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All Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Indonesian Journal of Rheumatology
Yuniza Yuniza
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Neuroscience Public Health

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PELUANG TERJADINYA IMMUNIZATION STRESS-RELATED RESPONSE (ISRR) SELAMA PROGRAM VAKSINASI COVID-19 Hafizzanovian Hafizzanovian; Desi Oktariana; Muhammad Ali Apriansyah; Yuniza Yuniza
JURNAL KEDOKTERAN DAN KESEHATAN Vol 8, No 3 (2021)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/JKK.V8I3.13807

Abstract

Coronavirus Disease 2019 (COVID-19) telah menjadi bencana katasropik dalam berbagai bidang, terutama bidang kesehatan. Mengingat mortalitas yang tinggi dan penyebaran yang cepat dari penyakit ini, vaksin menjadi salah satu harapan terbesar untuk dapat mengendalikan pandemi ini. Immunization stress-related response (ISRR) merupakan salah satu Kejadian Ikutan Pasca imunisasi (KIPI) yang bermanifestasi sebagai respons stres akut, reaksi vasovagal, atau reaksi gejala neurologis disosiatif (dissociative neurological symptom reactions atau DNSR) yang dapat muncul tepat sebelum, selama, atau segera setelah imunisasi. Fenomena kluster ISSR seringkali disebut juga dengan penyakit psikogenik massal. Adanya stigma negatif terhadap efektifitas dan keamanan vaksin Covid-19 dapat membuka peluang terjadinya kluster ISRR yang dapat membuat masyarakat semakin sungkan untuk menerima imunisasi sehingga menyebabkan gagalnya program imunisasi. Langkah preventif dapat meminimalkan risiko ISRR, dan jika ISRR terjadi, maka identifikasi yang cepat, diagnosis, dan manajemen yang tepat dapat mengurangi dampaknya.
Effect of Vitamin D Supplementation on Regulatory T Cells of Systemic LupusErythematosus: A Systematic Review Yuniza Yuniza
Indonesian Journal of Rheumatology Vol. 15 No. 2 (2023): IJR VOL 15 No 2
Publisher : Indonesian Rheumatology Associantion

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/IJR.v15i2.251

Abstract

Background. Systemic lupus erythematosus (SLE) is associated with aglobal reduction in regulatory T cells (Tregs). Vitamin D supplementationthat is efficacious, safe, and reasonably priced has the potential to reducemorbidity in SLE. This study was aimed to systematically assess the efficacyof vitamin D supplementation in enhancing Tregs concentration or Tregsrelated marker. Methods. A systematic review of the literature for clinicalstudies was performed on Pubmed, Proquest, and Google Scholar. Studieswere assessed for risk of bias using Newcastle Ottawa Scale. All clinicalstudies that investigated the effects of vitamin D supplementation on Tregsin SLE patients were included. Key evidence was analyzed and qualitativelysynthesized. Results. Three relevant studies were included. All studies wereof high-quality. Vitamin D supplementation consistently increased Tregsconcentration across all included studies. Conclusion. The current studysupports the evidence that vitamin D supplementation enhanced Tregsconcentration in SLE patients. 
Co-Authors Hafizzanovian Hafizzanovian Muhammad Ali Apriansyah Oktariana, Desi