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Elisabeth Krismayanti
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jalan Raya Bandung-Sumedang Km 21, Jatinangor 45363, Sumedang

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Anti-bacterial Activity of Prenylated Xanthone from The Bark of Garcinia lowa Darwati Darwati; Elisabeth Krismayanti; Supriyatna Supriyatna; Unang Supratman
Jurnal Kimia Valensi Jurnal Kimia VALENSI Volume 2, No. 2, November 2016
Publisher : Syarif Hidayatullah State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (362.6 KB) | DOI: 10.15408/jkv.v2i2.4057

Abstract

Bioactivity-guided fractionation of a ethyl acetate extract of Garcinia lowa bark has led to the isolation and identification of a known prenylated xanthone, mangosharin, (2,6-dihydroxy-8-methoxy-5-(3-methylbut-2-enyl)-xanthone (1, 15.4 mg) The structure of the compound was identified from analysis of their spectroscopic data and by comparison with previous studies.Compound 1 showed anti-bacterial activity against Sreptococcus mutans with MIC value of 7.25 mg/mL. DOI : http://dx.doi.org/10.15408/jkv.v0i0.4057