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All Journal Pharmaciana: Jurnal Kefarmasian Prosiding Seminar Biologi INDRA: Jurnal Pengabdian kepada Masyarakat
Andi Dian Permana
Department of Pharmaceutics, Faculty of Pharmacy, Hasanuddin University,
Agriculture, Biological Sciences & Forestry Health Professions Medicine & Pharmacology

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Formulasi Ekstrak Buah Mengkudu (Morinda citrifolia) dalam Bentuk Sediaan Transdermal Liposome Cream Amrianto Amrianto; Mukarramah Mukarramah; Dike Dandari Sukmana; Nurun Nahda; Andi Dian Permana
Prosiding Seminar Biologi Vol 3 No 1 (2017): Prosiding Seminar Nasional Biology for Life
Publisher : Jurusan Biologi, Fakultas Sains dan Teknologi, Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/psb.v3i1.4679

Abstract

Indonesia is a country rich in herbs. One of them is Noni (Morinda citrifolia). Noni fruit has good benefits for the body such as natural antioxidants and several other benefits. The use of noni fruit as herbal medicine is often used but the way make was still very inadequate to get the optimum effect on the plant. One effort that can be done is to make it a cream preparation liposomes that are used topically. Aims of this research was formulation of Transdermal liposome cream from noni fruit extract. The result showed that the total phenolic content of the extract of noni fruit was as much as 180 µg GAE/g ekstrak. The result of the evaluation of transdermal liposome cream preparation obtained both formulas have viscosity of 9,000 cps and 38.000 cps respectively, have uniform vesicle shape, high adsorption efficiency of 95% and 96,67%, but in formula 2 pH obtained did not fulfill the criteria of topical preparation, while formula 1 fulfilled the criterion that is 6,5. From these results it can be concluded that the noni fruit extract can be prepared in the form of transdermal cream preparations which have good physical characteristics achieved by formula 1.
Enhanced skin localization of doxycycline using microparticles and hydrogel: effect of oleic acid as penetration enhancer Aliyah Aliyah; Windy Winalda Oktaviana; Kadek Saka Dwipayanti; Arini Putri Erdiana; Rifka Nurul Utami; Andi Dian Permana
Pharmaciana Vol 11, No 2 (2021): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (201.674 KB) | DOI: 10.12928/pharmaciana.v11i2.21044

Abstract

One of the disadvantages of gel preparations is the poor ability to penetrate the skin. Herein we developed a sodium carboxymethylcellulose (NaCMC)-based gel containing microparticle of doxycycline hyclate (DOX).  Oleic acid (OA) was added into the gel formulation specifically to increase the penetrability of DOX microparticles. The objective of this work was to determine the effect of varying concentration of OA on the physical characteristics, penetration and retention abilities of DOX. DOX microparticles were initially prepared using PLGA as a matrix and then incorporated into a NaCMC-based gel with various OA concentrations: 0%, 2.5%, 5%, 7.5%, and 10% for F1, F2, F3, F4, and F5, respectively. The gel preparations were evaluated for their organoleptic test, homogeneity, pH measurement, viscosity, spreadability, as well as ex vivo penetration and retention abilities. The physical characteristics tests revealed a homogeneous yellow gel with a distinctive odor and pH values compatible with the pH requirements of human skin. The retention test showed the formulation retained 1236.46 µg of DOX in the skin. Finally, the skin retention of DOX from microparticles loaded gel was significantly higher compared to the free DOX loaded gel, indicating the microparticles can be extremely effective in retaining the DOX in the infected area.
Inisiasi dan pengembangan produk handsanitizer pada center of excellence Fakultas Farmasi Universitas Hasanuddin sebagai upaya pengembangan usaha intelektual kampus Muhammad Raihan; Sandra Aulia Mardikasari; Subehan Lallo; Aliyah Putranto; Nana Juniarti Natsir Djide; Muhammad Akbar Bahar; Ismail Ismail; Andi Dian Permana; Yayu Mulsiani Evary; Abdul Rahim
INDRA: Jurnal Pengabdian kepada Masyarakat Vol. 4 No. 1 (2023): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/indra.v4i1.188

Abstract

PPUPIK is a community service program for 3 years. The purpose of this activity is to produce the intellectual products from the Faculty of Pharmacy UNHAS, especially Hand sanitizer and Disinfectant products, so that the Center of Excellence of the Faculty of Pharmacy UNHAS (CoE-FFUH) would become an independent business unit that able to support UNHAS' role as PTNBH. The specific target for this first year is the initiation of the development of a production unit of hand sanitizer and disinfectant products at CoE-FFUH. The initiation consists of the determination of documents for the production process, determination of product packaging material and designs, and also pilot-scale production for limited sales. As for the following year, hopefully, this product will be able to obtain a distribution permit for household health supplies (PKRT) so that the commercialization of licensed products can be carried out legally and able to produce more types of PKRT products.
Co-Authors Abdul Rahim Aliyah Aliyah Aliyah Putranto Amrianto Amrianto Dike Dandari Sukmana Ismail Ismail Kadek Saka Dwipayanti Muhammad Akbar Bahar Muhammad Raihan Mukarramah Mukarramah Nana Juniarti Natsir Djide Nurun Nahda Rifka Nurul Utami Sandra Aulia Mardikasari Solly Aryza Subehan Lallo Windy Winalda Oktaviana Yayu Mulsiani Evary