors and 8 nurses. The processed data are displayed in narrative text. The results showed that infected health workers experienced stress and physical disorders such as fever, difficulty breathing, tired easily to digestive disorders that hindered physical activity and social interaction with family members. In this study, the role of psychological support from family and co-workers is quite important in improving the health status of patients who are self-isolating. Given the negative stigma toward patients and health workers infected with COVID-19, efforts to overcome the negative stigma require collaboration from the government, mass media, and religious leaders as well as community leaders. Abstrak: Tugas penanganan dan perawatan orang yang terinfeksi COVID-19 menempatkan posisi petugas kesehatan dalam kelompok beresiko tinggi. Petugas kesehatan tidak hanya menghadapi gangguan fisik ketika terinfeksi, beban mental akibat kekhawatiran menulari anggota keluarga saat melakukan isolasi mandiri dan stigma negatif yang berkembang di masyarakat. Penelitian ini merupakan penelitian deskriptif kualitatif dengan menggunakan desain studi fenomenologi. Adapun fenomena yang diteliti adalah mengenai pengalaman dan kualitas hidup tenaga kesehatan yang terinfeksi COVID-19 di Kota Gunungsitoli. Penelitian dilaksanakan pada bulan April hingga Mei 2021. Dalam pengumpulan data, peneliti mewawancarai sebanyak 10 orang tenaga kesehatan yang terdiri dari 2 dokter dan 8 perawat. Data yang telah diolah ditampilkan dalam teks naratif. Hasil penelitian menunjukkan tenaga kesehatan yang terinfeksi mengalami stress dan gangguan fisik seperti demam, susah nafas, mudah lelah hingga gangguan pencernaan menghambat aktivitas fisik dan interaksi sosial dengan anggota keluarga. Dalam studi ini, peran dukungan psikis dari keluarga dan rekan kerja cukup penting dalam perbaikan status kesehatan pasien yang isolasi mandiri. Mengingat stigma negatif terhadap pasien dan tenaga kesehatan yang terinfeksi COVID-19, upaya untuk mengatasi hal tersebut memerlukan kolaborasi pemerintah, media massa dan tokoh agama serta tokoh masyarakat.

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